Abstract
Computational fluid dynamics (CFD) studies on cerebral aneurysms have attempted to identify surrogate hemodynamic parameters to predict rupture risk. We present a case of bilateral mirror image aneurysms, one of which ruptured soon after imaging. Wall shear stress values of the ruptured aneurysm changed by 20–30 % after rupture because of change in the aneurysm shape. Findings from our case suggest that CFD studies comparing unruptured and ruptured aneurysms may not yield valid estimation on aneurysm rupture risk because of changes in aneurysm shape after rupture. Changes in aneurysm shape after rupture should be considered in CFD research.
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References
Castro MA, Putman CM, Sheridan MJ, Cebral JR (2009) Hemodynamic patterns of anterior communicating artery aneurysms: a possible association with rupture. AJNR Am J Neuroradiol 30:297–302
Cebral JR, Castro MA, Putman CM, Alperin N (2008) Flow-area relationship in internal carotid and vertebral arteries. Physiol Meas 29:585–594
Cebral JR, Mut F, Weir J, Putman C (2011) Quantitative characterization of the hemodynamic environment in ruptured and unruptured brain aneurysms. AJNR Am J Neuroradiol 32:145–151
Cebral JR, Putman CM, Alley MT, Hope T, Bammer R, Calamante F (2009) Hemodynamics in normal cerebral arteries: qualitative comparison of 4D phase-contrast magnetic resonance and image-based computational fluid dynamics. J Eng Math 64:367–378
Gwilliam MN, Hoggard N, Capener D, Singh P, Marzo A, Verma PK, Wilkinson ID (2009) MR derived volumetric flow rate waveforms at locations within the common carotid, internal carotid, and basilar arteries. J Cereb Blood Flow Metab 29:1975–1982
Ishikawa T, Nakayama N, Yoshimoto T, Aoki T, Terasaka S, Nomura M, Takahashi A, Kuroda S, Iwasaki Y (2006) How does spontaneous hemostasis occur in ruptured cerebral aneurysms? Preliminary investigation on 247 clipping surgeries. Surg Neurol 66:269–275
Jou LD, Lee DH, Morsi H, Mawad ME (2008) Wall shear stress on ruptured and unruptured intracranial aneurysms at the internal carotid artery. AJNR Am J Neuroradiol 29:1761–1767
Kawaguchi T, Nishimura S, Kanamori M, Takazawa H, Omodaka S, Sato K, Maeda N, Yokoyama Y, Midorikawa H, Sasaki T, Nishijima M (2012) Distinctive flow pattern of wall shear stress and oscillatory shear index: similarity and dissimilarity in ruptured and unruptured cerebral aneurysm blebs. J Neurosurg 117:774–780
Kono K, Fujimoto T, Shintani A, Terada T (2012) Hemodynamic characteristics at the rupture site of cerebral aneurysms: a case study. Neurosurgery 71:E1202–E1209
Kono K, Shintani A, Fujimoto T, Terada T (2012) Stent-assisted coil embolization and computational fluid dynamics simulations of bilateral vertebral artery dissecting aneurysms presenting with subarachnoid hemorrhage: case report. Neurosurgery 71:E1192–E1201
Kono K, Terada T (2013) Hemodynamics of eight different configurations of stenting for bifurcation aneurysms. AJNR Am J Neuroradiol. doi:10.3174/ajnr.A3479
Malek AM, Alper SL, Izumo S (1999) Hemodynamic shear stress and its role in atherosclerosis. JAMA 282:2035–2042
Omodaka S, Sugiyama S, Inoue T, Funamoto K, Fujimura M, Shimizu H, Hayase T, Takahashi A, Tominaga T (2012) Local hemodynamics at the rupture point of cerebral aneurysms determined by computational fluid dynamics analysis. Cerebrovasc Dis 34:121–129
Rahman M, Ogilvy CS, Zipfel GJ, Derdeyn CP, Siddiqui AH, Bulsara KR, Kim LJ, Riina HA, Mocco J, Hoh BL (2011) Unruptured cerebral aneurysms do not shrink when they rupture: multicenter collaborative aneurysm study group. Neurosurgery 68:155–160
Shojima M, Oshima M, Takagi K, Torii R, Hayakawa M, Katada K, Morita A, Kirino T (2004) Magnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysms. Stroke 35:2500–2505
Steinman DA, Hoi Y, Fahy P, Morris L, Walsh MT, Aristokleous N, Anayiotos AS, Papaharilaou Y, Arzani A, Shadden SC, Berg P, Janiga G, Bols J, Segers P, Bressloff NW, Cibis M, Gijsen FH, Cito S, Pallarés J, Browne LD, Costelloe JA, Lynch AG, Degroote J, Vierendeels J, Fu W, Qiao A, Hodis S, Kallmes DF, Kalsi H, Long Q, Kheyfets VO, Finol EA, Kono K, Malek AM, Lauric A, Menon PG, Pekkan K, Esmaily Moghadam M, Marsden AL, Oshima M, Katagiri K, Peiffer V, Mohamied Y, Sherwin SJ, Schaller J, Goubergrits L, Usera G, Mendina M, Valen-Sendstad K, Habets DF, Xiang J, Meng H, Yu Y, Karniadakis GE, Shaffer N, Loth F (2013) Variability of computational fluid dynamics solutions for pressure and flow in a giant aneurysm: the ASME 2012 Summer Bioengineering Conference CFD Challenge. J Biomech Eng 135:021016
Takao H, Murayama Y, Otsuka S, Qian Y, Mohamed A, Masuda S, Yamamoto M, Abe T (2012) Hemodynamic differences between unruptured and ruptured intracranial aneurysms during observation. Stroke 43:1436–1439
Xiang J, Natarajan SK, Tremmel M, Ma D, Mocco J, Hopkins LN, Siddiqui AH, Levy EI, Meng H (2011) Hemodynamic-morphologic discriminants for intracranial aneurysm rupture. Stroke 42:144–152
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Kono, K., Tomura, N., Yoshimura, R. et al. Changes in wall shear stress magnitude after aneurysm rupture. Acta Neurochir 155, 1559–1563 (2013). https://doi.org/10.1007/s00701-013-1773-2
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DOI: https://doi.org/10.1007/s00701-013-1773-2