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Frontal transcortical approach in 12 Central Neurocytomas

  • Clinical Article
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Abstract

Background

Central neurocytomas (CN) are rare intraventricular tumors with benign clinical behavior that typically affect young adults. Although a favorable prognosis is generally expected after adequate management, there is no general consensus on the standard of therapy. We evaluated the efficacy and safety of radical surgery for the management of CN.

Methods

Between 1996 and 2010, 12 patients with CN (eight males and four females; range, 18 to 62 years; mean age, 28.5 years) were surgically treated in our institution. The initial goal of therapy was complete resection through a frontal transcortical approach, and repeat surgery was done in cases of residual or recurrent disease. The mean follow-up period was 51.2 months (range, 14–149 months).

Results

Complete resection was achieved in all patients either with primary (nine patients, 75 %) or second-look surgery (three patients, 25 %). No mortalities occurred and there were four surgery-related complications (two events of transient hemiparesis, one transient aphasia, and onepostoperative subdural hygroma). All patients were alive with normal activities of daily living at the last follow-up. Two patients (16.6 %) experienced a single recurrence at 26 and 66 months, one of whom underwent redo-surgery.

Conclusion

For the management of CN, complete resection is feasible, effective, and safe. Repeat surgery may be a viable option in cases of residual or recurrent disease and the use of radiotherapy can be avoided in this young population.

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Conflicts of interest

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Authors and Affiliations

  1. Department of Neurosurgery, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea

    Eun Suk Park

  2. Department of Neurological Surgery, University of Ulsan College of Medicine, Asan Medical Center, Pungnap-2 dong, Songpa-gu, Seoul, 138-736, Korea

    Young Hyun Cho, Jeong Hoon Kim & Chang Jin Kim

  3. Department of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea

    Sang Joon Kim

  4. Department of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea

    Shin Kwang Khang

Authors
  1. Eun Suk Park
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  2. Young Hyun Cho
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  3. Jeong Hoon Kim
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  4. Sang Joon Kim
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  6. Chang Jin Kim
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Corresponding author

Correspondence to Chang Jin Kim.

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Comment

There is a large body of literature on central neurocytomas and, when reviewing a new article, the first check a reviewer makes is the number of reported cases. In this respect this is certainly not a large series. The cases are, however, homogenous and well illustrated, and the Discussion on the surgical route adopted very reasonable. I think that this paper is attractive because of the simplicity and soundness of its conclusions, i.e., that whenever it is possible a complete resection, eventually after redo surgery, is the best option for these patients.

Domenico d’Avella

Padova, Italy

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Park, E.S., Cho, Y.H., Kim, J.H. et al. Frontal transcortical approach in 12 Central Neurocytomas. Acta Neurochir 154, 1961–1971 (2012). https://doi.org/10.1007/s00701-012-1490-2

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  • DOI: https://doi.org/10.1007/s00701-012-1490-2

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