Avoid common mistakes on your manuscript.
Thank you for your interesting comments outlining the sufficiency of collagen-fleece sealing for ventricular defects after carmustine wafer implantation. The use of fibrinogen-coated collagen fleeces for sealing and reconstructive procedures of ventricular defects in neurosurgery has not yet been analysed by randomised clinical trials, but their use for neurosurgical indication as a local hemostatic agent with potent prevention of cerebrospinal fluid fistula has been reported in the literature, e.g. Nistor et al. (Skull Base Surg 7:23-30, 1997). We used the fleece for several complex hemostatic and dural-reconstructive indications, including cerebral as well as spinal operative procedures. The sponge-like consistency allows comfortable and accurate modelling, with a fast adhesive effect after direct fluid contact. We share the opinion of the authors that well-designed studies are needed to analyse the potential benefit of using this agent for different neurosurgical indications compared with other biomaterials for reconstructive and watertight sealing strategies.
Conflicts of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Bock, H.C. Comment on the Letter to the editor: Bock et al. Occlusion of surgical opening of the ventricular system with fibrinogen-coated collagen fleece: a case collection study. Acta Neurochir (2011) 153:533–539. Acta Neurochir 154, 377 (2012). https://doi.org/10.1007/s00701-011-1238-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00701-011-1238-4