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Deep brain stimulation therapy for treatment-refractory Tourette’s syndrome

A review

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Abstract

Tourette’s syndrome is a chronic neurobehavioral disorder that can demonstrate refractoriness to conservative treatments, or to invasive nonsurgical treatments such as botulinum toxin infiltration, or to psychobehavioral treatments. In these cases, the surgical option is often proposed, either with lesional interventions, or more recently with deep brain stimulation (DBS). This latter modality is currently preferred because of its reversibility and modularity. Some relevant issues, however, still persist in terms of appropriate indication to treatment, selection of target, and follow-up evaluation.

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Acknowledgements

We acknowledge Ms. Olga Lee Rachello for her help in language revision, which greatly improved this manuscript.

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  1. Functional Neurosurgery Unit, IRCCS Galeazzi, Via Galeazzi 4, 20161, Milan, Italy

    Marco Sassi & Domenico Servello

  2. Movement Disorders and Tourette Center, IRCCS Galeazzi, Milan, Italy

    Mauro Porta

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  1. Marco Sassi
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Sassi, M., Porta, M. & Servello, D. Deep brain stimulation therapy for treatment-refractory Tourette’s syndrome. Acta Neurochir 153, 639–645 (2011). https://doi.org/10.1007/s00701-010-0803-6

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