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Comparison of electrode location between immediate postoperative day and 6 months after bilateral subthalamic nucleus deep brain stimulation

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Abstract

Objective

We compared the electrode positions of subthalamic nucleus (STN) deep brain stimulation (DBS) estimated at the immediate postoperative period with those estimated 6 months after surgery.

Methods

Brain CT scans were taken immediately and 6 months after bilateral STN DBS in 53 patients with Parkinson’s disease. The two images were fused using the mutual information technique. The discrepancies of electrode positions in three coordinates were measured in the fused images, and the relationship with the pneumocephalus was evaluated.

Results

The average discrepancy of x- and y-coordinates of electrode positions at the level of STN (3.5 mm below the anterior commissure–posterior commissure line) were 0.6 ± 0.5 mm (range, 0~2.1 mm) and 1.0 ± 0.8 mm (range, 0~5.2 mm), respectively. The average discrepancy of z-coordinates of the electrode tips of the fused images was 1.0 ± 0.8 mm (range, 0.1~4.0 mm). The volume of pneumocephalus (range, 0~76 ml) was correlated with the y-coordinate discrepancies (p < 0.005).

Conclusion

The electrode positions in the immediate postoperative CT might have significant discrepancies with those in the CT taken at a stable period after STN DBS especially when there is a large amount of pneumocephalus.

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Acknowledgement

This work was supported by a grant from Korea Healthcare Technology R&D project, Ministry for Health, Welfare and Family Affairs, Republic of Korea (A08-0663-A21724-08N1-000020B and A092052).

Conflicts of interest

None.

Author information

Authors and Affiliations

  1. Department of Neurosurgery, Seoul National University College of Medicine, 28 Yeongeon-dong Jongno-gu, Seoul, 110-744, South Korea

    Yong Hwy Kim, Dong Gyu Kim & Sun Ha Paek

  2. Department of Neurology, Seoul National University College of Medicine, 28 Yeongeon-dong Jongno-gu, Seoul, 110-744, South Korea

    Hee Jin Kim & Beom Seok Jeon

  3. Hypoxic/Ischemia Disease Institute, Seoul National University College of Medicine, Seoul, Republic of Korea

    Sun Ha Paek

  4. Cancer Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea

    Sun Ha Paek

  5. Clinical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea

    Dong Gyu Kim, Beom Seok Jeon & Sun Ha Paek

  6. Medical Imaging Laboratory, CyberMed, Inc., Seoul, Republic of Korea

    Cheolyoung Kim

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  1. Yong Hwy Kim
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Correspondence to Beom Seok Jeon or Sun Ha Paek.

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Kim, Y.H., Kim, H.J., Kim, C. et al. Comparison of electrode location between immediate postoperative day and 6 months after bilateral subthalamic nucleus deep brain stimulation. Acta Neurochir 152, 2037–2045 (2010). https://doi.org/10.1007/s00701-010-0771-x

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  • DOI: https://doi.org/10.1007/s00701-010-0771-x

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