Meningioma-like lesions in Erdheim Chester disease
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We are reporting a woman with bilateral, multiple, extra-axial-enhancing lesions mimicking meningiomas. Histopathology of lesions revealed the diagnosis of Erdheim Chester disease (ECD). This report provides clinical and neuroimaging findings of this disease and clues for presurgical diagnosis of ECD.
A 55-year-old female patient, a hypertensive, was admitted with generalized tonic clonic seizures, fever, cough, and drowsiness. Her symptoms had started 1 month back. Detailed work-up was done, and she was diagnosed to have diabetes insipidus. Her laboratory investigations showed hypernatremia with serum sodium level of 170, WBC count was 21.2, ESR was 94, and C-reactive protein was 20.5. Her chest X-ray showed osteopenia of visualized bone with patchy bony density at lateral ends of both clavicles. Radionuclide skeletal scintigraphy revealed diffusely increased tracer uptake over appendicular skeleton and left hemipelvis, with evidence of bony expansion and photon...
KeywordsMeningioma Diabetes Insipidus Esomeprazole Desmopressin Histiocytosis
Authors are grateful to Prof. Ather Enam FRCS, MD, PhD, Head of Neurosurgery at Aga Khan University for his contribution.