Skip to main content

Advertisement

SpringerLink
Log in

Cavernous angiomas of the lateral ventricles

  • Short Illustrated Review
  • Published:
Acta Neurochirurgica Aims and scope Submit manuscript

Abstract

Background

Cavernous angiomas are vascular malformations which rarely involve the cavities of the lateral ventricles. Knowledge of the specific clinical and neuroradiological features displayed by these lesions is limited by the scarcity of patients included in the reported series.

Objective and methods

The aim of this study was to compile and analyse the epidemiological, clinical, neuroradiological and surgical characteristics of these lesions as provided by the well-described examples reported in the scientific literature. A total of 49 were gathered, including three patients operated on recently in our Department.

Findings and conclusions

Cavernomas developing within the ventricular cavities attain a larger size than parenchymal counterpart lesions, causing symptoms and signs derived mainly from the mass effect. The characteristic parenchymal hypointense rim is less frequently identified on T2-weighted echo-gradient MRI sequences. Total surgical excision is the treatment of choice for these lesions, yet the surgical routes employed may still be associated with a high rate of neurological complications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Alves de Sousa A (2007) Cavernomes profonds (corps calleux, intraventriculaires, ganglions de la base, insulaires) et du tronc cérébral. Expérience d´une série brésilienne. Neurochirurgie 53:182–191

    PubMed  CAS  Google Scholar 

  2. Arnstein LH, Boldrey E, Naffziger HC (1951) A case report and survey of brain tumours during the neonatal period. J Neurosurg 8:315–319

    PubMed  CAS  Google Scholar 

  3. Attar A, Ugur HC, Savas A, Yüceer N, Egemen N (2001) Surgical treatment of intracranial cavernous angiomas. J Clin Neurosci 8(3):235–239

    Article  PubMed  CAS  Google Scholar 

  4. Chadduck WM, Binet EF, Farrell FW Jr, Araoz CA, Reding DL (1985) Intraventricular cavernous haemangioma: report of three cases and review of the literature. Neurosurgery 16:189–197

    PubMed  CAS  Google Scholar 

  5. Coin CG, Coin JW, Glover MB (1977) Vascular tumours of the choroid plexus: diagnosis by computed tomography. J Comput Assist Tomogr 1:146–148

    PubMed  CAS  Google Scholar 

  6. D’Angelo VA, Galarza M, Catapano D, Monte V, Bisceglia M, Carosi I (2005) Lateral ventricle tumours: surgical strategies according to tumour origin and development—a series of 72 patients. Neurosurgery 56(ONS Suppl 1):36–45

    Article  PubMed  Google Scholar 

  7. Fagundes-Pereyra WJ, Pinheiro Marques JA, de Sousa L, Cardoso de Carvalho GT, Alves de Sousa A (2000) Cavernoma do ventriculo lateral. Relato de caso. ArqNeuropsiquiatr 58(3–B):958–964

    CAS  Google Scholar 

  8. Finkelnburg R (1905) Differentialdiagnose zwischen Kleinhirntumoren und chronischem Hydrocephalus: Zugleich ein Beitrag zur Kenntnis der Angiome des Zentralnervensystems. Dtsch Z Nervenheilkd 29:135–151

    Article  Google Scholar 

  9. González Darder JM, Pesudo Martínez JV, Merino Peña J (2007) Angioma cavernoso del trígono ventricular. Caso clínico. Neurocirugía (Astur) 18:330–332

    Google Scholar 

  10. Houtteville JP (1997) Brain cavernoma: a dynamic lesion. Surg Neurol 46:610–614

    Article  Google Scholar 

  11. Houtteville JP (2007) Cavernomas of the central nervous system. Historical data and changing ideas. Neurochirurgie 53(2−3 Pt 2):117–121

    Article  PubMed  Google Scholar 

  12. Iwasa H, Indei I, Sato F (1983) Intra-ventricular cavernous haemangioma: case report. J Neurosurg 59:153–157

    PubMed  CAS  Google Scholar 

  13. Jain KK (1966) Intra-ventricular cavernous haemangioma of the lateral ventricle. J Neurosurg 24:762–764

    PubMed  CAS  Google Scholar 

  14. Jelinek J, Smirniotopoulos JG, Parisi JE, Kanzer M (1990) Lateral ventricular neoplasms of the brain: differential diagnosis based on clinical, CT, and MR findings. AJNR 11:567–574

    PubMed  CAS  Google Scholar 

  15. Kaim A, Kirsch E, Tolnay M, Steinbrich W, Radü EW (1997) Foramen of Monro mass: MRI appearances permit diagnosis of cavernous haemangioma. Neuroradiology 39:265–269

    Article  PubMed  CAS  Google Scholar 

  16. Koeller KK, Sandberg GD (2002) Cerebral intraventricular neoplasms: radiologic–pathologic correlation. RadioGraphics 22:1473–1505

    Article  PubMed  Google Scholar 

  17. Kondziolka D, Lunsford LD, Kestle JRW (1995) The natural history of cerebral cavernous malformations. J Neurosurg 83:820–824

    PubMed  CAS  Google Scholar 

  18. Kumar GSS, Poonnoose SI, Chacko AG, Rajshekhar V (2006) Trigonal cavernous angiomas: report of three cases and review of literature. Surg Neurol 65:367–371

    Article  PubMed  Google Scholar 

  19. Lynch JC, Andrade R, Pereira C, Salomao JF, Duarte F, Carvalho FG, Chadrycki E (1994) Angioma cavernoso intracraniano. Arq Neuropsiquiatr 52:224–237

    Google Scholar 

  20. McConnell TH, Leonard JS (1967) Microangiomatous malformations with intra-ventricular haemorrhage. Neurology 17:618–620

    PubMed  CAS  Google Scholar 

  21. McGuire TH, Greenwood J, Newton B (1954) Bilateral angioma of choroid plexus. J Neurosurg 11:428–430

    PubMed  CAS  Google Scholar 

  22. Merrit HH (1940) Case records of the Massachusetts General Hospital. N Engl J Med 222:191–195

    Article  Google Scholar 

  23. Michaelson PG, Warren WL, DeLone DR, Quigley MR (2004) Intra-ventricular cavernous angioma. Appl Radiol 33(12):38–40

    Google Scholar 

  24. Miyagi Y, Mannoji H, Akaboshi K, Morioka T, Fukui M (1993) Intra-ventricular cavernous malformation associated with medullary venous malformation. Neurosurgery 32:461–464

    PubMed  CAS  Google Scholar 

  25. Namba S, Ishimitsu H, Nakasone S (1979) Cavernous haemangioma of the brain. No Shinkei Geka 7:277–283

    PubMed  CAS  Google Scholar 

  26. Nieto J, Hinojosa J, Muñoz MJ, Esparza J, Ricoy J (2003) Intra-ventricular cavernomas in paediatric age. Childs Nerv Syst 19:60–62

    PubMed  CAS  Google Scholar 

  27. Notelet L, Houtteville JP, Khouri S, Lechevalier B, Chapon F (1997) Proliferative Cell Nuclear Antigen (PCNA) in cerebral cavernomas: an immuno-cytochemical study of 42 cases. Surg Neurol 7:364–370

    Article  Google Scholar 

  28. Numaguchi Y, Fukui M, Miyake E, Kishikawa T, Ikeda J, Matsura K, Tomonaga M, Kitamura K (1977) Angiographic manifestations of intracerebral cavernous haemangioma. Neuroradiology 14:113–116

    Article  PubMed  CAS  Google Scholar 

  29. Pau A, Orunesu G (1979) Vascular malformation of the brain in achondroplasia. Acta Neurochir (Wien) 50:289–292

    Article  CAS  Google Scholar 

  30. Reyns N, Assaker R, Louis E, Lejeune JP (2000) Intra-ventricular cavernomas: three cases and review of the literature. Neurosurgery 44(3):648–654

    Article  Google Scholar 

  31. Rothon ALJ (2002) The lateral and third ventricles. Neurosurgery 51(Suppl 1):207–271

    Google Scholar 

  32. Sabatier J, Gigaud M, Dubois G, Tremoulet M (1989) Cavernoma in the child. Apropos of a neonatal form with recurrence in the childhood. Neurochirurgie 35:109–110

    PubMed  CAS  Google Scholar 

  33. Schneider RC, Liss L (1958) Cavernous haemangioma of the cerebral hemispheres. J Neurosurg 15:392–399

    PubMed  CAS  Google Scholar 

  34. Sedan R, Peragut JC, Fabrici A (1989) Cavernomas and stereotactic surgery. Neurochirurgie 35:126–127

    PubMed  CAS  Google Scholar 

  35. Simard JM, García-Bengochea F, Ballinger WE, Mickle JP, Quisling RG (1986) Cavernous angioma: a review of 126 collected and 12 new clinical cases. Neurosurgery 18:162–172

    Article  PubMed  CAS  Google Scholar 

  36. Suzuki J (1988) Bifrontal anterior interhemispheric approach. In: Apuzzo MLJ (ed) Surgery of the third ventricle. Williams & Wilkins, Baltimore, pp. 489–515

  37. Tatagiba M, Schönmayr R, Samii M (1991) Intra-ventricular cavernous angioma: a survey. Acta Neurochir (Wien) 110:140–145

    Article  CAS  Google Scholar 

  38. Tatsui CE, Koerbel A, Prevedello DM, Hanel RA, Grande CV, Moro MS, Araújo JC (2003) Ressonancia magnética dos cavernomas intra-ventriculares. Arq Neuropsiquiatr 61(1):79–82

    PubMed  Google Scholar 

  39. Towfighi J, Bilaniuk T, Zimmerman RA, Langfitt TW, Gonatas NK (1976) Haemorrhages in bilateral choroid plexus haemangiomas demonstrated by computed tomography. J Neurosurg 45:218–222

    PubMed  CAS  Google Scholar 

  40. Voigt K, Yasargil MG (1976) Cerebral cavernous haemangiomas or cavernomas. Neurochirurgia (Stuttg) 19:59–68

    CAS  Google Scholar 

  41. Yamasaki T, Handa H, Yamashita J, Paine JT, Tashiro Y, Uno A, Ishikawa M, Asato R (1986) Intracranial and orbital cavernous angiomas: a review of 30 cases. J Neurosurg 64:197–208

    Article  PubMed  CAS  Google Scholar 

  42. Yasargil MG, Teddy PJ, Roth P (1985) Selective amygdalohippocampectomy. Operative anatomy and surgical technique. In: Symon L, Brihaye J, Guidetti B (eds) Advances and technical standards in neurosurgery, vol. 12. SpringerVerlag, Wien, pp 93–123

    Google Scholar 

Download references

Acknowledgements

We wish to acknowledge Prof. Sara Cowburn for her careful revision of the English language and style of the manuscript.

Author information

Authors and Affiliations

  1. Department of Neurosurgery, La Princesa University Hospital, C/ Diego de León 62, 28006, Madrid, Spain

    Rodrigo Carrasco, Manuel Pedrosa, José M. Pascual, Marta Navas, Ricardo Liberal & Rafael G. Sola

Authors
  1. Rodrigo Carrasco
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Manuel Pedrosa
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. José M. Pascual
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Marta Navas
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Ricardo Liberal
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Rafael G. Sola
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Rodrigo Carrasco.

Additional information

Comment

Carrasco et al reported three rare cases of the lateral ventricle CM and had the systematic review of the whole reported similar cases in the literature. They analyzed the radiological findings, surgical strategies and the outcomes of these lesions. They concluded that radical surgery was still the treatment of choice, with low mortality but high neurological morbidity. This report offered the general outline of this rare subgroup of cavernoma.

But the definition of ventricle cavernoma is still not clear. Actually many lesions are the cavernoma arising from the thalamus or basal ganglia.

Intralesional hemorrhages and lesion expansion may involve the lateral wall of the ventricle and protrude into the ventricle cativity. In the case of thalamus cavernoma, it is not uncommon in the clinical experience.

Surgical treatment of the CM in that area should be carefully balanced between the outcome and the natural course. Accurate localization of the lesions with neuronavigation can offer individualized surgical approaches and avoid additional surgical trauma to the eloquent area. We agree that radical resection of the lesions is the treatment of choice. Partial resection of the lesion or biopsy is not recommended.

Ying Mao

Hua Shan Hospital, Shanghai

Rights and permissions

Reprints and permissions

About this article

Cite this article

Carrasco, R., Pedrosa, M., Pascual, J.M. et al. Cavernous angiomas of the lateral ventricles. Acta Neurochir (Wien) 151, 149–154 (2009). https://doi.org/10.1007/s00701-009-0186-8

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00701-009-0186-8

Keywords

Search

Navigation