Skip to main content

Advertisement

Log in

Surgical treatment of ventral mesencephalic cavernoma

  • Review Article
  • Published:
Acta Neurochirurgica Aims and scope Submit manuscript

Summary

The treatment of an intrinsic midbrain tumour has always been controversial due to the precarious nature of its location. We report a rare example of a cavernoma located in the ventral mesencephalon and presented clinically as Holmes’ tremor. In order to access this vital portion of midbrain, we chose a fronto-temporal trans-sylvian route via an orbito-zygomatic craniotomy. The cavernoma was removed en bloc with a longitudinal pial incision between the fronto-pontine fibers and the pyramidal tracts in the peduncle. After the operation, the tremor dramatically disappeared. Through a review and analysis of the literature, we discuss the surgical strategy for management of an anterior midbrain cavernoma. With an optimal surgical approach, fairly safe entry zones on the anterior face of the rostral brainstem may be accessible, which makes it possible for successful resection of a ventral mesencephalic cavernoma without postoperative complications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • AA Adeolu (2005) ArticleTitleSafe surgical approach to deep pontomedullary cavernoma: an iMRI-assisted resection Neurol India 53 121–122 Occurrence Handle15805675 Occurrence Handle10.4103/0028-3886.15081

    Article  PubMed  Google Scholar 

  • H Bertalanffy JM Gilsbach HR Eggert W Seeger (1991) ArticleTitleMicrosurgery of deep-seated cavernous angiomas: report of 26 cases Acta Neurochir (Wien) 108 91–99 Occurrence Handle10.1007/BF01418515 Occurrence Handle1:STN:280:DyaK3M3jtlyrtw%3D%3D

    Article  CAS  Google Scholar 

  • A Bricolo S Turazzi (1995) Surgery for gliomas and other mass lesions of the brainstem Symon (Eds) Advances and technical standards in neurosurgery NumberInSeries22 Springer Wien New York 261–341

    Google Scholar 

  • M Bruneau P Bijlenga A Reverdin B Rilliet L Regli JG Villemure F Porchet N de Tribolet (2006) ArticleTitleEarly surgery for brainstem cavernomas Acta Neurochir (Wien) 148 405–414 Occurrence Handle10.1007/s00701-005-0671-7 Occurrence Handle1:STN:280:DC%2BD287lsFKjtA%3D%3D

    Article  CAS  Google Scholar 

  • G Cantore P Missori A Santoro (1999) ArticleTitleCavernous angiomas of the brain stem. Intra-axial anatomical pitfalls and surgical strategies Surg Neurol 52 84–93 Occurrence Handle10390181 Occurrence Handle10.1016/S0090-3019(99)00036-1 Occurrence Handle1:STN:280:DyaK1MzhslSluw%3D%3D

    Article  PubMed  CAS  Google Scholar 

  • RE Clatterbuck JL Moriarity D Rigamonti (2001) ArticleTitleIntramedullary cavernoma J Neurosurg 95 156–157 Occurrence Handle11453423 Occurrence Handle1:STN:280:DC%2BD3Mvgt1CnsQ%3D%3D

    PubMed  CAS  Google Scholar 

  • A Cristini C Fischer M Sindou (2004) ArticleTitleTectal plate cavernoma-a special entity of brainstem cavernomas: case report Surg Neurol 61 474–478 Occurrence Handle15120229 Occurrence Handle10.1016/S0090-3019(03)00487-7

    Article  PubMed  Google Scholar 

  • R Fahlbusch C Strauss (1991) ArticleTitleSurgical significance of cavernous hemangioma of the brain stem Zentralbl Neurochir 52 25–32 Occurrence Handle1862673 Occurrence Handle1:STN:280:DyaK3MzitVKktA%3D%3D

    PubMed  CAS  Google Scholar 

  • R Fahlbusch C Strauss W Huk (1991) ArticleTitlePontine-mesencephalic cavernomas: indications for surgery and operative results Acta Neurochir Suppl (Wien) 53 37–41 Occurrence Handle1:STN:280:DyaK383gs1ahtA%3D%3D

    CAS  Google Scholar 

  • A Konovalov M Samii RW Porter RF Spetzler JP Houteville T Yoshimoto M Sambasivan (2000) ArticleTitleBrainstem cavernoma Surg Neurol 54 418–421 Occurrence Handle11252347 Occurrence Handle10.1016/S0090-3019(00)00347-5 Occurrence Handle1:STN:280:DC%2BD3M7ps1WlsQ%3D%3D

    Article  PubMed  CAS  Google Scholar 

  • T Kumabe M Suzuki T Yoshimoto J Suzuki (1988) ArticleTitleA case of cavernous angioma extended from the ventral part of the pons to the midbrain: subtemporal and trans-tentorial approach No Shinkei Geka 16 1193–1197 Occurrence Handle3205361 Occurrence Handle1:STN:280:DyaL1M%2Fot1Oksw%3D%3D

    PubMed  CAS  Google Scholar 

  • JL Moriarity RE Clatterbuck D Rigamonti (1999) ArticleTitleThe natural history of cavernous malformations Neurosurg Clin N Am 10 411–417 Occurrence Handle10419568 Occurrence Handle1:STN:280:DyaK1MzkvVWnsw%3D%3D

    PubMed  CAS  Google Scholar 

  • DP Muzumdar BK Misra AS Bhaduri (2000) ArticleTitlePineal region cavernoma – case report Neurol Med Chir (Tokyo) 40 372–379 Occurrence Handle10.2176/nmc.40.372 Occurrence Handle1:STN:280:DC%2BD3cvmtVSnsw%3D%3D

    Article  CAS  Google Scholar 

  • G Pendl P Vorkapic (1988) ArticleTitleMicrosurgery of midbrain lesions Acta Neurochir Suppl (Wien) 42 130–136 Occurrence Handle1:STN:280:DyaL1M%2Fks1OgsA%3D%3D

    CAS  Google Scholar 

  • M Samii R Eghbal GA Carvalho C Matthies (2001) ArticleTitleSurgical management of brainstem cavernomas J Neurosurg 95 825–832 Occurrence Handle11702873 Occurrence Handle1:STN:280:DC%2BD3MnltVOktw%3D%3D

    PubMed  CAS  Google Scholar 

  • S Sarma LN Sekhar (2002) ArticleTitleBrain stem cavernoma excised by subtemporal-infratemporal approach Br J Neurosurg 16 172–177 Occurrence Handle12046739 Occurrence Handle10.1080/02688690220131831 Occurrence Handle1:STN:280:DC%2BD38zgsFOiug%3D%3D

    Article  PubMed  CAS  Google Scholar 

  • MS Schwartz GJ Anderson MA Horgan JX Kellogg SO McMenomey JB Delashaw SuffixJr (1999) ArticleTitleQuantification of increased exposure resulting from orbital rim and orbito-zygomatic osteotomy via the frontotemporal trans-sylvian approach J Neurosurg 91 1020–1026 Occurrence Handle10584849 Occurrence Handle1:STN:280:DC%2BD3c%2FkvFGntg%3D%3D Occurrence Handle10.3171/jns.1999.91.6.1020

    Article  PubMed  CAS  Google Scholar 

  • GK Steinberg SD Chang RJ Gewirtz JR Lopez (2000) ArticleTitleMicrosurgical resection of brainstem, thalamic, and basal ganglia angiographically occult vascular malformations Neurosurgery 46 260–270 Occurrence Handle10690715 Occurrence Handle10.1097/00006123-200002000-00003 Occurrence Handle1:STN:280:DC%2BD3c7lt1Gktg%3D%3D

    Article  PubMed  CAS  Google Scholar 

  • CC Wang A Liu JT Zhang B Sun YL Zhao (2003) ArticleTitleSurgical management of brain-stem cavernous malformations: report of 137 cases Surg Neurol 59 444–454 Occurrence Handle12826334 Occurrence Handle10.1016/S0090-3019(03)00187-3

    Article  PubMed  Google Scholar 

  • T Yasui M Komiyama Y Iwai K Yamanaka Y Matsusaka T Morikawa T Ishiguro (2005) ArticleTitleA brainstem cavernoma demonstrating a dramatic, spontaneous decrease in size during follow-up: case report and review of the literature Surg Neurol 63 170–173 Occurrence Handle15680664 Occurrence Handle10.1016/j.surneu.2004.03.025

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Zhong, J., Li, ST., Xu, SQ. et al. Surgical treatment of ventral mesencephalic cavernoma. Acta Neurochir (Wien) 149, 1057–1061 (2007). https://doi.org/10.1007/s00701-007-1245-7

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00701-007-1245-7

Navigation