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Obsessive-compulsive disorder after unilateral caudate nucleus bleeding

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Summary

Obsessive compulsive disorders (OCD) may be encountered after basal ganglia lesions of various aetiologies. These lesions are usually bilateral. We report here the case of a 24 years old man who developed a pure compulsive behavior after a unilateral left-sided caudate nucleus hemorrhage due to a cavernoma. The pathophysiology of this compulsive disorder probably reflects a frontal cortex deafferentation mechanism. Behavioral, psychological and medical (serotoninergic) treatments are usually proposed but the efficacy of such therapy remains to be investigated in secondary OCD.

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Thobois, S., Jouanneau, E., Bouvard, M. et al. Obsessive-compulsive disorder after unilateral caudate nucleus bleeding. Acta Neurochir 146, 1027–1031 (2004). https://doi.org/10.1007/s00701-004-0312-6

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  • DOI: https://doi.org/10.1007/s00701-004-0312-6

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