Abstract.
The construction and electrochemical response characteristics of poly(vinyl) chloride matrix membrane sensors for menadione (vitamin K3) are described. Membranes incorporating the ion association complexes of menadione anion with bathophenanthroline nickel(II) and iron(II) as electroactive materials show linear response for menadione over the range 10−1–10−5 M with anionic slopes of 58.2–51.4 mV per concentration decade. Both sensors exhibit fast response time (20–30 s), low detection limit (2 × 10−5 M), good stability (4–6 weeks) and selectivity coefficient (10−1–10−3). Direct potentiometric determination of menadione under static and hydrodynamic mode of operations shows average accuracies of 98.8 and 98.5% with relative standard deviations of 0.6% and 1.3%, respectively. Application of the method for the determination of menadione in human plasma gives favourable results compared with those obtained by the standard spectrophotometric method.
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Received February 26, 2001. Revision October 1, 2001.
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Rizk, N. Potentiometric Determination of Menadione (Vitamin K3). Mikrochim Acta 138, 53–58 (2002). https://doi.org/10.1007/s006040200008
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DOI: https://doi.org/10.1007/s006040200008