Abstract.
A novel ion-selective sensor for procaine hydrochloride has been proposed and applied successfully to analysis of pharmaceutical preparations. The sensor is based on modification of the Ag-electrode of an AT-cut piezoelectric quartz crystal with a PVC membrane containing procaine tetraphenylborate. A linear relation between the logarithm of the response frequency and the logarithm of the procaine hydrochloride concentration was found experimentally and could be explained by combination of a modified Sauerbrey equation and the Freundlich isotherm. The detection range was from 8.3 × 10−8 to 5.0 × 10−3 M with a detection limit of 8.3 × 10−8 M. The selectivity of the sensor and the influence of experimental parameters such as solution pH and detection time were investigated.
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Received February 10, 1999. Revision October 10, 1999.
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Lei, L., Su, X., Xie, Q. et al. A Novel Ion-Selective Sensor for Procaine Hydrochloride Based on a Piezoelectric Quartz Crystal Coated with a Procaine Tetraphenylborate PVC Membrane. Mikrochim Acta 134, 63–67 (2000). https://doi.org/10.1007/s006040070055
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DOI: https://doi.org/10.1007/s006040070055