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Bi2WO6/TiO2-based visible light-driven photoelectrochemical enzyme biosensor for glucose measurement

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Abstract

Nowadays, the frequent occurrence of food adulteration makes glucose detection particularly important in food safety and quality management. The quality and taste of honey are closely related to the glucose content. However, due to the drawbacks of expensive equipment, complex operating procedures, and time-consuming processes, the application scope of traditional glucose detection methods is limited. Hence, this study developed a photoelectric chemical (PEC) sensor, which is composed of a photoactive material of bismuth tungstate (Bi2WO6) with titanium dioxide (TiO2) and glucose oxidase (GOD), for simple and rapid detection of glucose. Notably, the composites’ absorption prominently increased in the visible light region, and the photo-generated electron–hole pairs were efficiently separated by virtue of the unique nanostructure system, thus playing a crucial role in facilitating PEC activity. In the presence of dissolved oxygen, the photocurrent intensity was enhanced by H2O2 generated from glucose under electro-oxidation specifically catalyzed by GOD fixed on the modified electrode. When the working potential was 0.3 V, the changes of photocurrent response indicated that the PEC enzyme biosensor provides a low detection limit (3.8 µM), and a wide linear range (0.008–8 mM). This method has better selectivity in honey samples and broad application prospects in clinical diagnosis for future.

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Data availability

The data that support the findings of this study are available from the corresponding author upon reasonable request.

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Funding

The Science and Technology Cooperation Plan Projects of Finance of Xinjiang Production and Construction Corps Finance (2021BC010) and the President’s Fund Project of Tarim University (TDZKCX202105) provided support for this research.

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Authors and Affiliations

  1. College of Food Science and Engineering, Tarim University, Alar, China

    Xiaotian Wang, Dongliang Li, Weihua Wang, Zilong Liang, Qiujie Ma & Xiaoqin Yu

  2. Production & Construction Group Key Laboratory of Special Agr34.icultural Products Further Processing in Southern Xinjiang, Alar, China

    Weihua Wang

  3. Kazakh National Agrarian Research University, Abay 8, Almaty, Kazakhstan

    Sabira Kozykan

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  1. Xiaotian Wang
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  2. Dongliang Li
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Contributions

Xiaotian Wang: writing—review and editing, methodology, writing—original draft, formal analysis, visualization; Dongliang Li: methodology, validation, formal analysis, investigation, writing—original draft; Weihua Wang: conceptualization, supervision, methodology, funding acquisition, writing—review and editing; Sabira Kozykan: conceptualization, resources, supervision; Zilong Liang: writing—review, investigation; Qiujie Ma: supervision, investigation; Xiaoqin Yu: conceptualization and investigation.

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Correspondence to Weihua Wang.

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Xiaotian Wang and Dongliang Li make equal contributions to the present work, with the first authorship shared.

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Wang, X., Li, D., Wang, W. et al. Bi2WO6/TiO2-based visible light-driven photoelectrochemical enzyme biosensor for glucose measurement. Microchim Acta 191, 201 (2024). https://doi.org/10.1007/s00604-024-06286-4

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  • DOI: https://doi.org/10.1007/s00604-024-06286-4

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