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A direct electrochemical sensor based on covalent organic frameworks/platinum nanoparticles for the detection of ofloxacin in water

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Abstract

A direct electrochemical sensor based on covalent organic frameworks (COFs)/platinum nanoparticles (PtNPs) composite was fabricated for the detection of ofloxacin (OFX) in water. Firstly, the COF material was synthesized via the condensation reaction of 1,3,5-tris(4-aminophenyl)benzene (TAPB) with terephthalaldehyde (TPA) and integrated with PtNPs by in situ reduction. Then, TAPB-TPA-COFs/PtNPs composite was loaded onto the surface of the glassy carbon electrode (GCE) by drip coating to construct the working electrode (TAPB-TPA-COFs/PtNPs/GCE). The electrochemical performance of TAPB-TPA-COFs/PtNPs/GCE showed a significant improvement compared with that of TAPB-TPA-COFs/GCE, leading to a 3.2-fold increase in the electrochemical signal for 0.01 mM OFX. Under optimal conditions, the TAPB-TPA-COFs/PtNPs/GCE exhibited a wide linear range of 9.901 × 10−3–1.406 µM and 2.024–15.19 µM with a detection limit of 2.184 × 10−3 µM. The TAPB-TPA-COFs/PtNPs/GCE-based electrochemical sensor with excellent performance provides great potential for the rapid and trace detection of residual OFX.

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The data that support the findings of this study are available from the corresponding author, upon reasonable request.

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Acknowledgements

The authors acknowledge the support provided by the Second Tibetan Plateau Scientific Expedition, Research Program (STEP) (No. 2019QZKK020107 and 2019QZKK020107-2) and Sichuan Science and Technology Program (No. 2022YFQ0050), the Opening Research Foundation of Key Laboratory of Coarse Cereal Processing of Ministry of Agriculture and Rural Affair (No. 2020CC004), the Key Laboratory of Medicinal and Edible Plant Resources Development of Sichuan Education Department (No. 10Y202103), and the Introduction of Talent Research Start-Up Fund of Chengdu University (No. 2081920038).

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Authors and Affiliations

  1. Antibiotics Research and Re-Evaluation Key Laboratory of Sichuan Province, Chengdu University, Chengdu, 610106, China

    Juan Hao, Lijuan Huang, Li Zheng, Zhihang Yin & Kunping Liu

  2. Key Laboratory of Medicinal and Edible Plants Resources Development of Sichuan Education Department, Sichuan Industrial Institute of Antibiotics, Chengdu University, Chengdu, 610106, China

    Juan Hao, Lijuan Huang, Li Zheng, Qinghui Wang, Zhihang Yin, Huiming Li, Lingpu Jia, Wenlong Liao & Kunping Liu

  3. School of Food and Biological Engineering, Chengdu University, Chengdu, 610106, China

    Qinghui Wang, Huiming Li & Wenlong Liao

  4. Institute for Advanced Study, Chengdu University, Chengdu, 610106, China

    Lingpu Jia

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  1. Juan Hao
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  3. Li Zheng
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  4. Qinghui Wang
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Contributions

Juan Hao: Conceptualization, Formal analysis, Investigation, Methodology, Validation, Data curation, Writing—original draft. Lijuan Huang: Formal analysis, Investigation, Writing—original draft. Li Zhen: Data curation, Writing—review & editing. Qinghui Wang: Formal analysis, Investigation, Writing—review & editing. Zhihang Yin: Writing—review & editing. Huiming Li: Writing—review & editing. Lingpu Jia: Writing—review & editing. Wenlong Liao: Supervision, Writing—review & editing. Kunping Liu: Writing—review & editing, Project administration. All authors reviewed and approved the final version of the manuscript.

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Correspondence to Lingpu Jia, Wenlong Liao or Kunping Liu.

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Hao, J., Huang, L., Zheng, L. et al. A direct electrochemical sensor based on covalent organic frameworks/platinum nanoparticles for the detection of ofloxacin in water. Microchim Acta 191, 145 (2024). https://doi.org/10.1007/s00604-024-06205-7

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