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Competitive substitution in europium metal–organic gel for signal-on electrochemiluminescence detection of dipicolinic acid

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Abstract

Metal–organic gels (MOGs) emerged as an attractive luminescent soft material for electrochemiluminescence (ECL). In this work, a cathodic ECL-activated europium metal–organic gel (Eu-MOG) has been synthesized by a facile mixing of Eu3+ with 4′-(4-carboxyphenyl)-2,2′:6′,2′′-terpyridine (Hcptpy) under mild conditions. The prepared Eu-MOG is highly mesoporous for co-reactant permeation to produce an ultra-stable and high-efficient ECL, based on the antenna effect of Eu3+ coordinating with Hcptpy. Moreover, dipicolinic acid (DPA) can competitively coordinate with Eu3+ instead of water molecules, producing an enhanced ECL signal. Therefore, an ECL enhancement assay was developed for DPA detection. There was a linear relationship between the ECL intensity and the logarithmic concentration of DPA in the 0.01–1 μM range, and the detection limit is 7.35 nM. This work displays the promising application of Eu-MOG in the ECL field, opening a broad inspection for seeking a new generation of ECL luminophores.

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Data Availability

The authors declare that the data supporting this study are available within the paper. The raw data files are available from the corresponding author upon reasonable request.

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Acknowledgements

This project was financially supported by the National Natural Science Foundation of China (22004054), Natural Science Foundation of Fujian Province (2020J05163, 2021J01991), and Principal Fund of Minnan Normal University (KJ18014, L21946, KJ2023002).

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Authors and Affiliations

  1. Fujian Provincial Key Laboratory of Modern Analytical Science and Separation Technology, Fujian Provincial Key Laboratory of Pollution Monitoring and Control, College of Chemistry, Chemical Engineering and Environment, Minnan Normal University, 36 Xianqian Street, Zhangzhou, 363000, Fujian, China

    Ya Xiong, Weiqiang Yang, Shengxiu Huang, Xiaoping Chen, Qingxiang Wang & Jiancong Ni

  2. MOE Key Laboratory for Analytical Science of Food Safety and Biology, Fujian Provincial Key Laboratory of Analysis and Detection Technology for Food Safety, College of Chemistry, Fuzhou University, Fuzhou, 350116, China

    Zhenyu Lin

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  1. Ya Xiong
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  4. Xiaoping Chen
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Correspondence to Weiqiang Yang or Jiancong Ni.

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Xiong, Y., Yang, W., Huang, S. et al. Competitive substitution in europium metal–organic gel for signal-on electrochemiluminescence detection of dipicolinic acid. Microchim Acta 190, 426 (2023). https://doi.org/10.1007/s00604-023-06007-3

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