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Green photoreduction synthesis of dispersible gold nanoparticles and their direct in situ assembling in multidimensional substrates for SERS detection

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Abstract

Gold nanoparticles (AuNPs) and their composites have been applied in surface-enhanced Raman scattering (SERS) detection methods, owing to their stable and excellent surface plasmon resonance. Unfortunately, methods for synthesizing AuNPs often require harsh conditions and complicated external steps. Additionally, removing residual surfactants or unreacted reductants is critical for improving the sensitivity of SERS detection, especially when employing AuNPs-assembled multidimensional substrates. In this study, we propose a simple and green method for AuNPs synthesis via photoreduction, which does not require external surfactant additives or stabilizers. All the processes were completed within 20 min. Along this way, only methanol was employed as the electron acceptor. Based on this photoreduction synthesis strategy, AuNPs can be directly and circularly assembled in situ in multidimensional substrates for SERS detection. The removal of residual methanol was easy because of its low boiling point. This strategy was employed for the preparation of three different dimensional SERS substrates: filter paper@AuNPs, g-C3N4@AuNPs, and MIL-101(Cr)@AuNPs. The limit of detection of filter paper@AuNPs for thiabendazole SERS detection was 1.0 × 10−7 mol/L, while the limits of detection of g-C3N4@AuNPs and MIL-101(Cr)@AuNPs for malachite green SERS detection were both 5.0 × 10−11 mol/L. This strategy presents potential in AuNP doping materials and SERS detection.

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Funding

This work was supported by the National Natural Science Foundation of China (Nos. 21964008, 22104025), Guangxi Natural Science Foundation of China (Nos. 2020GXNSFBA159050, 2019GXNSFBA245100, 2020GXNSFBA297147), Guangxi science and technology base and talent special project (No. GuikeAD20238050), and the Students’ Platform for Innovation and Entrepreneurship Training Program (No. 202010601022).

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Authors and Affiliations

  1. Pharmacy School, Guilin Medical University, Guilin, 541004, People’s Republic of China

    Zhengyi Chen, Xuemei Huang, Hao Zhao, Jiaxin Wei & Fengling Li

  2. College of Food and Bioengineering, Hezhou University, Hezhou, 542899, People’s Republic of China

    Shengyong Lu, Zhi Zhang, Linjing Su & Yuhao Xiong

  3. Capital Construction Department, Guilin Medical University, Guilin, 541004, People’s Republic of China

    Kunting Yuan

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  1. Zhengyi Chen
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  2. Shengyong Lu
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  3. Zhi Zhang
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  4. Xuemei Huang
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  5. Hao Zhao
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Correspondence to Zhengyi Chen, Linjing Su or Yuhao Xiong.

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Chen, Z., Lu, S., Zhang, Z. et al. Green photoreduction synthesis of dispersible gold nanoparticles and their direct in situ assembling in multidimensional substrates for SERS detection. Microchim Acta 189, 275 (2022). https://doi.org/10.1007/s00604-022-05379-2

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