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Photonic crystal sensor for melamine based on magnetic molecularly imprinted nanoparticles self-assembled with an amphiphilic random copolymer

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Abstract

Magnetic molecularly imprinted nanoparticles (MMINPs) were obtained with a one-step process through miniemulsion self-assembly using an amphiphilic random copolymer as both an emulsifier and MMINP coating, oleic acid–modified magnetite nanoparticles as magnetic cores, and melamine (MEL) as the template molecule. MMINPs were assembled under an external magnetic field to construct photonic crystal (PC) sensor for naked-eye detection of MEL. The MMINPs were characterized by FT-IR, TEM, TGA, and VSM. The analytical performances of the magnetic molecularly imprinted PC sensor for MEL (MEL-MMIPCs) were investigated with respect to sensitivity, response time, selectivity, and stability. As the MEL concentration increases from 1.0 to 1.0 × 106 μg/l, the reflection wavelength of MEL-MMIPCs shifted from 497 to 709 nm, and was linear with the logarithm of MEL concentration in this range. The detection limit was 0.21 μg/l (S/N = 3) and response time was within 30 s. The MEL-MMIPC sensor had an imprinting factor of 5.09, and selectivity factors for the analogs cyanuric acid and atrazine were 8.76 and 5.75, respectively, indicating the high sensitivity and selectivity. After 10 cycles of elution/response, MEL-MMIPCs still had a good ability to recognize MEL.

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References

  1. Zhu H, Kannan K (2020) Determination of melamine and its derivatives in textiles and infant clothing purchased in the United States. Sci Total Environ 710(C):136396 https://doi.org/10.1016/j.scitotenv.2019.136396

  2. Rovina K, Siddiquee S (2015) A review of recent advances in melamine detection techniques. J Food Compos Anal 43:25–38. https://doi.org/10.1016/j.jfca.2015.04.008

    Article  CAS  Google Scholar 

  3. Limin L, Shong CW (2021) Rapid and sensitive SERS detection of melamine in milk using Ag nanocube array substrate coupled with multivariate analysis. Food Chem 357:129717–129717. https://doi.org/10.1016/j.foodchem.2021.129717

    Article  CAS  Google Scholar 

  4. Zhenhua Z (2019) The Sanlu milk powder case: triggering a food safety crisis in the dairy industry[J] Fangyuan (Z1):96–99

  5. GarcíaLópezFernando J, Quereda C (2011) Melamine toxicity: one more culprit in calcium kidney lithiasis.[J]. Kidney Int 80(7):694–6. https://doi.org/10.1038/ki.2011.174

    Article  CAS  Google Scholar 

  6. Mohit T, et al (2021) Au nanoparticles decorated ZnO/ZnFe2O4 composite SERS-active substrate for melamine detection. Talanta 236https://doi.org/10.1016/j.talanta.2021.122819

  7. Ritota M, Manzi P (2018) Melamine detection in milk and dairy products: traditional analytical methods and recent developments. Food Anal Methods 11:128–147. https://doi.org/10.1007/s12161-017-0984-1

    Article  Google Scholar 

  8. Lutter P et al (2011) Screening and confirmatory methods for the determination of melamine in cow’s milk and milk-based powdered infant formula: validation and proficiency-tests of ELISA, HPLC-UV, GC-MS and LC-MS/MS [J]. Food Control 22(6):903–913. https://doi.org/10.1016/j.foodcont.2010.11.022

    Article  CAS  Google Scholar 

  9. Quang T, Hieu (2021) Validation of the method for determination of melamine and investigation its trace in milk from Vietnam by LC-MS/MS. Asian J Appl Chem Res 13-19https://doi.org/10.9734/ajacr/2021/v8i130182

  10. Wu Y, Zhang Y (2013) Analytical chemistry, toxicology, epidemiology and health impact assessment of melamine in infant formula: recent progress and developments. Food Chem Toxicol 56:325–335. https://doi.org/10.1016/j.fct.2013.02.044

    Article  CAS  PubMed  Google Scholar 

  11. Strashnov I, Karunarathna NB, Fernando BR, Dissanayake C, Binduhewa KM (2021) An isotope dilution liquid chromatography-mass spectrometry method for detection of melamine in milk powder. Food Addit Contam Part A, Chem Anal Control Exp Risk Assess 1–12 Advance online publication. https://doi.org/10.1080/19440049.2021.1937709

  12. Haghi E, Alimohammadi M, Shakoori A, Razeghi F, Sadighara P (2018) Measurement of melamine migration from melamine-ware products by designed HPLC method and the effect of food-type on the level of migration. Interdiscip Toxicol 11(4):316–320. https://doi.org/10.2478/intox-2018-0031

    Article  CAS  PubMed  Google Scholar 

  13. Šlampová A, Kubáň P (2016) Rapid determination of meldonium in urine samples by capillary electrophoresis with capacitively coupled contactless conductivity detection. J Chromatogr A 1468:236–240. https://doi.org/10.1016/j.chroma.2016.09.027

    Article  CAS  PubMed  Google Scholar 

  14. Xiong Z, Chen X, Liou P et al (2017) Development of nanofibrillated cellulose coated with gold nanoparticles for measurement of melamine by SERS. Cellulose 24:2801–2811. https://doi.org/10.1007/s10570-017-1297-7

    Article  CAS  Google Scholar 

  15. Yalan Z et al (2020) (2020) Self-healable magnetic structural color hydrogels. ACS Appl Mater Interfaces 12(6):7486–7493. https://doi.org/10.1021/acsami.9b22579

    Article  CAS  Google Scholar 

  16. Zhiwei Li et al (2019) Magnetic assembly of nanocubes for orientation-dependent photonic responses. Nano Lett 19(9):6673–6680. https://doi.org/10.1021/acs.nanolett.9b02984

    Article  CAS  Google Scholar 

  17. Wang L, Wang L (2021) High selectivity sensing of bovine serum albumin: the combination of glass nanopore and molecularly imprinted technology. Biosens Bioelectron 178:113056. https://doi.org/10.1016/j.bios.2021.113056

    Article  CAS  PubMed  Google Scholar 

  18. Arabi M (2020) Strategies of molecular imprinting-based solid-phase extraction prior to chromatographic analysis. TrAC, Trends Anal Chem 128:115923. https://doi.org/10.1016/j.trac.2020.115923

    Article  CAS  Google Scholar 

  19. Chen L (2016) Molecular imprinting: perspectives and applications. Chem Soc Rev 45:2137–2211. https://doi.org/10.1039/C6CS00061D

    Article  CAS  PubMed  Google Scholar 

  20. Arabi M et al (2020) Label-free SERS detection of Raman-Inactive protein biomarkers by Raman reporter indicator: toward ultrasensitivity and universality. Biosens Bioelectron 174:112825. https://doi.org/10.1016/j.bios.2020.112825

    Article  CAS  PubMed  Google Scholar 

  21. C Chehasan et al. (2021) Molecularly imprinted polymer nanogel-based fluorescence sensing of pork contamination in halal meat extracts. Biosens Bioelectron 172https://doi.org/10.1016/j.bios.2020.112775

  22. You A, Cao Y, Cao G (2017) Facile and convenient fabrication of color-controlled colloidal magnetically assembled photonic crystals. Chem Res Chin Univ 33:525–529. https://doi.org/10.1007/s40242-017-6310-z

    Article  CAS  Google Scholar 

  23. Shang M, Ni X, Jiasheng Xu, Ca Y (2019) Amphiphilic copolymer self-assembly of magnetic nanoparticles for construction of magnetically responsive photonic crystals based on steric hindrance. RSC Adv 9:41280–41286. https://doi.org/10.1039/C9RA08962D

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  24. Cong L, Kuncheng Q, Zhikuan X, Yubin X, Wei Z (2020) Optimizing the protein removal process of Smilax glabra polysaccharide by response surface methodology [J]. Subtrop Plant Sci 49(04):264–269

    Google Scholar 

  25. Liancai Z, Shijin T, Li Z (2020) The teaching practice and methodology of protein content determination by Coomassie brilliant blue G250 method [J]. Educ Teach Forum 23:266–269

    Google Scholar 

  26. Eagambaram M et al (2018) Core-shell nanostructured Fe3O4-poly (styrene- co -vinylbenzyl chloride) grafted PPI dendrimers stabilized with AuNPs/PdNPs for efficient nuclease activity [J]. ACS Omega 3(10):13685–13693. https://doi.org/10.1021/acsomega.8b01326

    Article  CAS  Google Scholar 

  27. Luo W, Ma H, Mou F et al (2014) Steric-repulsion-based magnetically responsive photonic crystals.[J]. Adv Mater 26(7):1058–1064. https://doi.org/10.1002/adma.201304134

    Article  CAS  PubMed  Google Scholar 

  28. Xu L, Li D, Jiang B et al (2019) Melamine-mediated base mismatch for label-free and amplified sensitive fluorescent detection of melamine in milk. Food Anal Methods 12:1255–1261. https://doi.org/10.1007/s12161-019-01465-z

    Article  Google Scholar 

  29. An J, Li L, Ding Y, Hu W, Chen H (2019) A novel molecularly imprinted electrochemical sensor based on Prussian blue analogue generated by iron metal organic frameworks for highly sensitive detection of melamine. Electrochimica Acta 326:134946. https://doi.org/10.1016/j.electacta.2019.134946

    Article  CAS  Google Scholar 

  30. Du, Jianxiu, Wang, Yadi, Zhang, Weimin (2015) Gold nanoparticles-based chemiluminescence resonance energy transfer for ultrasensitive detection of melamine [J]. Spectrochim Acta Part A. Mol Biomol Spectrosc 149A698–702 https://doi.org/10.1016/j.saa.2015.04.067

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Authors and Affiliations

  1. School of Chemical and Material Engineering, Jiangnan University, 1800 Lihu Road, Wuxi, 214122, China

    Tingyi Hu, Jiasheng Xu, Meng Shang, Qiang Zhao & Yuhua Cao

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  1. Tingyi Hu
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  2. Jiasheng Xu
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  3. Meng Shang
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Correspondence to Yuhua Cao.

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Hu, T., Xu, J., Shang, M. et al. Photonic crystal sensor for melamine based on magnetic molecularly imprinted nanoparticles self-assembled with an amphiphilic random copolymer. Microchim Acta 189, 215 (2022). https://doi.org/10.1007/s00604-022-05300-x

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