Skip to main content
SpringerLink
Log in

Electrochemical dopamine sensor based on bi-metallic Co/Zn porphyrin metal–organic framework

  • Original Paper
  • Published:
Microchimica Acta Aims and scope Submit manuscript

Abstract

Integrating other metal ions into mono-metallic metal–organic framework (MOF) to form bi-metallic MOF is an effective strategy to enhance the performance of MOFs from the internal structure. In this study, two-dimensional (2D) cobalt/zinc-porphyrin (Co/Zn-TCPP) MOF nanomaterials with different Co/Zn molar ratios were synthesised using a simple surfactant-assisted method, and novel dopamine (DA) sensing methods were constructed based on these materials. The characterisation results showed that all MOF with different Co/Zn molar ratios presented a nanofilm, and the Co and Zn elements were uniformly distributed. All sensors based on CoxZn100−x-TCPP had a certain catalytic performance to DA. Among them, the sensor based on CO25Zn75-TCPP showed the strongest signal response, indicating that the catalytic performance of MOF on DA can be adjusted by changing the Co/Zn molar ratio. The doping of metal ions improves the chemical environment of the pores, and increases the types and spatial arrangement of the active sites of the MOF, which is beneficial to the electron transfer and exchange with DA; Co2+ and Zn2+ active centres have a synergistic promotion effect, so the catalytic activity of MOF is significantly improved. The linear range at the potential of 0.1 V based on Co25Zn75-TCPP for DA was 5 nM–177.8 μM, with a detection limit of 1.67 nM (S/N = 3). The sensor exhibited a good selectivity for detecting DA. This research is expected to provide new ideas and references for constructing high-performance sensing interfaces and platforms.

Graphical abstract

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Scheme 1
Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7

Similar content being viewed by others

References

  1. Yu XY, Yu L, Wu HB, Lou XW (2015) Formation of nickel sulfide nanoframes from metal–organic frameworks with enhanced pseudocapacitive and electrocatalytic properties. Angew Chem 127:5421–5425

    Article  Google Scholar 

  2. Ma J, Chen G, Bai W, Zheng J (2020) Amplified electrochemical hydrogen peroxide sensing based on Cu-porphyrin metal–organic framework nanofilm and G–quadruplex–hemin DNAzyme. ACS Appl Mater Interfaces 12:58105–58112

    Article  CAS  PubMed  Google Scholar 

  3. Wang B, Zhao M, Li L, Huang Y, Zhang X, Guo C, Zhang Z, Cheng H, Liu W, Shang J, Jin J, Sun X, Liu J, Zhang H (2020) Ultra–thin metal–organic framework nanoribbons. Natl Sci Rev 7:46–52

    Article  CAS  PubMed  Google Scholar 

  4. Bai W, Li S, Ma J, Cao W, Zheng J (2019) Ultrathin 2D metal–organic framework (nanosheets and nanofilms) –based xD–2D hybrid nanostructures as biomimetic enzymes and supercapacitors. J Am Chem Soc 7:9086–9098

    CAS  Google Scholar 

  5. Liu W, Yin XB (2016) Metal–organic frameworks for electrochemical applications, Trac-Trends. Anal Chem 75:86–96

    CAS  Google Scholar 

  6. Masoomi MY, Morsali A, Dhakshinamoorthy A, Garcia H (2019) Mixed–metal MOFs: unique opportunities in metal–organic framework (MOF) functionality and design. Angew Chem 58:15188–15205

    Article  CAS  Google Scholar 

  7. Queen WL, Hudson MR, Bloch ED, Mason JA, Gonzalez MI, Lee JS, Gygi D, Howe JD, Lee K, Darwish TA, James M, Peterson VK, Teat SJ, Smit B, Neaton JB, Long JR, Brown CM (2014) Comprehensive study of carbon dioxide adsorption in the metal–organic frameworks M2(dobdc) (M=Mg, Mn, Fe Co, Ni, Cu, Zn). Chem Sci 5:4569

    Article  CAS  Google Scholar 

  8. Niu X, Li X, Lyu Z, Pan J, Ding S, Ruan X, Zhu W, Du D, Lin Y (2020) Metal–organic framework based nanozymes: promising materials for biochemical analysis. Chem Commun 56:11338–11353

    Article  CAS  Google Scholar 

  9. Fu Y, Xu L, Shen H, Yang H, Zhang F, Zhu W, Fan M (2016) Tunable catalytic properties of multi–metal–organic frameworks for aerobic styrene oxidation. Chem Commun 299:135–141

    CAS  Google Scholar 

  10. Kaur G, Rai RK, Tyagi D, Yao X, Li PZ, Yang XC, Zhao YL, Xu Q, Singh SK (2016) Room–temperature synthesis of bimetallic Co–Zn based zeolitic imidazolate frameworks in water for enhanced CO2 and H2 uptakes. J Mater Chem A 4:14932

    Article  CAS  Google Scholar 

  11. Ji L, Jin Y, Wu K, Wan C, Yang N, Tang Y (2018) Morphology–dependent electrochemical sensing performance of metal (Ni Co, Zn) –organic frameworks. Anal Chim Acta 1031:60–66

    Article  CAS  PubMed  Google Scholar 

  12. Ketrat S, Maihom T, Wannakao S, Probst M, Nokbin S, Limtrakul J (2017) Coordinatively unsaturated metal–organic frameworks M3(btc)2 (M = Cr, Fe Co, Ni, Cu, and Zn) catalyzing the oxidation of CO by N2O: insight from DFT calculations. Inorg Chem 56:14005–14012

    Article  CAS  PubMed  Google Scholar 

  13. Li R, Ren X, Ma H, Feng X, Lin Z, Li X, Hu C, Wang B (2014) Nickel–substituted zeolitic imidazolate frameworks for time–resolved alcohol sensing and photocatalysis under visible light. J Mater Chem A 2:5724–5729

    Article  CAS  Google Scholar 

  14. Jiang ZW, Zou YC, Zhao TT, Zhen SJ, Li YF, Huang CZ (2020) Controllable synthesis of porphyrin–based 2D lanthanide metal–organic frameworks with thickness– and metal–node–dependent photocatalytic performance. Angew Chem 132:3326–3332

    Article  Google Scholar 

  15. Zhu W, Yang Y, Jin Q, Chao Y, Tian L, Liu J, Dong Z, Liu Z (2019) Two–dimensional metal–organic–framework as a unique theranostic nano–platform for nuclear imaging and chemo-photodynamic cancer therapy. Nano Res 12:1307–1312

    Article  CAS  Google Scholar 

  16. Chen J, Lin S, Zhao D, Guan L, Hu Y, Wang Y, Lin K, Zhu Y (2020) Palladium nanocrystals–engineered metal–organic frameworks for enhanced tumor inhibition by synergistic hydrogen/photodynamic therapy. Adv Funct Mater 31:2006853

    Article  Google Scholar 

  17. Khan AF, Brownson DA, Randviir EP, Smith GC, Banks CE (2016) 2D Hexagonal Boron Nitride (2D–hBN) Explored for the electrochemical sensing of dopamine. Anal Chem 88:9729–9737

    Article  CAS  PubMed  Google Scholar 

  18. Zhang W, Liu L, Li Y, Wang D, Ma H, Ren H, Shi Y, Han Y, Ye B (2018) Electrochemical sensing platform based on the biomass–derived microporous carbons for simultaneous determination of ascorbic acid, dopamine, and uric acid. Biosens Bioelectron 121:96–103

    Article  CAS  PubMed  Google Scholar 

  19. Kavanagh DJ, Andrade J, May J (2005) Imaginary relish and exquisite torture: the elaborated intrusion theory of desire. Psychol Rev 112:446–467

    Article  PubMed  Google Scholar 

  20. Franken IHA, Booij J, van den Brink W (2005) The role of dopamine in human addiction: from reward to motivated attention. Eur J Pharmacol 526:199–206

    Article  CAS  PubMed  Google Scholar 

  21. Beaulieu JM, Gainetdinov RR (2011) The physiology, signaling, and pharmacology of dopamine receptors. Pharmacol Rev 63:182–217

    Article  CAS  PubMed  Google Scholar 

  22. Berke JD, Hyman SE (2000) addiction, dopamine, and the molecular mechanisms of memory. Neuron 25:515–532

    Article  CAS  PubMed  Google Scholar 

  23. Ramachandran A, Panda S, Yesodha SK (2018) Physiological level and selective electrochemical sensing of dopamine by a solution processable graphene and its enhanced sensing property in general. Sens Actuators B Chem 256:488–497

    Article  CAS  Google Scholar 

  24. Ramakrishnan S, Pradeep KR, Raghul A, Senthilkumar R, Rangarajan M, Kothurkar NK (2015) One-step synthesis of Pt-decorated graphene–carbon nanotubes for the electrochemical sensing of dopamine, uric acid and ascorbic acid. Anal Methods 7:779–786

    Article  CAS  Google Scholar 

  25. Zhao M, Li Z, Zhang X, Yu J, Ding Y, Li H, Ma Y (2020) Employing the interfacial barrier of P–rGO/ZnO microspheres for improving the electrochemical sensing performance to dopamine Sens. Actuators B Chem 309:127757

    Article  CAS  Google Scholar 

  26. Yang H, Zhao J, Qiu M, Sun P, Han D, Niu L, Cui G (2019) Hierarchical bi-continuous Pt decorated nanoporous Au–Sn alloy on carbon fiber paper for ascorbic acid, dopamine and uric acid simultaneous sensing. Biosens Bioelectron 124:191–198

    Article  PubMed  Google Scholar 

  27. Sha T, Li X, Liu J, Sun M, Wang N, Bo X, Guo Y, Hu Z, Zhou M (2018) Biomass waste derived carbon nanoballs aggregation networks-based aerogels as electrode material for electrochemical sensing. Sens Actuators B Chem 277:195–204

    Article  CAS  Google Scholar 

  28. Xue C, Han Q, Wang Y, Wu J, Wen T, Wang R, Hong J, Zhou X, Jiang H (2013) Amperometric detection of dopamine in human serum by electrochemical sensor based on gold nanoparticles doped molecularly imprinted polymers. Biosens Bioelectron 49:199–203

    Article  CAS  PubMed  Google Scholar 

  29. Song Y, Han J, Xu L, Miao L, Peng C, Wang L (2019) A dopamine–imprinted chitosan film/porous ZnO NPs@carbon nanospheres/macroporous carbon for electrochemical sensing dopamine sens. Actuators B Chem 298:126949

    Article  CAS  Google Scholar 

  30. Bas SZ, Cummins C, Selkirk A, Borah D, Ozmen M, Morris MA (2019) A novel electrochemical sensor based on metal ion infiltrated block copolymer thin films for sensitive and selective determination of dopamine. ACS Appl Nano Mater 2:7311–7318

    Article  CAS  Google Scholar 

  31. Ma J, Bai W, Zheng J (2019) Non-enzymatic electrochemical hydrogen peroxide sensing using a nanocomposite prepared from silver nanoparticles and copper (II) –porphyrin derived metal–organic framework nanosheets. Microchim Acta 186:482

    Article  Google Scholar 

  32. Ma J, Zheng J (2020) Voltammetric determination of hydrogen peroxide using AuCu nanoparticles attached on polypyrrole–modified 2D metal–organic framework nanosheets. Microchim Acta 187:389

    Article  CAS  Google Scholar 

  33. Wang Y, Zhao M, Ping J, Chen B, Cao X, Huang Y, Tan C, Ma Q, Wu S, Yu Y, Lu Q, Chen J, Zhao W, Ying Y, Zhang H (2016) Bioinspired design of ultrathin 2D bimetallic metal–organic-framework nanosheets used as biomimetic enzymes. Adv Mater 28:4149–4155

    Article  CAS  PubMed  Google Scholar 

  34. Xie F, Cao X, Qu F, Asiri AM, Sun X (2018) Cobalt nitride nanowire array as an efficient electrochemical sensor for glucose and H2O2 detection. Sens Actuators B Chem 255:1254–1261

    Article  CAS  Google Scholar 

  35. Ye L, Gao Y, Cao S, Chen H, Yao Y, Hou J, Sun L (2018) Assembly of highly efficient photocatalytic CO2 conversion systems with ultrathin two-dimensional metal–organic framework nanosheets. Appl Catal B-Environ 227:54–60

    Article  CAS  Google Scholar 

  36. Zhang P, Zhang L, Zhao G, Feng F (2012) A highly sensitive nonenzymatic glucose sensor based on CuO nanowires. Microchim Acta 176:411–417

    Article  CAS  Google Scholar 

  37. Cui HF, Ye JS, Zhang WD, Li CM, Luong JHT, Sheu FS (2007) Selective and sensitive electrochemical detection of glucose in neutral solution using platinum–lead alloy nanoparticle carbon nanotube nanocomposites. Anal Chim Acta 594:175–183

    Article  CAS  PubMed  Google Scholar 

  38. Huang Q, Lin X, Tong L, Tong QX (2020) graphene quantum dots/multiwalled carbon nanotubes composite-based electrochemical sensor for detecting dopamine release from living cells. ACS Sustainable Chem Eng 8:1644–1650

    Article  Google Scholar 

  39. Kumar M, Swamy BEK, Reddy S, Zhao W, Chetana S, Kumar VG (2019) ZnO/functionalized MWCNT and Ag/functionalized MWCNT modified carbon paste electrodes for the determination of dopamine, paracetamol and folic acid. J Electroanal Chem 835:96–105

    Article  CAS  Google Scholar 

  40. Rajaei M, Foroughi MM, Jahani S, Zandi MS, Nadiki HH (2019) Sensitive detection of morphine in the presence of dopamine with La3+ doped fern-like CuO nanoleaves/MWCNTs modified carbon paste electrode. J Mol Liq 284:462–472

    Article  CAS  Google Scholar 

  41. Zou J, Wu S, Liu Y, Sun Y, Cao Y, Hsu JP, Wee ATS, Jiang J (2018) An ultra-sensitive electrochemical sensor based on 2D g-C3N4/CuO nanocomposites for dopamine detection. Carbon 130:652–663

    Article  CAS  Google Scholar 

  42. Shu Y, Li Z, Yang Y, Tan J, Liu Z, Shi Y, Ye C, Gao Q (2021) Isolated cobalt atoms on N-doped carbon as nanozymes for hydrogen peroxide and dopamine detection. ACS Appl Nano Mater 4:7954–7962

    Article  CAS  Google Scholar 

  43. Zhang Y, Wang J, Xu M (2010) A sensitive DNA biosensor fabricated with gold nanoparticles/poly(p-aminobenzoic acid)/carbon nanotubes modified electrode. Colloids Surf B 75:179–185

    Article  CAS  Google Scholar 

  44. Khan AF, Brownson DAC, Randviir EP, Smith GC, Banks CE (2016) 2D hexagonal boron nitride (2D-hBN) Explored for the Electrochemical Sensing of Dopamine. Anal Chem 88:9729–9737

    Article  CAS  PubMed  Google Scholar 

  45. Sivasubramanian R, Biji P (2016) Preparation of copper (I) oxide nanohexagon decorated reduced graphene oxide nanocomposite and its application in electrochemical sensing of dopamine. Mater Sci Eng B 210:10–18

    Article  CAS  Google Scholar 

  46. Zhang W, Liu L, Li Y, Wang D, Ma H, Ren H, Shi Y, Han Y, Ye BC (2018) Electrochemical sensing platform based on the biomass-derived microporous carbons for simultaneous determination of ascorbic acid, dopamine, and uric acid. Biosens Bioelectron 121:96–103

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

The authors gratefully acknowledge the financial support of this project by the National Natural Science Foundation of China (No. 21575113) and the Natural Science Foundation of Shaanxi Province (No. 2018JQ2029).

Funding

National Natural Science Foundation of China, 21575113, Jianbin Zheng, Natural Science Foundation of Shaanxi Province, 2018JQ2029, Wushuang Bai.

Author information

Authors and Affiliations

  1. College of Chemistry & Materials Science, Shaanxi Provincial Key Laboratory of Electroanalytical Chemistry, Northwest University, Xi’an, 710127, Shaanxi, China

    Junping Ma, Xiaoli Liu & Jianbin Zheng

  2. College of Food Science and Engineering, Shaanxi Provincial Key Laboratory of Electroanalytical Chemistry, Northwest University, Xi’an, 710169, Shaanxi, China

    Wushuang Bai

Authors
  1. Junping Ma
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Wushuang Bai
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Xiaoli Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Jianbin Zheng
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Wushuang Bai or Jianbin Zheng.

Ethics declarations

Competing Interests

The authors declare no competing interests.

Additional information

Publisher's note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (DOC 6704 KB)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Ma, J., Bai, W., Liu, X. et al. Electrochemical dopamine sensor based on bi-metallic Co/Zn porphyrin metal–organic framework. Microchim Acta 189, 20 (2022). https://doi.org/10.1007/s00604-021-05122-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s00604-021-05122-3

Keywords

Search

Navigation