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Optimization of localized surface plasmon resonance hot spots in surface-enhanced infrared absorption spectroscopy aluminum substrate as an optical sensor coupled to chemometric tools for the purity assay of quinary mixtures

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Abstract

Surface-enhanced infrared absorption spectroscopy offers an alternative to conventional IR spectroscopy and utilizes the signal enhancement exerted by the plasmon resonance of nanostructured metal thin films. Citrate-capped silver nanoparticles were prepared in a single-step method, and their morphology was identified using transmission electron microscopy, scanning electron microscopy, ultraviolet/visible spectrophotometry, and Zetasizer. The nanoparticles generated were deposited on the surface of cheap aluminum slides for different durations aiming for the selection of the best time producing a thin film, suitable to act as a lab-on-a-chip SEIRA substrate. These substrates were coupled to partial least squares regression tools for simultaneous resolving of the quinary mixture in commercial dosage forms of bisoprolol, perindopril, bisoprolol acid degradation product, bisoprolol alkali degradation product, and perindoprilat in concentration ranges of 15–75, 60–300, 15–55, 12–60, and 20–80 μg/mL with limits of detection values of 0.69, 3.43, 0.97, 1.25, and 1.09 μg/mL, respectively. Overall, we could demostrate that the localized surface plasmon resonance sensor coupled to chemometrics provides cheap, simple, selective, multiplex, rapid, and molecular specific procedures for impurity detection, which would be beneficial in many applications for quality control and quality accuracy of active pharmaceutical ingredients.

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References

  1. Sala A, Anderson D, Brennan P, Butler H, Cameron J, Jenkinson M, Rinaldi C, Theakstone A, Baker M (2020) Biofluid diagnostics by FTIR spectroscopy: a platform technology for cancer detection. Cancer Lett 477:122–130

    Article  CAS  Google Scholar 

  2. Eid SM, El-Rahman MKA, Elghobashy MR, Kelani KM (2017) Attenuated total reflectance Fourier transformation infrared spectroscopy fingerprinted online monitoring of the kinetics of circulating butyrylcholinesterase enzyme during metabolism of bambuterol. Anal Chim Acta

  3. Granada E, Eguia P, Vilan J, Comesana J, Comesana R (2012) FTIR quantitative analysis technique for gases. Application in a biomass thermochemical process. Renew Energy 41:416–421

    Article  CAS  Google Scholar 

  4. Lin M, Song Y, Lo P, Hsu C, Lin A, Huang E, Chiang H (2019) Quantitative analysis of calcium oxalate hydrate urinary stones using FTIR and 950/912 cm(−1) peak ratio. Vib Spectrosc 102:85–90

    Article  CAS  Google Scholar 

  5. Reig F, Adelantado J, Moreno M (2002) FTIR quantitative analysis of calcium carbonate (calcite) and silica (quartz) mixtures using the constant ratio method. Application to geological samples. Talanta 58:811–821

    Article  CAS  Google Scholar 

  6. Chophi R, Sharma S, Singh R (2020) Forensic analysis of red lipsticks using ATR-FTIR spectroscopy and chemometrics, forensic chemistry. 17

  7. Kelani K, Rezk M, Monir H, ElSherbiny M, Eid S (2020) FTIR combined with chemometric tools (fingerprinting spectroscopy) in comparison to HPLC: which strategy offers more opportunities as a green analytical chemistry technique for pharmaceutical analysis. Anal Methods 12:5893–5907

    Article  CAS  Google Scholar 

  8. Fanelli S, Zimmermann A, Totoli E, Salgado H (2018) FTIR spectrophotometry as a green tool for quantitative analysis of drugs: practical application to amoxicillin, journal of chemistry. 2018

  9. Eid S, Kelani K, Badran O, Rezk M, Elghobashy M (2020) Surface enhanced infrared absorption spectroscopy (SEIRA) as a green analytical chemistry approach: coating of recycled aluminum TLC sheets with citrate capped silver nanoparticles for chemometric quantitative analysis of ternary mixtures as a green alternative to the traditional methods. Anal Chim Acta 1117:60–73

    Article  CAS  Google Scholar 

  10. Wanzenböck HD, Mizaikoff B, Weissenbacher N, Kellner R (1997) Multiple internal reflection in surface enhanced infrared absorption spectroscopy (SEIRA) and its significance for various analyte groups. J Mol Struct 410-411:535–538

    Article  Google Scholar 

  11. Mayerhöfer TG, Pipa AV, Popp J (2019) Beer's law-why integrated absorbance depends linearly on concentration. Chemphyschem 20:2748–2753

    Article  Google Scholar 

  12. Algethami F, Eid S, Kelani K, Elghobashy M, Abd El-Rahman M (2020) Chemical fingerprinting and quantitative monitoring of the doping drugs bambuterol and terbutaline in human urine samples using ATR-FTIR coupled with a PLSR chemometric tool. RSC Adv 10:7146–7154

    Article  CAS  Google Scholar 

  13. Hartstein A, Kirtley JR, Tsang JC (1980) Enhancement of the infrared absorption from molecular monolayers with thin metal overlayers. Phys Rev Lett 45:201–204

    Article  CAS  Google Scholar 

  14. Aroca R, RodriguezLlorente S (1997) Surface-enhanced vibrational spectroscopy. J Mol Struct 408:17–22

    Article  Google Scholar 

  15. Baia M, Toderas F, Baia L, Maniu D, Astilean S (2009) Multilayer structures of self-assembled gold nanoparticles as a unique SERS and SEIRA substrate. Chemphyschem 10:1106–1111

    Article  CAS  Google Scholar 

  16. Bibikova O, Haas J, Lopez-Lorente A, Popov A, Kinnunen M, Meglinski I, Mizaikoff B (2017) Towards enhanced optical sensor performance: SEIRA and SERS with plasmonic nanostars. Analyst 142:951–958

    Article  CAS  Google Scholar 

  17. Wedlich RC, Pires A, Fazzino L, Fransen JM (2013) Good laboratory practice. Part 3. Implementing good laboratory practice in the analytical lab. J Chem Educ 90:862–865

    Article  CAS  Google Scholar 

  18. Hassan SA, Nashat NW, Elghobashy MR, Abbas SS, Moustafa AA (2020) Stability-indicating RP-HPLC and CE methods for simultaneous determination of bisoprolol and perindopril in pharmaceutical formulation: a comparative study. J Chromatogr Sci 58:747–758

    Article  Google Scholar 

  19. Finkel R, Clark MA, Cubeddu LX (2009) Pharmacology. Lippincott Williams & Wilkins

  20. A.C. Cartwright, The British pharmacopoeia, 1864 to 2014, 2016

    Book  Google Scholar 

  21. Shaikh S, Thusleem OA, Muneera MS, Akmal J, Kondaguli AV, Ruckmani K (2008) A simple and rapid high-performance liquid chromatographic method for the determination of bisoprolol fumarate and hydrochlorothiazide in a tablet dosage form. J Pharm Biomed Anal 48:1055–1057

    Article  CAS  Google Scholar 

  22. Zaazaa HE, Abbas SS, Essam HAM, El-Bardicy MG (2012) Validated chromatographic methods for determination of perindopril and amlodipine in pharmaceutical formulation in the presence of their degradation products. J Chromatogr Sci 51:533–543

    Article  Google Scholar 

  23. Gkogkou D, Shaykhutdinov T, Kratz C, Oates TWH, Hildebrandt P, Weidinger IM, Ly KH, Esser N, Hinrichs K (2019) Gradient metal nanoislands as a unified surface enhanced Raman scattering and surface enhanced infrared absorption platform for analytics. Analyst 144:5271–5276

    Article  CAS  Google Scholar 

  24. Brereton RG (2003) Chemometrics: data analysis for the laboratory and chemical plant. Wiley

  25. Eid SM (2020) Indirect nano-sensing approach: a universal potentiometric silver ion selective sensor for inline quantitative profiling of the kinetics and thermodynamics of formation and decay of silver nanoparticles, Talanta, 218

  26. Bastús NG, Merkoçi F, Piella J, Puntes V (2014) Synthesis of highly monodisperse citrate-stabilized silver nanoparticles of up to 200 nm: kinetic control and catalytic properties. Chem Mater 26:2836–2846

    Article  Google Scholar 

  27. Agnihotri S, Mukherji S, Mukherji S (2013) Immobilized silver nanoparticles enhance contact killing and show highest efficacy: elucidation of the mechanism of bactericidal action of silver. Nanoscale 5

  28. Pillai ZS, Kamat PV (2004) What factors control the size and shape of silver nanoparticles in the citrate ion reduction method? J Phys Chem B 108:945–951

    Article  CAS  Google Scholar 

  29. Kurrey R, Deb MK, Shrivas K (2019) Surface enhanced infra-red spectroscopy with modified silver nanoparticles (AgNPs) for detection of quaternary ammonium cationic surfactants. New J Chem 43:8109–8121

    Article  CAS  Google Scholar 

  30. Manojkumar K, Sivaramakrishna A, Vijayakrishna K (2016) A short review on stable metal nanoparticles using ionic liquids, supported ionic liquids, and poly(ionic liquids). J Nanopart Res 18

  31. Kraynov A, Muller T, Handy S (2011) Concepts for the stabilization of metal nanoparticles in ionic liquids. Appl Ionic Liq Sci Technol:235–260

  32. Otto A (2005) The 'chemical' (electronic) contribution to surface-enhanced Raman scattering. J Raman Spectrosc 36:497–509

    Article  CAS  Google Scholar 

  33. Sperling RA, Parak WJ (2010) Surface modification, functionalization and bioconjugation of colloidal inorganic nanoparticles. Philos Trans Math Phys Eng Sci 368:1333–1383

    CAS  Google Scholar 

  34. Lee LC, Liong C-Y, Jemain AA (2017) A contemporary review on data preprocessing (DP) practice strategy in ATR-FTIR spectrum. Chemom Intell Lab Syst 163:64–75

    Article  CAS  Google Scholar 

  35. K.R. Beebe, R.J. Pell, M.B. Seasholtz, Chemometrics: a practical guide, Wiley New York, 1998

    Google Scholar 

  36. Donahue SM, Brown CW, Caputo B, Modell MD (1988) Near-infrared multicomponent analysis in the spectral and Fourier domains: energy content of high-pressure natural gas. Anal Chem 60:1873–1878

    Article  CAS  Google Scholar 

  37. Haaland DM, Thomas EV (1988) Partial least-squares methods for spectral analyses. 1. Relation to other quantitative calibration methods and the extraction of qualitative information. Anal Chem 60:1193–1202

    Article  CAS  Google Scholar 

  38. Kramer R (1998) Chemometric techniques for quantitative analysis. CRC Press

  39. Haaland DM, Thomas EV (2002) Partial least-squares methods for spectral analyses. 1. Relation to other quantitative calibration methods and the extraction of qualitative information. Anal Chem 60:1193–1202

    Article  Google Scholar 

  40. Abd El-Rahman M, Rezk M, Mahmoud A, Elghobashy M (2015) Design of a stable solid-contact ion-selective electrode based on polyaniline nanoparticles as ion-to-electron transducer for application in process analytical technology as a real-time analyzer. Sens Actuators B-Chem 208:14–21

    Article  Google Scholar 

  41. Yan X, Li P, Zhou B, Tang X, Li X, Weng S, Yang L, Liu J (2017) Optimal hotspots of dynamic surfaced-enhanced Raman spectroscopy for drugs quantitative detection. Anal Chem 89:4875–4881

    Article  CAS  Google Scholar 

  42. Zhao H, Hasi W, Bao L, Han S, Sha X, Sun J, Lou X, Lin D, Lv Z (2017) Rapid detection of sildenafil drugs in liquid nutraceuticals based on surface-enhanced Raman spectroscopy technology. Chin J Chem 35:1522–1528

    Article  CAS  Google Scholar 

  43. Saleh T, Al-Shalalfeh M, Al-Saadi A (2018) Silver loaded graphene as a substrate for sensing 2-thiouracil using surface-enhanced Raman scattering. Sens Actuators B-Chem 254:1110–1117

    Article  CAS  Google Scholar 

  44. Markina NE, Volkova EK, Zakharevich AM, Goryacheva IY, Markin AV (2018) SERS detection of ceftriaxone and sulfadimethoxine using copper nanoparticles temporally protected by porous calcium carbonate. Mikrochim Acta 185:481

    Article  Google Scholar 

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Authors and Affiliations

  1. Analytical Chemistry Department, Faculty of Pharmacy, October 6 University, Central axis street, 6 October City, Egypt

    Sherif M. Eid & Mohamed R. Elghobashy

  2. Analytical Chemistry Department, Faculty of Pharmacy, Cairo University, El-Kasr El-Aini Street, Cairo, ET-11562, Egypt

    Said A. Hassan, Nancy W. Nashat, Mohamed R. Elghobashy, Samah S. Abbas & Azza A. Moustafa

Authors
  1. Sherif M. Eid
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  2. Said A. Hassan
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  3. Nancy W. Nashat
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  4. Mohamed R. Elghobashy
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  5. Samah S. Abbas
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  6. Azza A. Moustafa
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Correspondence to Sherif M. Eid.

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Eid, S.M., Hassan, S.A., Nashat, N.W. et al. Optimization of localized surface plasmon resonance hot spots in surface-enhanced infrared absorption spectroscopy aluminum substrate as an optical sensor coupled to chemometric tools for the purity assay of quinary mixtures. Microchim Acta 188, 195 (2021). https://doi.org/10.1007/s00604-021-04845-7

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