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Colorimetric determination of Hg2+ based on the mercury-stimulated oxidase mimetic activity of Ag3PO4 microcubes

Microchimica Acta volume 187, Article number: 422 (2020) Cite this article

Abstract

Four kinds of Ag3PO4 materials were prepared by controlling the experimental conditions, which were developed as oxidase mimics. Experimental results showed that different synthesis methods led to distinct crystal structures, morphologies, and surface properties, which contributed to diverse oxidase-like activities of Ag3PO4 materials. Among them, Ag3PO4 microcubes (APMCs) can efficiently catalyze the oxidation of colorless 3,3′,5,5′-tetramethylbenzidine in the presence of dissolved oxygen to form a blue-colored oxide, presenting the best intrinsic oxidase mimetic ability. The higher-energy [110] facets with more oxygen vacancies exposed and more active sites coupled with more negative charge and larger specific surface area of APMCs contributed to its enhanced oxidase mimetic performance. Besides, mercury ions were proved to remarkably and selectively stimulate the oxidase-like ability of APMCs owing to the formation of Ag–Hg amalgam on its surface. Based on the stimulating effect of Hg2+ towards APMCs, a simple and rapid method for colorimetric determination of Hg2+ was thus established via the significant signal amplification and megascopic color variation. Under the optimal conditions, the sensing system showed a good linear relationship ranging from 0.1 to 7.0 μM and a detection limit of 20 nM for Hg2+, exhibiting high selectivity and good colour stability. Moreover, the colorimetric method was successfully applied to determine Hg2+ in real water samples. Considering these advantages, the developed colorimetric sensing system is expected to hold bright prospects for trace determination of Hg2+ in biological, environmental, and food samples.

The preparation process of Ag3PO4 materials and Hg2+-stimulated enhanced oxidase-like ability of Ag3PO4 microcubes in catalyzing the oxidation of TMB to generate a typical blue color, which can be applied in rapid and ultrasensitive detection of Hg2+ visually.

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Funding

This work was supported by National Natural Science Foundation of China (51702328 and 41706080), the Basic Scientific Fund for National Public Research Institutes of China (2019Y03 and 2020S02), Shandong Provincial Natural Science Foundation (ZR2017BD002), the Key Research and Development Program of Shandong Province (2018GHY115029), CAS “Light of West China” Program, Open Fund of Shandong Key Laboratory of Corrosion Science (KLCS201906), Open Fund of Laboratory for Marine Ecology and Environmental Science, Pilot National Laboratory for Marine Science and Technology (Qingdao) (LMEES201802), Open Foundation of Pilot National Laboratory for Marine Science and Technology (Qingdao) (QNLM2016ORP0410), and The Aoshan Scientific and Technological Innovation Project Financially Supported by Pilot National Laboratory for Marine Science and Technology (Qingdao) (2016ASKJ14).

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  1. Yu Zhang and Peng Ju contributed equally to this work.

Affiliations

  1. Key Laboratory of Marine Eco-Environmental Science and Technology, Marine Bioresource and Environment Research Center, First Institute of Oceanography, Ministry of Natural Resources (MNR), 6 Xianxialing Road, Qingdao, 266061, People’s Republic of China

    Yu Zhang, Peng Ju, Zhe Wang, Fenghua Jiang & Chengjun Sun

  2. Laboratory for Marine Ecology and Environmental Science, Pilot National Laboratory for Marine Science and Technology (Qingdao), 1 Wenhai Road, Qingdao, 266237, People’s Republic of China

    Peng Ju

  3. Shandong Key Laboratory of Corrosion Science, Institute of Oceanology, Chinese Academy of Sciences, 7 Nanhai Road, Qingdao, 266071, People’s Republic of China

    Peng Ju & Xiaofan Zhai

  4. School of Laboratory Medicine and Life Sciences, Wenzhou Medical University, Wenzhou, 325035, People’s Republic of China

    Liping Sun

  5. Key Laboratory of Marine Chemistry Theory and Technology, Ministry of Education, Ocean University of China, 238 Songling Road, Qingdao, 266100, People’s Republic of China

    Zhe Wang

  6. Open Studio for Marine Corrosion and Protection, Pilot National Laboratory for Marine Science and Technology (Qingdao), 1 Wenhai Road, Qingdao, 266237, People’s Republic of China

    Xiaofan Zhai

  7. Laboratory of Marine Drugs and Bioproducts, Pilot National Laboratory for Marine Science and Technology (Qingdao), 1 Wenhai Road, Qingdao, 266237, People’s Republic of China

    Chengjun Sun

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  1. Yu Zhang
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Zhang, Y., Ju, P., Sun, L. et al. Colorimetric determination of Hg2+ based on the mercury-stimulated oxidase mimetic activity of Ag3PO4 microcubes. Microchim Acta 187, 422 (2020). https://doi.org/10.1007/s00604-020-04399-0

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Keywords

  • Ag3PO4
  • Microcubes
  • Oxidase mimics
  • Colorimetric detection
  • Hg2+