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Tailoring the CeO2 morphology and its electrochemical reactivity for highly sensitive and selective determination of dopamine and epinephrine

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Abstract

Four CeO2 nanomaterials with the morphologies of a nanoplate (CeO2-p), a nanocube (CeO2-c), a porous triangular microplate (CeO2-t), and of a porous hierarchical rod-stacked nanobundle (CeO2-b) were synthesized using a hydrothermal method. They were characterized by scanning and transmission electron microscopies, X-ray diffraction and X-ray photoelectron spectroscopy. Electrochemical characterizations reveal the tuning of their morphology and the presence of exposed crystal planes of CeO2 that can be realized by changing the alkali sources. Among these materials, the CeO2-b features the largest specific surface and lowest electron transfer resistance towards the redox probe Fe(CN)63-/4-. The best voltammetric response to dopamine and epinephrine is thus achieved by using the Nafion-CeO2-b coated electrode. A sensitive and selective method was developed that can voltammetrically detect dopamine (with a peak near 0.13 V vs. SCE), and epinephrine (with a peak near 0.25 V vs. SCE). The detection limits are 2.9 and 0.67 nM, respectively.

Schematic representation of morphology tailoring of CeO2 and electrochemical sensing of dopamine and epinephrine on these CeO2 samples with different morphologies

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Acknowledgements

This work was financially supported by the National Natural Science Foundation of China (Nos. 61701352 and 21675175), the Open Foundation of Key Laboratory of Analytical Chemistry of the State Ethnic Affairs Commission (KLACOF201704) and Graduate Innovative Fund of Wuhan Institute of Technology (CX2018153 and CX2018160).

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Authors and Affiliations

  1. School of Chemistry and Environmental Engineering, Key Laboratory for Green Chemical Process of Ministry of Education, Hubei Key Lab of Novel Reactor and Green Chemical Technology, Wuhan Institute of Technology, Wuhan, 430073, China

    Chi Li, Yuanyuan Zhang, Qijin Wan & Nianjun Yang

  2. Key Laboratory of Analytical Chemistry of the State Ethnic Affairs Commission, College of Chemistry and Materials Science, South-Central University for Nationalities, Wuhan, 430074, China

    Chunya Li

  3. College of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu, 610500, China

    Qiang Ke

  4. Institute of Materials Engineering, University of Siegen, 57076, Siegen, Germany

    Nianjun Yang

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  1. Chi Li
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  2. Yuanyuan Zhang
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  3. Chunya Li
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  4. Qijin Wan
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  5. Qiang Ke
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Correspondence to Yuanyuan Zhang.

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Li, C., Zhang, Y., Li, C. et al. Tailoring the CeO2 morphology and its electrochemical reactivity for highly sensitive and selective determination of dopamine and epinephrine. Microchim Acta 187, 143 (2020). https://doi.org/10.1007/s00604-019-4100-7

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