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Electrochemical sensor based on a nanocomposite prepared from TmPO4 and graphene oxide for simultaneous voltammetric detection of ascorbic acid, dopamine and uric acid

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Abstract

A nanocomposite is described that consists of TmPO4 and graphene oxide (GO) and is used to modify a glassy carbon electrode (GCE) to obtain a sensor for simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA). GO and TmPO4 were synthesized via the Hummers method and by a hydrothermal method, respectively. The nanocomposite was characterized by transmission electron microscopy, energy dispersive X-ray spectroscopy, powder X-ray diffraction and Fourier transform infrared spectroscopy. The electrochemical properties of the modified GCE were studied by electrochemical impedance spectroscopy and cyclic voltammetry. The good performance of the modified GCE results from the synergistic effects between GO with its good electrical conductivity and of TmPO4 as the electron mediator that accelerates the electron transfer rate. Compared to a bare GCE, a GO/GCE and a TmPO4/GCE, the GO/TmPO4/GCE exhibits three well-defined and separated oxidation peaks (at −0.05, +0.13 and + 0.26 V vs. SCE). Responses to AA, DA and UA are linear in the 0.1–1.0 mM, 2–20 μM and 10–100 μM concentration ranges, respectively.

Schematic presentation of a nanocomposite that consists TmPO4 and graphene oxide (GO) and is used to modify a glassy carbon electrode (GCE) to obtain a sensor for simultaneous determination of ascorbic acid (AA), dopamine (DA) and uric acid (UA).

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Acknowledgements

This work is financially supported by the National Natural Science Foundation of China (grant No. 21465013 and 21005034), China Postdoctoral Science Foundation (grant No. 2014 M551550), Natural Science Foundation of Jiangxi Province (grant No. 20114BAB213014 and GJJ13433) and Program of Qingjiang Excellent Young Talents, Jiangxi University of Science and Technology.

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  1. School of Metallurgy and Chemical Engineering, Jiangxi University of Science and Technology, Ganzhou, 341000, China

    Haiping Huang, Yafeng Yue, Zhongzhen Chen, Yanan Chen, Shuzhen Wu, Jinsheng Liao, Suijun Liu & He-rui Wen

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  1. Haiping Huang
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  2. Yafeng Yue
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Huang, H., Yue, Y., Chen, Z. et al. Electrochemical sensor based on a nanocomposite prepared from TmPO4 and graphene oxide for simultaneous voltammetric detection of ascorbic acid, dopamine and uric acid. Microchim Acta 186, 189 (2019). https://doi.org/10.1007/s00604-019-3299-7

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