Microchimica Acta

, 185:302 | Cite as

Ionic liquid coated iron nanoparticles are promising peroxidase mimics for optical determination of H2O2

  • Faiza Zarif
  • Sajid Rauf
  • Muhammad Zahid Qureshi
  • Noor Samad Shah
  • Akhtar Hayat
  • Nawshad Muhammad
  • Abdur Rahim
  • Mian Hasnain Nawaz
  • Muhammad Nasir
Original Paper
  • 55 Downloads

Abstract

Ionic liquid coated nanoparticles (IL-NPs) consisting of zero-valent iron are shown to display intrinsic peroxidase-like activity with enhanced potential to catalyze the oxidation of the chromogenic substrate 3,3′,5,5′-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide. This results in the formation of a blue green colored product that can be detected with bare eyes and quantified by photometry at 652 nm. The IL-NPs were further doped with bismuth to enhance its catalytic properties. The Bi-doped IL-NPs were characterized by FTIR, X-ray diffraction and scanning electron microscopy. A colorimetric assay was worked out for hydrogen peroxide that is simple, sensitive and selective. Response is linear in the 30–300 μM H2O2 concentration range, and the detection limit is 0.15 μM.

Graphical abstract

Schematic of ionic liquid coated iron nanoparticles that display intrinsic peroxidase-like activity. They are capable of oxidizing the chromogenic substrate 3,3′,5,5′-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide. This catalytic oxidation generated blue-green color can be measured by colorimetry. Response is linear in the range of 30–300 μM H2O2 concentration, and the detection limit is 0.15 μM.

Keywords

Zero-valent iron particles Bismuth doping Ionic liquid coated nanoparticles TMB oxidation Stabilizing agent Peroxidase mimic Visual detection Hydrogen peroxide 

Notes

Acknowledgements

This work has been supported by IRCBM, COMSATS Institute of Information Technology Lahore, Pakistan.

Compliance with ethical standards

The author(s) declare that they have no competing interests.

Supplementary material

604_2018_2841_MOESM1_ESM.doc (942 kb)
ESM 1 (DOC 942 kb)

References

  1. 1.
    Wang N, Sun J, Chen L, Fan H, Ai S (2015) A Cu2 (OH) 3Cl-CeO2 nanocomposite with peroxidase-like activity, and its application to the determination of hydrogen peroxide, glucose and cholesterol. Microchim Acta 182:1733–1738CrossRefGoogle Scholar
  2. 2.
    Kirkman HN, Gaetani GF (2007) Mammalian catalase: a venerable enzyme with new mysteries. Trends Biochem Sci 32:44–50CrossRefGoogle Scholar
  3. 3.
    Pierre AC (2004) The sol-gel encapsulation of enzymes. Biocatalysis and Biotransformation 22:145–170CrossRefGoogle Scholar
  4. 4.
    Nossol E, Zarbin AJ (2009) A simple and innovative route to prepare a novel carbon nanotube/prussian blue electrode and its utilization as a highly sensitive H2O2 amperometric sensor. Adv Funct Mater 19:3980–3986CrossRefGoogle Scholar
  5. 5.
    Salimi A, Hallaj R, Soltanian S, Mamkhezri H (2007) Nanomolar detection of hydrogen peroxide on glassy carbon electrode modified with electrodeposited cobalt oxide nanoparticles. Anal Chim Acta 594:24–31CrossRefGoogle Scholar
  6. 6.
    Tian J, Liu Q, Asiri AM, Qusti AH, Al-Youbi AO, Sun X (2013) Ultrathin graphitic carbon nitride nanosheets: a novel peroxidase mimetic, Fe doping-mediated catalytic performance enhancement and application to rapid, highly sensitive optical detection of glucose. Nanoscale. 5:11604–11609CrossRefGoogle Scholar
  7. 7.
    Tian J, Liu Q, Ge C, Xing Z, Asiri AM, Al-Youbi AO et al (2013) Ultrathin graphitic carbon nitride nanosheets: a low-cost, green, and highly efficient electrocatalyst toward the reduction of hydrogen peroxide and its glucose biosensing application. Nanoscale. 5:8921–8924CrossRefGoogle Scholar
  8. 8.
    Wen Z, Wang Q, Li J (2008) Template synthesis of aligned carbon nanotube arrays using glucose as a carbon source: Pt decoration of inner and outer nanotube surfaces for fuel-cell catalysts. Adv Funct Mater 18:959–964CrossRefGoogle Scholar
  9. 9.
    Lee H, Habas SE, Kweskin S, Butcher D, Somorjai GA, Yang P (2006) Morphological control of catalytically active platinum nanocrystals. Angew Chem 118:7988–7992CrossRefGoogle Scholar
  10. 10.
    He Y, Niu X, Shi L, Zhao H, Li X, Zhang W, Pan J, Zhang X, Yan Y, Lan M (2017) Photometric determination of free cholesterol via cholesterol oxidase and carbon nanotube supported Prussian blue as a peroxidase mimic. Microchim Acta 184:2181–2189CrossRefGoogle Scholar
  11. 11.
    Shin HY, Kim B-G, Cho S, Lee J, Na HB, Kim MI (2017) Visual determination of hydrogen peroxide and glucose by exploiting the peroxidase-like activity of magnetic nanoparticles functionalized with a poly (ethylene glycol) derivative. Microchim Acta 184:2115–2122CrossRefGoogle Scholar
  12. 12.
    Xie F, Cao X, Qu F, Asiri AM, Sun X (2018) Cobalt nitride nanowire array as an efficient electrochemical sensor for glucose and H2O2 detection. Sensors Actuators B Chem 255:1254–1261CrossRefGoogle Scholar
  13. 13.
    Rogers RD, Seddon KR (2003) Ionic liquids--solvents of the future? Science 302:792–793CrossRefGoogle Scholar
  14. 14.
    Wang X, Hao J (2016) Recent advances in ionic liquid-based electrochemical biosensors. Sci Bull 61:1281–1295CrossRefGoogle Scholar
  15. 15.
    Nakashima K, Wada M, Kuroda N, Akiyama S, Imai K (1994) High-performance liquid chromatographic determination of hydrogen peroxide with peroxyoxalate chemiluminescence detection. J Liq Chromatogr Relat Technol 17:2111–2126CrossRefGoogle Scholar
  16. 16.
    Choleva TG, Gatselou VA, Tsogas GZ, Giokas DL (2018) Intrinsic peroxidase-like activity of rhodium nanoparticles, and their application to the colorimetric determination of hydrogen peroxide and glucose. Microchim Acta 185:22CrossRefGoogle Scholar
  17. 17.
    Huang L, Zhu W, Zhang W, Chen K, Wang J, Wang R, Yang Q, Hu N, Suo Y, Wang J (2018) Layered vanadium (IV) disulfide nanosheets as a peroxidase-like nanozyme for colorimetric detection of glucose. Microchim Acta 185:7CrossRefGoogle Scholar
  18. 18.
    Lin T, Zhong L, Chen H, Li Z, Song Z, Guo L, Fu F (2017) A sensitive colorimetric assay for cholesterol based on the peroxidase-like activity of MoS 2 nanosheets. Microchim Acta 184:1233–1237CrossRefGoogle Scholar
  19. 19.
    Lu Y, Yu J, Ye W, Yao X, Zhou P, Zhang H, Zhao S, Jia L (2016) Spectrophotometric determination of mercury (II) ions based on their stimulation effect on the peroxidase-like activity of molybdenum disulfide nanosheets. Microchim Acta 183:2481–2489CrossRefGoogle Scholar
  20. 20.
    Chaudhari RD, Joshi AB, Srivastava R (2012) Uric acid biosensor based on chemiluminescence detection using a nano-micro hybrid matrix. Sensors Actuators B Chem 173:882–889CrossRefGoogle Scholar
  21. 21.
    Chen X, Wu G, Cai Z, Oyama M, Chen X (2014) Advances in enzyme-free electrochemical sensors for hydrogen peroxide, glucose, and uric acid. Microchim Acta 181:689–705CrossRefGoogle Scholar
  22. 22.
    Xiong X, You C, Cao X, Pang L, Kong R, Sun X (2017) Ni2P nanosheets array as a novel electrochemical catalyst electrode for non-enzymatic H2O2 sensing. Electrochim Acta 253:517–521CrossRefGoogle Scholar
  23. 23.
    Wang Z, Xie F, Liu Z, Du G, Asiri AM, Sun X (2017) High-performance non-enzyme hydrogen peroxide detection in neutral solution: using a nickel borate Nanoarray as a 3D electrochemical sensor. Chem Eur J 23:16179–16183CrossRefGoogle Scholar
  24. 24.
    Wang B, Ju P, Zhang D, Han X, Zheng L, Yin X, Sun C (2016) Colorimetric detection of H2O2 using flower-like Fe2 (MoO4) 3 microparticles as a peroxidase mimic. Microchim Acta 183:3025–3033CrossRefGoogle Scholar
  25. 25.
    Chen J, Chen Q, Chen J, Qiu H (2016) Magnetic carbon nitride nanocomposites as enhanced peroxidase mimetics for use in colorimetric bioassays, and their application to the determination of H 2 O 2 and glucose. Microchim Acta 183:3191–3199CrossRefGoogle Scholar
  26. 26.
    Liu S, Tian J, Wang L, Luo Y, Sun X (2012) A general strategy for the production of photoluminescent carbon nitride dots from organic amines and their application as novel peroxidase-like catalysts for colorimetric detection of H 2 O 2 and glucose. RSC Adv 2:411–413CrossRefGoogle Scholar
  27. 27.
    Chen X, Ji D, Wang X, Zang L. Review on Nano zerovalent Iron (nZVI): From Modification to Environmental Applications. IOP Conference Series: Earth and Environmental Science: IOP Publishing; 2017. p. 012004Google Scholar
  28. 28.
    Qian W, Xu Y, Zhu H, Yu C (2012) Properties of pure 1-methylimidazolium acetate ionic liquid and its binary mixtures with alcohols. J Chem Thermodyn 49:87–94CrossRefGoogle Scholar
  29. 29.
    Fang Z, Chen J, Qiu X, Qiu X, Cheng W, Zhu L (2011) Effective removal of antibiotic metronidazole from water by nanoscale zero-valent iron particles. Desalination 268:60–67CrossRefGoogle Scholar
  30. 30.
    Lin K, Ding J, Huang X (2012) Debromination of tetrabromobisphenol a by nanoscale zerovalent iron: kinetics, influencing factors, and pathways. Ind Eng Chem Res 51:8378–8385CrossRefGoogle Scholar
  31. 31.
    Zhang X-Y, Li H-P, Cui X-L, Lin Y (2010) Graphene/TiO 2 nanocomposites: synthesis, characterization and application in hydrogen evolution from water photocatalytic splitting. J Mater Chem 20:2801–2806CrossRefGoogle Scholar
  32. 32.
    Feng J, Lim T-T (2007) Iron-mediated reduction rates and pathways of halogenated methanes with nanoscale Pd/Fe: analysis of linear free energy relationship. Chemosphere 66:1765–1774CrossRefGoogle Scholar
  33. 33.
    Nasir M, Rauf S, Muhammad N, Nawaz MH, Chaudhry AA, Malik MH et al (2017) Biomimetic nitrogen doped titania nanoparticles as a colorimetric platform for hydrogen peroxide detection. J Colloid Interface Sci 505:1147–1157CrossRefGoogle Scholar
  34. 34.
    Lu J, Xiong Y, Liao C, Ye F (2015) Colorimetric detection of uric acid in human urine and serum based on peroxidase mimetic activity of MIL-53 (Fe). Anal Methods 7:9894–9899CrossRefGoogle Scholar
  35. 35.
    Wu H, Yin J-J, Wamer WG, Zeng M, Lo YM (2014) Reactive oxygen species-related activities of nano-iron metal and nano-iron oxides. J Food Drug Anal 22:86–94CrossRefGoogle Scholar
  36. 36.
    De A, De AK, Panda GS, Haldar S (2016) Synthesis of iron-based nanoparticles and comparison of their catalytic activity for degradation of phenolic waste water in a small-scale batch reactor. Desalin Water Treat 57:25170–25180CrossRefGoogle Scholar
  37. 37.
    Gao L, Zhuang J, Nie L, Zhang J, Zhang Y, Gu N, Wang T, Feng J, Yang D, Perrett S, Yan X (2007) Intrinsic peroxidase-like activity of ferromagnetic nanoparticles. Nat Nanotechnol 2:577–583CrossRefGoogle Scholar
  38. 38.
    Gao L, Fan K, Yan X (2017) Iron oxide Nanozyme: a multifunctional enzyme mimetic for biomedical applications. Theranostics 7:3207–3227CrossRefGoogle Scholar
  39. 39.
    Lee C, Sedlak DL (2008) Enhanced formation of oxidants from bimetallic nickel−Iron nanoparticles in the presence of oxygen. Environ Sci Technol 42:8528–8533CrossRefGoogle Scholar
  40. 40.
    Menhaj AB, Smith BD, Liu J (2012) Exploring the thermal stability of DNA-linked gold nanoparticles in ionic liquids and molecular solvents. Chem Sci 3:3216–3220CrossRefGoogle Scholar
  41. 41.
    Qiao F, Chen L, Li X, Li L, Ai S (2014) Peroxidase-like activity of manganese selenide nanoparticles and its analytical application for visual detection of hydrogen peroxide and glucose. Sensors Actuators B Chem 193:255–262CrossRefGoogle Scholar
  42. 42.
    Choleva TG, Gatselou VA, Tsogas GZ, Giokas DL (2017) Intrinsic peroxidase-like activity of rhodium nanoparticles, and their application to the colorimetric determination of hydrogen peroxide and glucose. Microchim Acta 185:22CrossRefGoogle Scholar
  43. 43.
    Huang L, Zhu W, Zhang W, Chen K, Wang J, Wang R et al (2017) Layered vanadium(IV) disulfide nanosheets as a peroxidase-like nanozyme for colorimetric detection of glucose. Microchim Acta 185:7CrossRefGoogle Scholar
  44. 44.
    Nguyen ND, Nguyen TV, Chu AD, Tran HV, Tran LT, Huynh CD (2018) A label-free colorimetric sensor based on silver nanoparticles directed to hydrogen peroxide and glucose. Arab J ChemGoogle Scholar
  45. 45.
    Dai D, Liu H, Ma H, Huang Z, Gu C, Zhang M (2018) In-situ synthesis of Cu2OAu nanocomposites as nanozyme for colorimetric determination of hydrogen peroxide. J Alloys Compd 747:676–683CrossRefGoogle Scholar
  46. 46.
    Ding C, Yan Y, Xiang D, Zhang C, Xian Y (2016) Magnetic Fe3S4 nanoparticles with peroxidase-like activity, and their use in a photometric enzymatic glucose assay. Microchim Acta 183:625–631CrossRefGoogle Scholar
  47. 47.
    Zhong Y, Deng C, He Y, Ge Y, Song G (2016) Exploring a monothiolated β-cyclodextrin as the template to synthesize copper nanoclusters with exceptionally increased peroxidase-like activity. Microchim Acta 183:2823–2830CrossRefGoogle Scholar
  48. 48.
    Xiang Z, Wang Y, Ju P, Zhang D (2016) Optical determination of hydrogen peroxide by exploiting the peroxidase-like activity of AgVO3 nanobelts. Microchim Acta 183:457–463CrossRefGoogle Scholar
  49. 49.
    Basiri S, Mehdinia A, Jabbari A (2018) A sensitive triple colorimetric sensor based on plasmonic response quenching of green synthesized silver nanoparticles for determination of Fe2+, hydrogen peroxide, and glucose. Colloids Surf A Physicochem Eng Asp 545:138–146CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  • Faiza Zarif
    • 1
  • Sajid Rauf
    • 2
  • Muhammad Zahid Qureshi
    • 1
  • Noor Samad Shah
    • 3
  • Akhtar Hayat
    • 2
  • Nawshad Muhammad
    • 2
  • Abdur Rahim
    • 2
  • Mian Hasnain Nawaz
    • 2
  • Muhammad Nasir
    • 2
  1. 1.Department of ChemistryGovernment College UniversityLahorePakistan
  2. 2.Interdisciplinary Research Centre in Biomedical Materials (IRCBM) COMSATS Institute of Information TechnologyLahorePakistan
  3. 3.Department of Environmental SciencesCOMSATS Institute of Information TechnologyVehariPakistan

Personalised recommendations