Skip to main content
Log in

Screen-printed electrode modified with a composite prepared from graphene oxide nanosheets and Mn3O4 microcubes for ultrasensitive determination of nitrite

  • Original Paper
  • Published:
Microchimica Acta Aims and scope Submit manuscript

Abstract

The authors describe a screen-printed electrode (SPE) modified with a composite consisting of Mn3O4 microcubes and thin sheets of graphene oxide for use in amperometric determination of nitrite. The composite was prepared by a hydrothermal method, and its morphology, elemental composition, diffraction, impedance and electrochemical properties were studied. The modified SPE displays excellent electrocatalytic activity towards nitrite, and the oxidation peak current (measured typically at 0.70 V vs. Ag/AgCl) is related to the concentration of nitrite in the range between 0.1 and 1300 μM, with a 20 nM detection limit. The method was successfully applied to the determination of nitrite in spiked samples of beef and water.

Electrochemical determination of nitrite using graphene oxide nanosheets/Mn3O4 microcubes composite modified screen-printed electrode

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. Allen JD, Gow AJ (2009) Nitrite, NO and hypoxic vasodilation. Br J Pharmacol 158(7):1653–1654

    Article  CAS  Google Scholar 

  2. Bryan NS, Fernandez BO, Bauer SM, Garcia-Saura MF, Milsom AB, Rassaf T, Maloney RE, Bharti A, Rodriguez J, Feelisch M (2005) Nitrite is a signaling molecule and regulator of gene expression in mammalian tissues. Nat Chem Biol 1(5):290–297

    Article  CAS  Google Scholar 

  3. Silva MM, Lidon FC (2016) Food preservatives-an overview on applications and side effects. Emirates J Food Agri 28(6):366

    Article  Google Scholar 

  4. Liu P, Zhang X, Feng L, Xiong H, Wang S (2011) Direct electrochemistry of hemoglobin on graphene nanosheet-based modified electrode and its electrocatalysis to nitrite. Am J Biomed Sci 3(1):69–76

    Google Scholar 

  5. Humans IWGotEoCRt (2010) IARC monographs on the evaluation of carcinogenic risks to humans. Ingested nitrate and nitrite, and cyanobacterial peptide toxins. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans 94:v

  6. Yue R, Lu Q, Zhou Y (2011) A novel nitrite biosensor based on single-layer graphene nanoplatelet–protein composite film. Biosens Bioelectron 26(11):4436–4441

    Article  CAS  Google Scholar 

  7. Council NR (1995) Nitrate and nitrite in drinking water. National Academies Press,

  8. Mani V, Periasamy AP, Chen S-M (2012) Highly selective amperometric nitrite sensor based on chemically reduced graphene oxide modified electrode. Electrochem Commun 17:75–78

    Article  CAS  Google Scholar 

  9. Geim AK, Grigorieva IV (2013) Van der Waals heterostructures. Nature 499(7459):419–425

    Article  CAS  Google Scholar 

  10. Govindasamy M, Mani V, Chen S-M, Karthik R, Manibalan K, Umamaheswari R (2016) MoS2 flowers grown on graphene/carbon nanotubes: a versatile substrate for electrochemical determination of hydrogen peroxide. Int J Electrochem Sci 11:2954–2961

    Article  CAS  Google Scholar 

  11. Gangaraju D, Sridhar V, Lee I, Park H (2016) Graphene–carbon nanotube–Mn 3 O 4 mesoporous nano-alloys as high capacity anodes for lithium-ion batteries. J Alloys Compounds 699:106–111

  12. Ejigu A, Edwards M, Walsh DA (2015) Synergistic catalyst–support interactions in a graphene–Mn3O4 Electrocatalyst for vanadium redox flow batteries. ACS Catal 5(12):7122–7130. doi:10.1021/acscatal.5b01973

    Article  CAS  Google Scholar 

  13. Li Y, Ni X (2017) The enhanced Supercapacitive performance of the hybrid material integrating doped-polymer with the composite of graphene oxide and Mn 3 O 4. Electrochimica Acta 227:162–169

  14. Yuan Z, Chen S, Liu B (2017) Nitrogen-doped reduced graphene oxide-supported Mn3O4: an efficient heterogeneous catalyst for the oxidation of vanillyl alcohol to vanillin. J Mater Sci 52(1):164–172

    Article  CAS  Google Scholar 

  15. Sayle TX, Caddeo F, Zhang X, Sakthivel T, Das S, Seal S, Ptasinska S, Sayle DC (2016) Structure–activity map of ceria nanoparticles, Nanocubes, and mesoporous architectures. Chem Mater 28(20):7287–7295

    Article  CAS  Google Scholar 

  16. Barton J, García MBG, Santos DH, Fanjul-Bolado P, Ribotti A, McCaul M, Diamond D, Magni P (2016) Screen-printed electrodes for environmental monitoring of heavy metal ions: a review. Microchim Acta 183(2):503–517

    Article  CAS  Google Scholar 

  17. Marcano DC, Kosynkin DV, Berlin JM, Sinitskii A, Sun Z, Slesarev A, Alemany LB, Lu W, Tour JM (2010) Improved synthesis of graphene oxide. ACS Nano 4(8):4806–4814

    Article  CAS  Google Scholar 

  18. Özkaya T, Baykal A, Toprak MS (2008) 2-pyrrolidone-capped Mn3O4 nanocrystals. Cent Eur J Chem 6(3):465

    Google Scholar 

  19. Wang D, Li Y, Wang Q, Wang T (2012) Facile synthesis of porous Mn3O4 nanocrystal–graphene nanocomposites for electrochemical supercapacitors. Eur J Inorg Chem 2012(4):628–635

    Article  CAS  Google Scholar 

  20. Mani V, Huang S-T, Devasenathipathy R, Yang TC (2016) Electropolymerization of cobalt tetraamino-phthalocyanine at reduced graphene oxide for electrochemical determination of cysteine and hydrazine. RSC Adv 6(44):38463–38469

    Article  CAS  Google Scholar 

  21. Mani V, Dinesh B, Chen S-M, Saraswathi R (2014) Direct electrochemistry of myoglobin at reduced graphene oxide-multiwalled carbon nanotubes-platinum nanoparticles nanocomposite and biosensing towards hydrogen peroxide and nitrite. Biosens Bioelectron 53:420–427

    Article  CAS  Google Scholar 

  22. Si P, Dong X-C, Chen P, Kim D-H (2013) A hierarchically structured composite of Mn 3 O 4/3D graphene foam for flexible nonenzymatic biosensors. J Mater Chem B 1(1):110–115

    Article  CAS  Google Scholar 

  23. Liu C, Zhang H, Tang Y, Luo S (2014) Controllable growth of graphene/cu composite and its nanoarchitecture-dependent electrocatalytic activity to hydrazine oxidation. J Mater Chem A 2(13):4580–4587

    Article  CAS  Google Scholar 

  24. Zhang S, Liu X, Huang N, Lu Q, Liu M, Li H, Zhang Y, Yao S (2016) Sensitive detection of hydrogen peroxide and nitrite based on silver/carbon nanocomposite synthesized by carbon dots as reductant via one step method. Electrochim Acta 211:36–43

    Article  CAS  Google Scholar 

  25. Lin P, Chai F, Zhang R, Xu G, Fan X, Luo X (2016) Electrochemical synthesis of poly (3, 4-ethylenedioxythiophene) doped with gold nanoparticles, and its application to nitrite sensing. Microchim Acta 183(3):1235–1241

    Article  CAS  Google Scholar 

  26. Chen D, Jiang J, Du X (2016) Electrocatalytic oxidation of nitrite using metal-free nitrogen-doped reduced graphene oxide nanosheets for sensitive detection. Talanta 155:329–335

    Article  CAS  Google Scholar 

  27. Mehmeti E, Stanković DM, Hajrizi A, Kalcher K (2016) The use of graphene nanoribbons as efficient electrochemical sensing material for nitrite determination. Talanta 159:34–39

  28. Li Z, An Z, Guo Y, Zhang K, Chen X, Zhang D, Xue Z, Zhou X, Lu X (2016) Au-Pt bimetallic nanoparticles supported on functionalized nitrogen-doped graphene for sensitive detection of nitrite. Talanta 161:713–720

    Article  CAS  Google Scholar 

  29. Shen Y, Rao D, Bai W, Sheng Q, Zheng J (2017) Preparation of high-quality palladium nanocubes heavily deposited on nitrogen-doped graphene nanocomposites and their application for enhanced electrochemical sensing. Talanta 165:304–312

    Article  CAS  Google Scholar 

  30. Chen L, Liu X, Wang C, Lv S, Chen C (2017) Amperometric nitrite sensor based on a glassy carbon electrode modified with electrodeposited poly (3, 4-ethylenedioxythiophene) doped with a polyacenic semiconductor. Microchimica Acta 184(7):2073–2079

  31. Wang G, Han R, Feng X, Li Y, Lin J, Luo X (2017) A glassy carbon electrode modified with poly (3, 4-ethylenedioxythiophene) doped with nano-sized hydroxyapatite for amperometric determination of nitrite. Microchim Acta 184(6):1721–1727

    Article  CAS  Google Scholar 

  32. Li S-J, Zhao G-Y, Zhang R-X, Hou Y-L, Liu L, Pang H (2013) A sensitive and selective nitrite sensor based on a glassy carbon electrode modified with gold nanoparticles and sulfonated graphene. Microchim Acta 180(9–10):821–827

    Article  CAS  Google Scholar 

  33. Meng Z, Liu B, Zheng J, Sheng Q, Zhang H (2011) Electrodeposition of cobalt oxide nanoparticles on carbon nanotubes, and their electrocatalytic properties for nitrite electrooxidation. Microchim Acta 175(3–4):251–257

    Article  CAS  Google Scholar 

  34. Haldorai Y, Kim JY, Vilian ATE, Heo NS, Huh YS, Han Y-K (2016) An enzyme-free electrochemical sensor based on reduced graphene oxide/Co3O4 nanospindle composite for sensitive detection of nitrite. Sensors Actuators B Chem 227:92–99. doi:10.1016/j.snb.2015.12.032

    Article  CAS  Google Scholar 

  35. Radhakrishnan S, Krishnamoorthy K, Sekar C, Wilson J, Kim SJ (2014) A highly sensitive electrochemical sensor for nitrite detection based on Fe 2 O 3 nanoparticles decorated reduced graphene oxide nanosheets. Appl Catal B Environ 148:22–28

    Article  Google Scholar 

  36. Pandikumar A, Yusoff N, Huang NM, Lim HN (2015) Electrochemical sensing of nitrite using a glassy carbon electrode modified with reduced functionalized graphene oxide decorated with flower-like zinc oxide. Microchim Acta 182(5–6):1113–1122

    Google Scholar 

  37. Wang Q, Yun Y (2012) A nanomaterial composed of cobalt nanoparticles, poly (3, 4-ethylenedioxythiophene) and graphene with high electrocatalytic activity for nitrite oxidation. Microchim Acta 177(3–4):411–418

    Article  CAS  Google Scholar 

  38. Huang S-S, Liu L, Mei L-P, Zhou J-Y, Guo F-Y, Wang A-J, Feng J-J (2016) Electrochemical sensor for nitrite using a glassy carbon electrode modified with gold-copper nanochain networks. Microchim Acta 183(2):791–797

    Article  CAS  Google Scholar 

  39. Wang H, Wen F, Chen Y, Sun T, Meng Y, Zhang Y (2016) Electrocatalytic determination of nitrite based on straw cellulose/molybdenum sulfide nanocomposite. Biosens Bioelectron 85:692–697

    Article  CAS  Google Scholar 

  40. Rabti A, Aoun SB, Raouafi N (2016) A sensitive nitrite sensor using an electrode consisting of reduced graphene oxide functionalized with ferrocene. Microchim Acta 183(12):3111–3117

    Article  CAS  Google Scholar 

  41. Wu W, Li Y, Jin J, Wu H, Wang S, Ding Y, Ou J (2016) Sensing nitrite with a glassy carbon electrode modified with a three-dimensional network consisting of Ni7S6 and multi-walled carbon nanotubes. Microchim Acta 183(12):3159–3166

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by the National Science Council and the Ministry of Education of Taiwan (Republic of China) and National Taipei University of Technology, Taipei, Taiwan.

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Shen-Ming Chen or Veerappan Mani.

Ethics declarations

The author(s) declare that they have no competing interests.

Electronic supplementary material

ESM 1

(DOCX 3.40 mb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Muthumariappan, A., Govindasamy, M., Chen, SM. et al. Screen-printed electrode modified with a composite prepared from graphene oxide nanosheets and Mn3O4 microcubes for ultrasensitive determination of nitrite. Microchim Acta 184, 3625–3634 (2017). https://doi.org/10.1007/s00604-017-2379-9

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00604-017-2379-9

Keywords

Navigation