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A glassy carbon electrode modified with poly(3,4-ethylenedioxythiophene) doped with nano-sized hydroxyapatite for amperometric determination of nitrite

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Abstract

A conducting polymer composite was prepared from nano-sized hydroxyaptite (nHAp) doped into poly(3,4-ethylenedioxythiophene) (PEDOT) and then electrodeposited on a glassy carbon electrode (GCE). The nHAp carries carboxy groups and therefore is negatively charged at moderate pH value. When doped into PEDOT (PEDOT-nHAp), it forms a uniform and stable film that exhibits low electrochemical impedance, a large specific surface, and high activity toward the electrochemical oxidation of nitrite. Under optimized conditions and at a relatively low working potential of 0.78 V (vs. SCE), the modified GCE exhibited a linear amperometric response in the 0.25 μM to 1.05 mM nitrite concentration range, and the limit of detection is as low as 83 nM.

A highly sensitive nitrite sensor was developed based on conducting polymer poly(3,4-ethylenedioxythiophene) (PEDOT) doped with carboxyl group functionalized hydroxyapatite nanoparticles, which exhibited a large surface area and good conductivity and stability.

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Acknowledgements

This research was supported by the National Natural Science Foundation of China (21422504 and 21275087), the Natural Science Foundation of Shandong Province of China (JQ201406), the Taishan Scholar Program of Shandong Province of China and the Domestic Visiting Scholar Program of Shandong Province of China for Young Backbone Teachers of Colleges and Universities.

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Authors and Affiliations

  1. Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao, 266042, China

    Guixiang Wang, Rui Han, Xiuying Feng, Yinan Li, Jiehua Lin & Xiliang Luo

  2. College of Chemistry and Chemical Engineering, Taishan University, Taian, 271021, People’s Republic of China

    Guixiang Wang

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  1. Guixiang Wang
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  2. Rui Han
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  3. Xiuying Feng
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  4. Yinan Li
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Correspondence to Xiliang Luo.

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Wang, G., Han, R., Feng, X. et al. A glassy carbon electrode modified with poly(3,4-ethylenedioxythiophene) doped with nano-sized hydroxyapatite for amperometric determination of nitrite. Microchim Acta 184, 1721–1727 (2017). https://doi.org/10.1007/s00604-017-2180-9

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