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Synergetic dual recognition and separation of the fungicide carbendazim by using magnetic nanoparticles carrying a molecularly imprinted polymer and immobilized β-cyclodextrin

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Abstract

The authors describe a nanomaterial for solid-phase extraction of carbendazim. Magnetic molecularly imprinted polymer nanoparticles (mag-MIP-NPs) were obtained by immobilizing the MIP and a thiolated β-cyclodextrin on the surface of magnetite (Fe3O4) nanoparticles coated with gold nanoparticles. Both the recognition sites of the MIP and the hydrophobic cavities in the β-cyclodextrin contribute to the specific molecular recognition and extraction of carbendazim. The mag-MIP-NPs have an apparent adsorption capacity of 190 mg⋅g‾1. Spiked vegetables were analyzed by using this material for extraction of carbendazim prior to its determination by ultra performance liquid chromatography (UHPLC). Recoveries range from 90.5 % to 109 %, and the detection limit is 3.0 pg⋅mL‾1.

Magnetic molecularly imprinted polymer nanoparticles (mag-MIP-NPs) were synthesized based on a thiolated β-cyclodextrin on the magnetic nanocomposite. Due to the synergetic dual recognition and separation effect, mag-MIP-NPs showed the good adsorption capacity of 190 mg⋅g‾1 for carbendazim.

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Acknowledgments

Project supported by the Natural Science Foundation of Hainan Province of China (No. 20152024) and the Fundamental Scientific Research Funds for Chinese Academy of Tropical Agricultural Sciences (No. 1630042015009).

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Authors and Affiliations

  1. Analysis and Test Center of Chinese Academy of Tropical Agricultural Sciences, Haikou, 571101, China

    Shuhuai Li, Xuejin Wu, Qun Zhang & Pingping Li

  2. Hainan Provincial Key Laboratory of Quality and Safety for Tropical Fruits and Vegetables, Haikou, 571101, China

    Shuhuai Li, Xuejin Wu, Qun Zhang & Pingping Li

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  1. Shuhuai Li
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  2. Xuejin Wu
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  4. Pingping Li
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Correspondence to Shuhuai Li.

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Li, S., Wu, X., Zhang, Q. et al. Synergetic dual recognition and separation of the fungicide carbendazim by using magnetic nanoparticles carrying a molecularly imprinted polymer and immobilized β-cyclodextrin. Microchim Acta 183, 1433–1439 (2016). https://doi.org/10.1007/s00604-016-1765-z

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  • DOI: https://doi.org/10.1007/s00604-016-1765-z

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