Microchimica Acta

, Volume 183, Issue 2, pp 697–707

SERS based point-of-care detection of food-borne pathogens

  • Nawfal Adam Mungroo
  • Gustavo Oliveira
  • Suresh Neethirajan
Original Paper

DOI: 10.1007/s00604-015-1698-y

Cite this article as:
Mungroo, N.A., Oliveira, G. & Neethirajan, S. Microchim Acta (2016) 183: 697. doi:10.1007/s00604-015-1698-y


The authors have developed a microfluidic platform for improved detection of pathogenic bacteria by using silver nanoparticles and new platforms for chemometric data analysis, viz. a combination of principle component analysis and linear discriminant analysis. The method can distinguish eight key foodborne pathogens (E. coli, S. typhimirium, S. enteritis, Pseudomonas aeruginosa, L. monocytogenes, L. innocua, MRSA 35 and MRSA 86) and, hence, holds good promise for use in the food industry.

Graphical Abstract

A microfluidic and surface-enhanced Raman scattering substrate integrated biosensing platform involving silver nanoparticles is demonstrated for rapid and on-site detection and discrimination of polymicrobial food-borne pathogenic bacteria.


Microfluidics Food safety Food analysis Principle component analysis Linear discriminant analysis Silver nanoparticles Raman spectroscopy 

Funding information

Funder NameGrant NumberFunding Note
Natural Sciences and Engineering Research Council of Canada
  • 400929
Mitacs Globalink
    Ontario Ministry of Research and Innovation
    • 520512

    Copyright information

    © Springer-Verlag Wien 2015

    Authors and Affiliations

    • Nawfal Adam Mungroo
      • 1
    • Gustavo Oliveira
      • 1
    • Suresh Neethirajan
      • 1
    1. 1.Bionano Laboratory, School of EngineeringUniversity of GuelphGuelphCanada

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