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Synthesis and analytical applications of molecularly imprinted polymers on the surface of carbon nanotubes: a review


This review (with 142 references) summarize the state of the art in molecularly imprinting technology as applied to the surface of carbon nanotubes (CNTs) which result in so-called CNTs@MIPs. These nanomaterials offer a remedy to the flaws of traditional MIPs, such as poor site accessibility for templates, slow mass transfer and template leakage. They also are flexible in that different materials can be integrated with CNTs. Given the advantages of using CNT@MIPs, this technology has experienced rapid expansion, not the least because CNT@MIPs can be produced at low cost and by a variety of synthetic approaches. We summarize methods of, and recent advances in the synthesis of CNT@MIPs, and then highlight some representative applications. We also comment on their potential future developments and research directions.

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2 or 4-VP:

2-or 4-vinylpyridine


Acrylic acid


(p-acryloylaminophenyl)-{(4-aminophenyl)-diethyl ammonium}-ethylphosphate




Ammonium persulfate








Bovine serum albumin


Controlled/living free radical polymerization


Carbon nanotubes


Molecularly imprinted polymers on the surface of carbon nanotubes




Chitosan derivative


Dimethyl acetamide


Dimethyl formamide


Dimethyl sulfoxide








Ethylene glycol dimethacrylate






Methacrylic acid


Molecularly imprinted membrane


Molecular imprinted polypyrrole


Molecularly imprinted polymers


Molecular imprinting technology




Multiwalled carbon nanotubes




4-nitrophenyl acrylate


Ochratoxin A


Polyamide amine


Polyethylene glycol


Pentaerythritol triacrylate






Solid-phase extraction


Solid phase micro extraction


Single-walled carbon nanotubes








Micro-solid phase preconcentration


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This work was supported by the National Natural Science Foundation of China(Grant NO. 81402899), the Open Project of Key Laboratory of Modern Toxicology of the Ministry of Education (Grant NO. NMUMT201404), and the Project Funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions.

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Correspondence to Hua He.

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Hao Dai and Deli Xiao equally contributed to this work and should be considered co-first authors.

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Dai, H., Xiao, D., He, H. et al. Synthesis and analytical applications of molecularly imprinted polymers on the surface of carbon nanotubes: a review. Microchim Acta 182, 893–908 (2015).

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  • Multi-walled carbon nanotubes
  • Molecularly imprinted polymers
  • Synthesis
  • Nanoparticles
  • Solid-phase extraction
  • Chemical sensor