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Amperometric sensor for ascorbic acid based on a glassy carbon electrode modified with gold-silver bimetallic nanotubes in a chitosan matrix

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Abstract

We report on an amperometric sensor for ascorbic acid (AA) that is based on highly dense gold-silver nanotubes in a chitosan film on a glassy carbon electrode. The nanotubes were synthesized by a poly(vinyl pyrrolidone)-mediated polyol method employing a replacement reaction with silver nanowires as templates, and were characterized by scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray diffraction. Under the optimal conditions, the sensor exhibits good electrocatalytic activity towards the oxidation of AA, and this enables the determination of AA in the 5 μM to 2 mM concentration range, with a detection limit at 2 μM (at an S/N of 3). The response time is 2 s. The sensor displays good reproducibility, selectivity, sensitivity, and long-term stability.

In this paper, an amperometric electrochemical sensor for detection of ascorbic acid was fabricated based on highly dense gold-silver nanotubes and chitosan film. The biosensor showed good reproducibility, anti-interferant ability, high sensitivity, low detection limit, fast response, and long-term stability.

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Acknowledgments

This research was supported by the National Natural Science Foundation of China (No. 30800247, 20805043).

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Authors and Affiliations

  1. Department of Chemistry, Zhejiang University, Hangzhou, 310027, People’s Republic of China

    Penghao Yang, Xia Gao, Lisha Wang, Qi Wu, Zhichun Chen & Xianfu Lin

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  1. Penghao Yang
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  2. Xia Gao
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  3. Lisha Wang
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  4. Qi Wu
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  5. Zhichun Chen
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  6. Xianfu Lin
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Correspondence to Qi Wu or Xianfu Lin.

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Yang, P., Gao, X., Wang, L. et al. Amperometric sensor for ascorbic acid based on a glassy carbon electrode modified with gold-silver bimetallic nanotubes in a chitosan matrix. Microchim Acta 181, 231–238 (2014). https://doi.org/10.1007/s00604-013-1104-6

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  • DOI: https://doi.org/10.1007/s00604-013-1104-6

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