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Modelling the size and polydispersity of magnetic hybrid nanoparticles for luminescent sensing of oxygen

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Abstract

We report on a strategy to model both the size (d) and the polydispersity (PdI) of magnetic oxygen-sensitive nanoparticles with a typical size of 200 nm in order to increase the surface area. The strategy is based on experimental design and Response Surface Methodology. Nanoparticles were prepared by miniemulsion solvent evaporation of solutions of poly(styrene-co-maleic anhydride). Features of this strategy include (1) a quick selection of the most important variables that govern d and PdI; (2) a better understanding of the parameters that affect the performance of the polymer; and (3) optimized conditions for the synthesis of nanoparticles of targeted d and PdI. The results were used to produce nanoparticles in sizes that range from 100 to 300 nm and with small polydispersity. The addition of a platinum porphyrin complex that acts as a luminescent probe for oxygen and of magnetite (Fe3O4) to the polymeric particles, did not affect d and PdI, thus demonstrating that this strategy simplifies their synthesis. The resulting luminescent and magnetic sensor nanoparticles respond to dissolved oxygen with sensitivity (Stern-Volmer constant) of around 35 bar−1.

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Acknowledgments

The authors gratefully acknowledge the financial support of the Junta de Andalucía (Excellence Project P07-FQM-2625, P07-FQM-2738 and Marín-Suárez’s grant) and the Spanish Ministry of Economy and Competitiveness CTQ2011-25316. The authors are also grateful to Santiago Medina-Rodriguez for his advice using MATLAB.

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Authors and Affiliations

  1. Department of Analytical Chemistry, University of Granada, Avda. Fuentenueva s/n, 18071, Granada, Spain

    Marta Marín-Suárez, María C. Arias-Martos, Jorge F. Fernández-Sánchez & Alberto Fernández-Gutiérrez

  2. Department of Analytical Chemistry, University of Extremadura, Avda. de Elvas s/n, 06071, Badajoz, Spain

    Teresa Galeano-Díaz

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  1. Marta Marín-Suárez
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  2. María C. Arias-Martos
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Correspondence to Marta Marín-Suárez.

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Marín-Suárez, M., Arias-Martos, M.C., Galeano-Díaz, T. et al. Modelling the size and polydispersity of magnetic hybrid nanoparticles for luminescent sensing of oxygen. Microchim Acta 180, 1201–1209 (2013). https://doi.org/10.1007/s00604-013-1054-z

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