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Electrochemical sensing of hydrogen peroxide using metal nanoparticles: a review

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Abstract

We are reviewing the state of electrochemical sensing of H2O2 based on the use of metal nanoparticles. The article is divided into subsections on sensors based on nanoparticles made from Ag, Pt, Pd, Cu, bimetallic nanoparticles and other metals. Some sensors display high sensitivity, fast response, and good stability. The review is subdivided into sections on sensors based on heme proteins and on nonenzymatic sensors. We also discussed the challenges of nanoscaled sensors and their future aspects.

Sensing mechanism of (A) mediator-based enzyme biosensor, (B) mediator-less enzyme biosensor and (C) nonenzymatic sensors with metal nanoparticles for the electrocatalytic reduction toward H2O2

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References

  1. Sitnikova NA, Borisova AV, Komkova MA, Karyakin AA (2011) Superstable advanced hydrogen peroxide transducer based on transition metal hexacyanoferrates. Anal Chem 83:2359–2363

    Article  CAS  Google Scholar 

  2. Karam P, Halaoui LI (2008) Sensing of H2O2 at low surface density assemblies of Pt nanoparticles in polyelectrolyte. Anal Chem 80:5441–5448

    Article  CAS  Google Scholar 

  3. Sang Y, Zhang L, Li YF, Chen LQ, Xu JL, Huang CZ (2010) A visual detection of hydrogen peroxide on the basis of Fenton reaction with gold nanoparticles. Anal Chim Acta 659:224–228

    Article  CAS  Google Scholar 

  4. Chen W, Cai S, Ren QQ, Wen W, Zhao YD (2012) Recent advances in electrochemical sensing for hydrogen peroxide: a review. Analyst 137:49–58

    Article  CAS  Google Scholar 

  5. Raoof JB, Ojani R, Hasheminejad E, Rashid-Nadimi S (2012) Electrochemical synthesis of Ag nanoparticles supported on glassy carbon electrode by means of p-isopropyl calix[6]arene matrix and its application for electrocatalytic reduction of H2O2. Appl Surf Sci 258:2788–2795

    Article  CAS  Google Scholar 

  6. Salimi A, Hallaj R, Soltanian S, Mamkhezri H (2007) Nanomolar detection of hydrogen peroxide on glassy carbon electrode modified with electrodeposited cobalt oxide nanoparticles. Anal Chim Acta 594:24–31

    Article  CAS  Google Scholar 

  7. Razmi H, Mohammad-Rezaei R, Heidari H (2009) Self-assembled prussian blue nanoparticles based electrochemical sensor for high sensitive determination of H2O2 in acidic media. Electroanalysis 21:2355–2362

    Article  CAS  Google Scholar 

  8. Liu Y, Wang DW, Xu L, Hou HQ, You TY (2011) A novel and simple route to prepare a Pt nanoparticle-loaded carbon nanofiber electrode for hydrogen peroxide sensing. Biosens Bioelectron 26:4585–4590

    Article  CAS  Google Scholar 

  9. Wang J, Musameh M, Lin YH (2003) Solubilization of carbon nanotubes by Nafion toward the preparation of amperometric biosensors. J Am Chem Soc 125:2408–2409

    Article  CAS  Google Scholar 

  10. Raffa D, Leung KT, Battaglini F (2003) A microelectrochemical enzyme transistor based on an N-alkylated poly(aniline) and its application to determine hydrogen peroxide at neutral pH. Anal Chem 75:4983–4987

    Article  CAS  Google Scholar 

  11. Wang F, Hu SS (2008) Direct electron-transfer of myoglobin within a new zwitterionic gemini surfactant film and its analytical application for H2O2 detection. Colloid Surf B 63:262–268

    Article  CAS  Google Scholar 

  12. Yu JH, Ju HX (2002) Preparation of porous titania sol–gel matrix for immobilization of horseradish peroxidase by a vapor deposition method. Anal Chem 74:3579–3583

    Article  CAS  Google Scholar 

  13. Cui K, Song YH, Yao Y, Huang ZZ, Wang L (2008) A novel hydrogen peroxide sensor based on Ag nanoparticles electrodeposited on DNA-networks modified glassy carbon electrode. Electrochem Commun 10:663–667

    Article  CAS  Google Scholar 

  14. Qian JH, Liu YC, Liu HY, Yu TY, Deng JQ (1997) Immobilization of horseradish peroxidase with a regenerated silk fibroin membrane and its application to a tetrathiafulvalene- mediating H2O2 sensor. Biosens Bioelectron 12:1213–1218

    Article  CAS  Google Scholar 

  15. Wang W, Zhang TJ, Zhang DW, Li HY, Ma YR, Qi LM, Zhou YL, Zhang XX (2011) Amperometric hydrogen peroxide biosensor based on the immobilization of heme proteins on gold nanoparticles-bacteria cellulose nanofibers nanocomposite. Talanta 84:71–77

    Article  CAS  Google Scholar 

  16. Choi MMF, Yiu TP (2004) Immobilization of beef liver catalase on eggshell membrane for fabrication of hydrogen peroxide biosensor. Enzyme Microb Tech 34:41–47

    Article  CAS  Google Scholar 

  17. Krajewska B (2004) Application of chitin- and chitosan-based materials for enzyme immobilizations: a review. Enzyme Microb Tech 35:126–139

    Article  CAS  Google Scholar 

  18. Guo SJ, Li J, Ren W, Wen D, Dong SJ, Wang EK (2009) Carbon nanotube/silica coaxial nanocable as a three-dimensional support for loading diverse ultra-high-density metal nanostructures: facile preparation and use as enhanced materials for electrochemical devices and SERS. Chem Mater 21:2247–2257

    Article  CAS  Google Scholar 

  19. Xiao F, Zhao FQ, Zhang YF, Guo GP, Zeng BZ (2009) Ultrasonic electrodeposition of gold-platinum alloy nanoparticles on ionic liquid-chitosan composite film and their application in fabricating nonenzyme hydrogen peroxide sensors. J Phys Chem C 113:849–855

    Article  CAS  Google Scholar 

  20. Wang J (2012) Electrochemical biosensing based on noble metal nanoparticles. Microchim Acta 177:245–270

    Article  CAS  Google Scholar 

  21. Wang F, Hu SS (2009) Electrochemical sensors based on metal and semiconductor nanoparticles. Microchim Acta 165:1–22

    Article  CAS  Google Scholar 

  22. Hernández-Santos D, González-García MB, García AC (2002) Metal-nanoparticles based electroanalysis. Electroanalysis 14:1225–1235

    Article  Google Scholar 

  23. Pingarrón JM, Yáñez-Sedeño P, González-Cortés A (2008) Gold nanoparticle- based electrochemical biosensors. Electrochim Acta 53:5848–5866

    Article  CAS  Google Scholar 

  24. Vidotti M, Carvalhal RF, Mendes RK, Ferreira DCM, Kubota LT (2011) Biosensors based on gold nanostructures. J Braz Chem Soc 22:3–20

    Article  CAS  Google Scholar 

  25. Rad AS, Mirabi A, Binaian E, Tayebi H (2011) A review on glucose and hydrogen peroxide biosensor based on modified electrode included silver nanoparticles. Int J Electrochem Sci 6:3671–3683

    CAS  Google Scholar 

  26. Schäferling M, Grögel DBM, Schreml S (2011) Luminescent probes for detection and imaging of hydrogen peroxide. Microchim Acta 174:1–18

    Article  CAS  Google Scholar 

  27. Lu Q, Li CM (2008) One-step co-electropolymerized conducting polymer–protein composite film for direct electrochemistry-based biosensors. Biosens Bioelectron 24:767–772

    Article  CAS  Google Scholar 

  28. Xiao Y, Ju HX, Chen HY (1999) Hydrogen peroxide sensor based on horseradish peroxidase-labeled Au colloids immobilized on gold electrode surface by cysteamine monolayer. Anal Chim Acta 391:73–82

    Article  CAS  Google Scholar 

  29. Chen XJ, Chen ZX, Zhu JW, Xu CB, Yan W, Yao C (2011) A novel H2O2 amperometric biosensor based on gold nanoparticles/self-doped polyaniline nanofibers. Bioelectrochemistry 82:87–94

    Article  CAS  Google Scholar 

  30. Lei CX, Hu SQ, Gao N, Shen GL, Yu RQ (2004) An amperometric hydrogen peroxide biosensor based on immobilizing horseradish peroxidase to a nano-Au monolayer supported by sol–gel derived carbon ceramic electrode. Bioelectrochemistry 65:33–39

    Article  CAS  Google Scholar 

  31. Gao FX, Yuan R, Chai YQ, Chen SH, Cao SR, Tang MY (2007) Amperometric hydrogen peroxide biosensor based on the immobilization of HRP on nano-Au/Thi/poly(p-aminobenzene sulfonic acid)-modified glassy carbon electrode. J Biochem Biophys Methods 70:407–413

    Article  CAS  Google Scholar 

  32. Chen SH, Yuan R, Chai YQ, Xu L, Wang N, Li XN, Zhang LY (2006) Amperometric bydrogen peroxide biosensor based on the immobilization of horseradish peroxidase (HRP) on the layer-by-layer assembly films of gold colloidal nanoparticles and toluidine blue. Electroanalysis 18:471–477

    Article  CAS  Google Scholar 

  33. Li WJ, Yuan R, Chai YQ, Zhou L, Chen SH, Li N (2008) Immobilization of horseradish peroxidase on chitosan/silica sol–gel hybrid membranes for the preparation of hydrogen peroxide biosensor. J Biochem Biophys Methods 70:830–837

    Article  CAS  Google Scholar 

  34. Li SF, Zhu XY, Zhang W, Xie GM, Feng WL (2012) Hydrogen peroxide biosensor based on gold nanoparticles/thionine/gold nanoparticles/multi-walled carbon nanotubes–chitosans composite film-modified electrode. Appl Surf Sci 258:2802–2807

    Article  CAS  Google Scholar 

  35. Kang XB, Pang GC, Liang XY, Wang M, Liu J, Zhu WM (2012) Study on a hydrogen peroxide biosensor based on horseradish peroxidase/GNPs-thionine/chitosan. Electrochim Acta 62:327–334

    Article  CAS  Google Scholar 

  36. Chen SH, Yuan R, Chai YQ, Li N (2008) A new enzyme immobilization technique based on thionine-bovine serum albumin conjugate and gold colloidal nanoparticles for reagentless amperometric biosensor applications. Electroanalysis 20:418–425

    Article  CAS  Google Scholar 

  37. Li WJ, Yuan R, Chai YQ, Hong CL, Zhuo Y (2008) Reagentless electrochemical hydrogen peroxide biosensor based on toluidine blue-derived organic material and functionalized gold nanoparticles. J Electrochem Soc 155:F97–F103

    Article  CAS  Google Scholar 

  38. Xuan J, Jia XD, Jing LP, Abdel-Halim ES, Zhu JJ (2012) Gold nanoparticle-assembled capsules and their application as hydrogen peroxide biosensor based on hemoglobin. Bioelectrochemistry 84:32–37

    Article  CAS  Google Scholar 

  39. Wang Y, Ma XL, Wen Y, Xing YY, Zhang ZR, Yang HF (2010) Direct electrochemistry and bioelectrocatalysis of horseradish peroxidase based on gold nano-seeds dotted TiO2 nanocomposite. Biosens Bioelectron 25:2442–2446

    Article  CAS  Google Scholar 

  40. Mathew M, Sandhyarani N (2011) A novel electrochemical sensor surface for the detection of hydrogen peroxide using cyclic bisureas/gold nanoparticle composite. Biosens Bioelectron 28:210–215

    Article  CAS  Google Scholar 

  41. Xu SY, Tu GL, Peng B, Han XZ (2006) Self-assembling gold nanoparticles on thiol-functionalized poly(styrene-co-acrylic acid) nanospheres for fabrication of a mediatorless biosensor. Anal Chim Acta 570:151–157

    Article  CAS  Google Scholar 

  42. Gu HY, Yu AM, Chen HY (2001) Direct electron transfer and characterization of hemoglobin immobilized on a Au colloid–cysteamine-modified gold electrode. J Electroanal Chem 516:119–126

    Article  CAS  Google Scholar 

  43. Yagati AK, Lee T, Min JH, Choi JW (2012) Electrochemical performance of gold nanoparticle–cytochrome c hybrid interface for H2O2 detection. Colloids Surf B 92:161–167

    Article  CAS  Google Scholar 

  44. Wang Y, Ma XL, Wen Y, Duan GP, Ren W, Zhang ZR, Yang HF (2009) Electrochemistry and electrocatalytic properties of mixed assemblies of horseradish peroxidase, poly(diallyl dimethylammonium chloride) and gold nanoparticles on a glassy carbon electrode. Microchim Acta 166:283–288

    Article  CAS  Google Scholar 

  45. Wang JW, Wang LP, Di JW, Tu YF (2009) Electrodeposition of gold nanoparticles on indium/tin oxide electrode for fabrication of a disposable hydrogen peroxide biosensor. Talanta 77:1454–1459

    Article  CAS  Google Scholar 

  46. Ju HX, Liu SQ, Ge BX, Lisdat F, Scheller FW (2002) Electrochemistry of cytochrome c immobilized on colloidal gold modified carbon paste electrodes and its electrocatalytic activity. Electroanalysis 14:141–147

    Article  CAS  Google Scholar 

  47. Li WT, Wang MH, Li YJ, Sun Y, Li JC (2011) Linker-free layer-by-layer self-assembly of gold nanoparticle multilayer films for direct electron transfer of horseradish peroxidase and H2O2 detection. Electrochim Acta 56:6919–6924

    Article  CAS  Google Scholar 

  48. Liu Y, Geng TM, Gao J (2008) Layer-by-layer immobilization of horseradish peroxidase on a gold electrode modified with colloidal gold nanoparticles. Microchim Acta 161:241–248

    Article  CAS  Google Scholar 

  49. Chen Y, Yang XJ, Guo LR, Li J, Xia XH, Zheng LM (2009) Direct electrochemistry and electrocatalysis of hemoglobin at three-dimensional gold film electrode modified with self-assembled monolayers of 3-mercaptopropylphosphonic acid. Anal Chim Acta 644:83–89

    Article  CAS  Google Scholar 

  50. Jia JB, Wang BQ, Wu AG, Cheng GJ, Li Z, Dong SJ (2002) A method to construct a third-generation horseradish peroxidase biosensor: self-assembling gold nanoparticles to three-dimensional sol–gel network. Anal Chem 74:2217–2223

    Article  CAS  Google Scholar 

  51. Zhu AW, Tian Y, Liu HQ, Luo YP (2009) Nanoporous gold film encapsulating cytochrome c for the fabrication of a H2O2 biosensor. Biomaterials 30:3183–3188

    Article  CAS  Google Scholar 

  52. Luo J, Dong MN, Lin FB, Liu ML, Tang H, Li HT, Zhang YY, Yao SZ (2011) Three-dimensional network polyamidoamine dendrimer-Au nanocomposite for the construction of a mediator-free horseradish peroxidase biosensor. Analyst 136:4500–4506

    Article  CAS  Google Scholar 

  53. Gao YC, Xi K, Wang WN, Jia XD, Zhu JJ (2011) A novel biosensor based on a gold nanoflowers/hemoglobin/carbon nanotubes modified electrode. Anal Methods 3:2387–2391

    Article  CAS  Google Scholar 

  54. Liu XQ, Feng HQ, Zhao RX, Wang YB, Liu XH (2012) A novel approach to construct a horseradish peroxidase hydrophilic ionic liquids Au nanoparticles dotted titanate nanotubes biosensor for amperometric sensing of hydrogen peroxide. Biosens Bioelectron 31:101–104

    Article  CAS  Google Scholar 

  55. Yin HS, Ai SY, Shi WJ, Zhu LS (2009) A novel hydrogen peroxide biosensor based on horseradish peroxidase immobilized on gold nanoparticles–silk fibroin modified glassy carbon electrode and direct electrochemistry of horseradish peroxidase. Sensor Actuat B 137:747–753

    Article  CAS  Google Scholar 

  56. Zhao XJ, Mai ZB, Kang XH, Zou XY (2008) Direct electrochemistry and electrocatalysis of horseradish peroxidase based on clay–chitosan-gold nanoparticle nanocomposite. Biosens Bioelectron 23:1032–1038

    Article  CAS  Google Scholar 

  57. Yarman A, Nagel T, Gajovic-Eichelmann N, Fischer A, Wollenberger U, Scheller FW (2011) Bioelectrocatalysis by microperoxidase-11 in a multilayer architecture of chitosan embedded gold nanoparticles. Electroanalysis 23:611–618

    CAS  Google Scholar 

  58. Qiu JD, Peng HP, Liang RP, Xia XH (2010) Facile preparation of magnetic core–shell Fe3O4@Au nanoparticle/myoglobin biofilm for direct electrochemistry. Biosens Bioelectron 25:1447–1453

    Article  CAS  Google Scholar 

  59. Yu CM, Guo JW, Gu HY (2009) Direct electrochemical behavior of hemoglobin at surface of Au@Fe3O4 magnetic nanoparticles. Microchim Acta 166:215–220

    Article  CAS  Google Scholar 

  60. Zhu WL, Wang YY, Xuan J, Zhang JR (2011) Fabrication of a novel hydrogen peroxide biosensor based on C@Au composite. J Nanosci Nanotechnol 11:138–142

    Article  CAS  Google Scholar 

  61. Chen SH, Yuan R, Chai YQ, Zhang LY, Wang N, Li XL (2007) Amperometric third-generation hydrogen peroxide biosensor based on the immobilization of hemoglobin on multiwall carbon nanotubes and gold colloidal nanoparticles. Biosens Bioelectron 22:1268–1274

    Article  CAS  Google Scholar 

  62. Wang YY, Chen XJ, Zhu JJ (2009) Fabrication of a novel hydrogen peroxide biosensor based on the AuNPs–C@SiO2 composite. Electrochem Commun 11:323–326

    Article  CAS  Google Scholar 

  63. Li F, Feng Y, Wang Z, Yang LM, Zhuo LH, Tang B (2010) Direct electrochemistry of horseradish peroxidase immobilized on the layered calcium carbonate–gold nanoparticles inorganic hybrid composite. Biosens Bioelectron 25:2244–2248

    Article  CAS  Google Scholar 

  64. Feng QL, Liu KP, Fu JJ, Zhang YZ, Zheng ZX, Wang CM, Du YL, Ye WC (2012) Direct electrochemistry of hemoglobin based on nano-composite film of gold nanopaticles and poly (diallyldimethylammonium chloride) functionalized grapheme. Electrochim Acta 60:304–308

    Article  CAS  Google Scholar 

  65. Huang KJ, Niu DJ, Liu X, Wu ZW, Fan Y, Chang YF, Wu YY (2011) Direct electrochemistry of catalase at amine-functionalized graphene/gold nanoparticles composite film for hydrogen peroxide sensor. Electrochim Acta 56:2947–2953

    Article  CAS  Google Scholar 

  66. Yan W, Feng XM, Chen XJ, Hou WH, Zhu JJ (2008) A super highly sensitive glucose biosensor based on Au nanoparticles–AgCl@polyaniline hybrid material. Biosens Bioelectron 23:925–931

    Article  CAS  Google Scholar 

  67. Zhu AW, Luo YP, Tian Y (2009) Plasmon-induced enhancement in analytical performance based on gold nanoparticles deposited on TiO2 film. Anal Chem 81:7243–7247

    Article  CAS  Google Scholar 

  68. Gu ZG, Yang SP, Li ZJ, Sun XL, Wang GL, Fang YJ, Liu JK (2011) An ultrasensitive hydrogen peroxide biosensor based on electrocatalytic synergy of graphene–gold nanocomposite, CdTe–CdS core–shell quantum dots and gold nanoparticles. Anal Chim Acta 701:75–80

    Article  CAS  Google Scholar 

  69. Gan X, Liu T, Zhong J, Liu XJ, Li GX (2004) Effect of silver nanoparticles on the electron transfer reactivity and the catalytic activity of myoglobin. ChemBioChem 5:1686–1691

    Article  CAS  Google Scholar 

  70. Yuan R, Liu Y, Li QF, Chai YQ, Mo CL, Zhong X, Tang DP, Dai JY (2005) Electrochemical characteristics of a platinum electrode modified with a matrix of polyvinyl butyral and colloidal Ag containing immobilized horseradish peroxidase. Anal Bioanal Chem 381:762–768

    Article  CAS  Google Scholar 

  71. Liu Y, Hu LM, Yang SQ (2008) Amplification of bioelectrocatalytic signalling based on silver nanoparticles and DNA-derived horseradish peroxidase biosensors. Microchim Acta 160:357–365

    Article  CAS  Google Scholar 

  72. Ren CB, Song YH, Li Z, Zhu GY (2005) Hydrogen peroxide sensor based on horseradish peroxidase immobilized on a silver nanoparticles/cysteamine/gold electrode. Anal Bioanal Chem 381:1179–1185

    Article  CAS  Google Scholar 

  73. Zhang F, Wu J, Zhang HB (2012) Construction of hyaluronan-silver nanoparticle–hemoglobin multilayer composite film and investigations on its electrocatalytic properties. J Solid State Electrochem 16:1683–1692

    Article  CAS  Google Scholar 

  74. Feng XM, Cheng YF, Ye C, Ye JS, Peng JY, Hu JP (2012) Synthesis and Ag-content-depended electrochemical properties of Ag/ZnO heterostructured nanomaterials. Mater Lett 79:205–208

    Article  CAS  Google Scholar 

  75. Wang YH, Gu HY (2009) Hemoglobin co-immobilized with silver–silver oxide nanoparticles on a bare silver electrode for hydrogen peroxide electroanalysis. Microchim Acta 164:41–47

    Article  CAS  Google Scholar 

  76. Li YC, Li YJ, Yang YY (2011) Direct electrochemistry and electrocatalysis of myoglobin-based nanocomposite membrane electrode. Bioelectrochemistry 82:112–116

    Article  CAS  Google Scholar 

  77. Wang FC, Yuan R, Chai YQ, Tang DP (2007) Probing traces of hydrogen peroxide by use of a biosensor based on mediator-free DNA and horseradish peroxidase immobilized on silver nanoparticles. Anal Bioanal Chem 387:709–717

    Article  CAS  Google Scholar 

  78. ElKaoutit M, Naggar AH, Naranjo-Rodríguez I, Hidalgo-Hidalgo de Cisneros JL (2012) Graphite grains studded with silver nanoparticles: Description and application in promoting direct biocatalysis between heme protein and the resulting carbon paste electrode. Colloid Surf B 92:42–49

    Article  CAS  Google Scholar 

  79. Wang YL, Tang M, Lin XH, Gao F, Li MG (2012) Sensor for hydrogen peroxide using a hemoglobin-modified glassy carbon electrode prepared by enhanced loading of silver nanoparticle onto carbon nanospheres via spontaneous polymerization of dopamine. Microchim Acta 176:405–410

    Article  CAS  Google Scholar 

  80. Mao CJ, Chen XB, Niu HL, Song JM, Zhang SY, Cui RJ (2012) A novel enzymatic hydrogen peroxide biosensor based on Ag/C nanocables. Biosens Bioelectron 31:544–547

    Article  CAS  Google Scholar 

  81. Liu YG, Zhang JJ, Hou WH, Zhu JJ (2008) A Pd/SBA-15 composite: synthesis, characterization and protein biosensing. Nanotechnology 19(135707):8

    Google Scholar 

  82. Sun AL, Sheng QL, Zheng JB (2012) A hydrogen peroxide biosensor based on direct electrochemistry of hemoglobin in palladium nanoparticles/graphene–chitosan nanocomposite film. Appl Biochem Biotechnol 166:764–773

    Article  CAS  Google Scholar 

  83. Wei CM, Yang M, Hu JB, Li QL (2007) Electrocatalysis of horseradish peroxidase immobilized on cobalt nanoparticles modified ITO electrode. Anal Lett 40:3182–3194

    Article  CAS  Google Scholar 

  84. Sheng QL, Wang MZ, Zheng JB (2011) A novel hydrogen peroxide biosensor based on enzymatically induced deposition of polyaniline on the functionalized graphene–carbon nanotube hybrid materials. Sens Actuators B 160:1070–1077

    Article  CAS  Google Scholar 

  85. Che X, Yuan R, Chai YQ, Ma LP, Li WJ, Li JJ (2009) Hydrogen peroxide sensor based on horseradish peroxidase immobilized on an electrode modified with DNA-L-cysteine-gold-platinum nanoparticles in polypyrrole film. Microchim Acta 167:159–165

    Article  CAS  Google Scholar 

  86. He P, Liu HT, Li ZY, Liu Y, Xu XD, Li JH (2004) Electrochemical deposition of silver in room temperature ionic liquids and its surface-enhanced Raman scattering effect. Langmuir 20:10260–10267

    Article  CAS  Google Scholar 

  87. Song XC, Wang X, Zheng YF, Ma R, Yin HY (2011) A hydrogen peroxide electrochemical sensor based on Ag nanoparticles grown on ITO substrate. J Nanopart Res 13:5449–5455

    Article  CAS  Google Scholar 

  88. Safavi A, Maleki N, Farjami E (2009) Electrodeposited silver nanoparticles on carbon ionic liquid electrode for electrocatalytic sensing of hydrogen peroxide. Electroanalysis 21:1533–1538

    Article  CAS  Google Scholar 

  89. Wu S, Zhao HT, Ju HX, Shi CG, Zhao JW (2006) Electrodeposition of silver–DNA hybrid nanoparticles for electrochemical sensing of hydrogen peroxide and glucose. Electrochem Commun 8:1197–1203

    Article  CAS  Google Scholar 

  90. Bui MPN, Pham XH, Han KN, Li CA, Kim YS, Seong GH (2010) Electrocatalytic reduction of hydrogen peroxide by silver particles patterned on single-walled carbon nanotubes. Sens Actuators B 150:436–441

    Article  CAS  Google Scholar 

  91. Wang Q, Zheng JB (2010) Electrodeposition of silver nanoparticles on a zinc oxide film: improvement of amperometric sensing sensitivity and stability for hydrogen peroxide determination. Microchim Acta 169:361–365

    Article  CAS  Google Scholar 

  92. Wang L, Zhu HZ, Hou HQ, Zhang ZY, Xiao XP, Song YH (2010) A novel hydrogen peroxide sensor based on Ag nanoparticles electrodeposited on chitosan-graphene oxide/cysteamine-modified gold electrode. J Solid State Chem 16:1693–1700

    Google Scholar 

  93. Wang L, Zhu HZ, Song YH, Liu L, He ZF, Wan LL, Chen SH, Xiang Y, Chen SS, Chen J (2012) Architecture of poly(o-phenylenediamine)–Ag nanoparticle composites for a hydrogen peroxide sensor. Electrochim Acta 60:314–320

    Article  CAS  Google Scholar 

  94. Balamurugan A, Chen SM (2009) Silver nanograins incorporated PEDOT modified electrode for electrocatalytic sensing of hydrogen peroxide. Electroanalysis 21:1419–1423

    Article  CAS  Google Scholar 

  95. Chen HH, Zhang Z, Cai DQ, Zhang SY, Zhang BL, Tang JL, Wu ZY (2011) A hydrogen peroxide sensor based on Ag nanoparticles electrodeposited on natural nano-structure attapulgite modified glassy carbon electrode. Talanta 86:266–270

    Article  CAS  Google Scholar 

  96. Singh RP, Pandey AC (2011) Silver nanosieve using 1,2-benzenedicarboxylic acid: a sensor for detection of hydrogen peroxide. Anal Methods 3:586–592

    Article  CAS  Google Scholar 

  97. Yi QF, Niu FJ, Li L, Du RL, Zhou ZH, Liu XP (2011) Novel nanoporous silver particles for electro-reduction of hydrogen peroxide in alkaline media. J Electroanal Chem 654:60–65

    Article  CAS  Google Scholar 

  98. Lu WB, Liao F, Luo YL, Chang GH, Sun XP (2011) Hydrothermal synthesis of well-stable silver nanoparticles and their application for enzymeless hydrogen peroxide detection. Electrochim Acta 56:2295–2298

    Article  CAS  Google Scholar 

  99. Liu S, Tian JQ, Wang L, Li HL, Zhang YW, Sun XP (2010) Stable aqueous dispersion of graphene nanosheets: noncovalent functionalization by a polymeric reducing agent and their subsequent decoration with Ag nanoparticles for enzymeless hydrogen peroxide detection. Macromolecules 43:10078–10083

    Article  CAS  Google Scholar 

  100. Qin XY, Lu WB, Luo YL, Chang GH, Sun XP (2011) Preparation of Ag nanoparticle-decorated polypyrrole colloids and their application for H2O2 detection. Electrochem Commun 13:785–787

    Article  CAS  Google Scholar 

  101. Yao L, Yang WY, Yang J, He LH, Sun J, Song R, Ma Z, Huang W (2011) Preparation and catalytic ability to reduce hydrogen peroxide of Ag nanoparticles highly dispersed via hyperbranched copolymer. Nanoscale 3:916–918

    Article  CAS  Google Scholar 

  102. Tian JQ, Luo YL, Li HL, Lu WB, Chang GH, Qin XY, Sun XP (2011) Ag@poly(m-phenylenediamine)-Ag core–shell nanoparticles: one-step preparation, characterization, and their application for H2O2 detection. Catal Sci Tech 1:1393–1398

    Article  CAS  Google Scholar 

  103. Zhao W, Wang HC, Qin X, Wang XS, Zhao ZX, Miao ZY, Chen LL, Shan MM, Fang YX, Chen Q (2009) A novel nonenzymatic hydrogen peroxide sensor based on multi-wall carbon nanotube/silver nanoparticle nanohybrids modified gold electrode. Talanta 80:1029–1033

    Article  CAS  Google Scholar 

  104. Habibi B, Jahanbakhshi M, Pournaghi-Azar MH (2012) Voltammetric and amperometric determination of hydrogen peroxide using a carbon-ceramic electrode modified with a nanohybrid composite made from single-walled carbon nanotubes and silver nanoparticles. Microchim Acta 177:185–193

    Article  CAS  Google Scholar 

  105. Tian JQ, Liu S, Sun XP (2010) Supramolecular microfibrils of o-phenylenediamine dimers: oxidation-induced morphology change and the spontaneous formation of Ag nanoparticle decorated nanofibers. Langmuir 26:15112–15116

    Article  CAS  Google Scholar 

  106. He XS, Hu CG, Liu H, Du GJ, Xi Y, Jiang YF (2010) Building Ag nanoparticle 3D catalyst via Na2Ti3O7 nanowires for the detection of hydrogen peroxide. Sensor Actuat B 144:289–294

    Article  CAS  Google Scholar 

  107. Wang AJ, Liao QC, Feng JJ, Yan ZZ, Chen JR (2012) In situ synthesis of polydopamine–Ag hollow microspheres for hydrogen peroxide sensing. Electrochim Acta 61:31–35

    Article  CAS  Google Scholar 

  108. Lu WB, Luo YL, Chang GH, Sun XP (2011) Synthesis of functional SiO2-coated graphene oxide nanosheets decorated with Ag nanoparticles for H2O2 and glucose detection. Biosens Bioelectron 26:4791–4797

    Article  CAS  Google Scholar 

  109. Lin CY, Lai YH, Balamurugana A, Vittal R, Lin CW, Ho KC (2010) Electrode modified with a composite film of ZnO nanorods and Ag nanoparticles as a sensor for hydrogen peroxide. Talanta 82:340–347

    Article  CAS  Google Scholar 

  110. Liu S, Tian JQ, Wang L, Sun XP (2011) Microwave-assisted rapid synthesis of Ag nanoparticles/graphene nanosheet composites and their application for hydrogen peroxide detection. J Nanopart Res 13:4539–4548

    Article  CAS  Google Scholar 

  111. Zhai XR, Gao ZJ (2010) Prussian blue electrodeposited on nano Ag-coated multiwalled carbon nanotubes composite for the determination of hydrogen peroxide. Anal Sci 26:343–347

    Article  CAS  Google Scholar 

  112. Shukla VK, Yadav RS, Yadav P, Pandey AC (2012) Green synthesis of nanosilver as a sensor for detection of hydrogen peroxide in water. J Hazard Mater 213–214:161–166

    Article  CAS  Google Scholar 

  113. You JM, Kim D, Jeon S (2012) Electrocatalytic reduction of H2O2 by Pt nanoparticles covalently bonded to thiolated carbon nanostructures. Electrochim Acta 65:288–293

    Article  CAS  Google Scholar 

  114. Bian XJ, Lu XF, Jin E, Kong LR, Zhang WJ, Wang C (2010) Fabrication of Pt/polypyrrole hybrid hollow microspheres and their application in electrochemical biosensing towards hydrogen peroxide. Talanta 81:813–818

    Article  CAS  Google Scholar 

  115. Zhang J, Gao L (2010) Synthesis of highly dispersed platinum nanoparticles on multiwalled carbon nanotubes and their electrocatalytic activity toward hydrogen peroxide. J Alloy Compd 505:604–608

    Article  CAS  Google Scholar 

  116. Chakraborty S, Raj CR (2009) Pt nanoparticle-based highly sensitive platform for the enzyme-free amperometric sensing of H2O2. Biosens Bioelectron 24:3264–3268

    Article  CAS  Google Scholar 

  117. Li JJ, Yuan R, Chai YQ, Zhang TT, Che X (2010) Direct electrocatalytic reduction of hydrogen peroxide at a glassy carbon electrode modified with polypyrrole nanowires and platinum hollow nanospheres. Microchim Acta 171:125–131

    Article  CAS  Google Scholar 

  118. Dey RS, Raj CR (2010) Development of an amperometric cholesterol biosensor based on graphene-Pt nanoparticle hybrid material. J Phys Chem C 114:21427–21433

    Article  CAS  Google Scholar 

  119. Zhong HA, Yuan R, Chai YQ, Zhang Y, Wang CY, Jia F (2012) Non-enzymatic hydrogen peroxide amperometric sensor based on a glassy carbon electrode modified with an MWCNT/polyaniline composite film and platinum nanoparticles. Microchim Acta 176:389–395

    Article  CAS  Google Scholar 

  120. Fang YX, Zhang D, Qin X, Miao ZY, Takahashi S, Anzai J, Chen Q (2012) A non-enzymatic hydrogen peroxide sensor based on poly(vinyl alcohol)–multiwalled carbon nanotubes-platinum nanoparticles hybrids modified glassy carbon electrode. Electrochim Acta 70:266–271

    Article  CAS  Google Scholar 

  121. Zeng ZY, Zhou XZ, Huang X, Wang ZJ, Yang YL, Zhang QC, Boey F, Zhang H (2010) Electrochemical deposition of Pt nanoparticles on carbon nanotube patterns for glucose detection. Analyst 135:1726–1730

    Article  CAS  Google Scholar 

  122. Han JH, Boo H, Park S, Chung TD (2006) Electrochemical oxidation of hydrogen peroxide at nanoporous platinum electrodes and the application to glutamate microsensor. Electrochim Acta 52:1788–1791

    Article  CAS  Google Scholar 

  123. Jamal M, Xu J, Razeeb KM (2010) Disposable biosensor based on immobilisation of glutamate oxidase on Pt nanoparticles modified Au nanowire array electrode. Biosens Bioelectron 26:1420–1424

    Article  CAS  Google Scholar 

  124. Qiang LL, Vaddiraju S, Rusling JF, Papadimitrakopoulos F (2010) Highly sensitive and reusable Pt-black microfluidic electrodes for long-term electrochemical sensing. Biosens Bioelectron 26:682–688

    Article  CAS  Google Scholar 

  125. You T, Niwa O, Tomita M, Hirono S (2003) Characterization of platinum nanoparticle-embedded carbon film electrode and its detection of hydrogen peroxide. Anal Chem 75:2080–2085

    Article  CAS  Google Scholar 

  126. Xu FG, Sun YJ, Zhang Y, Shi Y, Wen ZW, Li Z (2011) Graphene–Pt nanocomposite for nonenzymatic detection of hydrogen peroxide with enhanced sensitivity. Electrochem Commun 13:1131–1134

    Article  CAS  Google Scholar 

  127. Guo SJ, Wen D, Zhai YM, Dong SJ, Wang EK (2010) Platinum nanoparticle ensemble-on-graphene hybrid nanosheet: one-pot, rapid synthesis, and used as new electrode material for electrochemical sensing. Acs Nano 4:3959–3968

    Article  CAS  Google Scholar 

  128. Zhang Y, Sun YJ, Liu ZL, Xu FG, Cui K, Shi Y, Wen ZW, Li Z (2011) Au nanocages for highly sensitive and selective detection of H2O2. J Electroanal Chem 656:23–28

    Article  CAS  Google Scholar 

  129. Won YH, Huh K, Stanciu LA (2011) Au nanospheres and nanorods for enzyme-free electrochemical biosensor applications. Biosens Bioelectron 26:4514–4519

    Article  CAS  Google Scholar 

  130. Zheng M, Li P, Yang C, Zhu H, Chen Y, Tang YW, Zhou YM, Lu TH (2012) Ferric ion immobilized on three-dimensional nanoporous gold films modfied with self-assembled monolayers for electrochemical detection of hydrogen peroxide. Analyst 137:1182–1189

    Article  CAS  Google Scholar 

  131. Kumar SA, Wang SF, Chang YT (2010) Poly(BCB)/Au-nanoparticles hybrid film modified electrode: preparation, characterization and its application as a non-enzymatic sensor. Thin Solid Films 518:5832–5838

    Article  CAS  Google Scholar 

  132. Zhang QX, Ren QQ, Miao YQ, Yuan JH, Wang KK, Li FH, Han DX, Niu L (2012) One-step synthesis of graphene/polyallylamine-Au nanocomposites and their electrocatalysis toward oxygen reduction. Talanta 89:391–395

    Article  CAS  Google Scholar 

  133. Zanardi C, Terzi F, Zanfrognini B, Pigani L, Seeber R, Lukkari J, Aaritalo T (2010) Effective catalytic electrode system based on polyviologen and Au nanoparticles multilayer. Sensor Actuat B 144:92–98

    Article  CAS  Google Scholar 

  134. Liu RJ, Li SW, Yu XL, Zhang GJ, Zhang SJ, Yao JN, Keita B, Nadjo L, Zhi LJ (2012) Facile synthesis of Au-nanoparticle/polyoxometalate/graphene tricomponent nanohybrids: an enzyme-free electrochemical biosensor for hydrogen peroxide. Small 8:1398–1406

    Article  CAS  Google Scholar 

  135. Lu XQ, Li Y, Zhang X, Du J, Zhou XB, Xue ZH, Liu XH (2012) A simple and an efficient strategy to synthesize multi-component nanocomposites for biosensor applications. Anal Chim Acta 711:40–45

    Article  CAS  Google Scholar 

  136. Kumar SS, Joseph J, Phani KL (2007) Novel method for deposition of gold-prussian blue nanocomposite films induced by electrochemically formed gold nanoparticles: characterization and application to electrocatalysis. Chem Mater 19:4722–4730

    Article  CAS  Google Scholar 

  137. Li NB, Park JH, Park K, Kwon SJ, Shin H, Kwak J (2008) Characterization and electrocatalytic properties of Prussian blue electrochemically deposited on nano-Au/PAMAM dendrimer-modified gold electrode. Biosens Bioelectron 23:1519–1526

    Article  CAS  Google Scholar 

  138. Kong LR, Lu XF, Bian XJ, Zhang WJ, Wang C (2010) Accurately tuning the dispersity and size of palladium particles on carbon spheres and using carbon spheres/palladium composite as support for polyaniline in H2O2 electrochemical sensing. Langmuir 26:5985–5990

    Article  CAS  Google Scholar 

  139. Bo XJ, Bai J, Ju J, Guo LP (2010) A sensitive amperometric sensor for hydrazine and hydrogen peroxide based on palladium nanoparticles/onion-like mesoporous carbon vesicle. Anal Chim Acta 675:29–35

    Article  CAS  Google Scholar 

  140. Zhou P, Dai ZH, Fang M, Huang XH, Bao JC, Gong JF (2007) Novel dendritic palladium nanostructure and its application in biosensing. J Phys Chem C 111:12609–12616

    Article  CAS  Google Scholar 

  141. Yi QF, Niu FJ (2011) Novel nanoporous palladium catalyst for electroreduction of hydrogen peroxide. Rare Metals 30:332–336

    Article  CAS  Google Scholar 

  142. Gutes A, Laboriante L, Carraro C, Maboudian R (2010) Palladium nanostructures from galvanic displacement as hydrogen peroxide sensor. Sensor Actuat B 147:681–686

    Article  CAS  Google Scholar 

  143. Pournaghi-Azar MH, Ahour F, Pournaghi-Azar F (2010) Simple and rapid amperometric monitoring of hydrogen peroxide in salivary samples of dentistry patients exploiting its electro-reduction on the modified/palladized aluminum electrode as an improved electrocatalyst. Sensor Actuat B 145:334–339

    Article  CAS  Google Scholar 

  144. Shao CY, Lu N, Deng ZX (2009) DNA-assisted electroless deposition of highly dispersed palladium nanoparticles on glassy carbon surface: preparation and electrocatalytic properties. J Electroanal Chem 629:15–22

    Article  CAS  Google Scholar 

  145. You JM, Jeong YN, Ahmed MS, Kim SK, Choi HC, Jeon S (2011) Reductive determination of hydrogen peroxide with MWCNTs-Pd nanoparticles on a modified glassy carbon electrode. Biosens Bioelectron 26:2287–2291

    Article  CAS  Google Scholar 

  146. Wu S, Wu J, Liu YY, Ju HX (2008) Conductive and highly catalytic nanocage for assembly and improving function of enzyme. Chem Mater 20:1397–1403

    Article  CAS  Google Scholar 

  147. Han M, Liu S, Bao JC, Dai ZH (2012) Pd nanoparticle assemblies-As the substitute of HRP, in their biosensing applications for H2O2 and glucose. Biosens Bioelectron 31:151–156

    Article  CAS  Google Scholar 

  148. Qiu R, Cha HG, Noh HB, Shim YB, Zhang XL, Qiao R, Zhang D, Kim Y, Pal U, Kang YS (2009) Preparation of dendritic copper nanostructures and their characterization for electroreduction. J Phys Chem C 113:15891–15896

    Article  CAS  Google Scholar 

  149. Selvaraju T, Ramaraj R (2009) Electrocatalytic reduction of hydrogen peroxid at nanostructured copper modified electrode. J Appl Electrochem 39:321–327

    Article  CAS  Google Scholar 

  150. Kumar SA, Lo PH, Chen SM (2009) Electrochemical analysis of H2O2 and nitrite using copper nanoparticles/poly(o-phenylenediamine) film modified glassy carbon electrode. J Electrochem Soc 156:E118–E123

    Article  CAS  Google Scholar 

  151. Zhang TT, Yuan R, Chai YQ, Li WJ, Ling SJ (2008) A novel nonenzymatic hydrogen peroxide sensor based on a polypyrrole nanowire-copper nanocomposite modified gold electrode. Sensors 8:5141–5152

    Article  CAS  Google Scholar 

  152. Tsai TH, Chen TW, Chen SM (2011) Copper nanoparticles with copper hexacyanoferrate and poly(3,4-ethylenedioxythiophene) hybrid film modified electrode for hydrogen peroxide detection. Int J Electrochem Sci 6:4628–4637

    CAS  Google Scholar 

  153. Annamalai SK, Palani B, Pillai KC (2012) Highly stable and redox active nano copper species stabilized functionalized-multiwalled carbon nanotube/chitosan modified electrode for efficient hydrogen peroxide detection. Colloid Surf A 395:207–216

    Article  CAS  Google Scholar 

  154. You TY, Niwa O, Kurita R, Iwasaki Y, Hayashi K, Suzuki K, Hirono S (2004) Reductive H2O2 detection at nanoparticle iridium/carbon film electrode and its application as L-glutamate enzyme sensor. Electroanalysis 16:54–59

    Article  CAS  Google Scholar 

  155. Chandra S, Lokesh KS, Nicolai A, Lang H (2009) Dendrimer-rhodium nanoparticle modified glassy carbon electrode for amperometric detection of hydrogen peroxide. Anal Chim Acta 632:63–68

    Article  CAS  Google Scholar 

  156. Chen KJ, Pillai KC, Rick J, Pan CJ, Wang SH, Liu CC, Hwang BJ (2012) Bimetallic PtM (M = Pd, Ir) nanoparticle decorated multi-walled carbon nanotube enzyme-free, mediator-less amperometric sensor for H2O2. Biosens Bioelectron 33:120–127

    Article  CAS  Google Scholar 

  157. Yu YY, Sun Q, Liu XQ, Wu HH, Zhou TS, Shi GY (2011) Size-controllable gold–platinum alloy nanoparticles on nine functionalized ionic-liquid surfaces and their application as electrocatalysts for hydrogen peroxide reduction. Chem Eur J 17:11314–11323

    Article  CAS  Google Scholar 

  158. Chen KJ, Lee CF, Rick J, Wang SH, Liu CC, Hwang BJ (2012) Fabrication and application of amperometric glucose biosensor based on a novel PtPd bimetallic nanoparticle decorated multi-walled carbon nanotube catalyst. Biosens Bioelectron 33:75–81

    Article  CAS  Google Scholar 

  159. Wang L, Wang F, Shang L, Zhu CZ, Ren W, Dong SJ (2010) AuAg bimetallic nanoparticles film fabricated based on H2O2-mediated silver reduction and its application. Talanta 82:113–117

    Article  CAS  Google Scholar 

  160. Tsai TH, Thiagarajan S, Chen SM (2010) Green synthesized Au–Ag bimetallic nanoparticles modified electrodes for the amperometric detection of hydrogen peroxide. J Appl Electrochem 40:2071–2076

    Article  CAS  Google Scholar 

  161. Manivannan S, Ramaraj R (2009) Core–shell Au/Ag nanoparticles embedded in silicate sol–gel network for sensor application towards hydrogen peroxide. J Chem Sci 121:735–743

    Article  CAS  Google Scholar 

  162. Kang Q, Yang LX, Cai QY (2008) An electro-catalytic biosensor fabricated with Pt–Au nanoparticle-decorated titania nanotube array. Bioelectrochemistry 74:62–65

    Article  CAS  Google Scholar 

  163. Niu XH, Chen C, Zhao HL, Chai Y, Lan MB (2012) Novel snowflake-like Pt-Pd bimetallic clusters on screen-printed gold nanofilm electrode for H2O2 and glucose sensing. Biosens Bioelectron 36:262–266

    Article  CAS  Google Scholar 

  164. Xu CX, Liu YQ, Su F, Liu AH, Qiu HJ (2011) Nanoporous PtAg and PtCu alloys with hollow ligaments for enhanced electrocatalysis and glucose biosensing. Biosens Bioelectron 27:160–166

    Article  CAS  Google Scholar 

  165. Wang H, Bo XG, Bai J, Wang LX, Guo LP (2011) Electrochemical applications of platinum–palladium alloy nanoparticles/large mesoporous carbon. J Electroanal Chem 662:281–287

    Article  CAS  Google Scholar 

  166. Liu AH, Geng HR, Xu CX, Qiu HJ (2011) A three-dimensional hierarchical nanoporous PdCu alloy for enhanced electrocatalysis and biosensing. Anal Chim Acta 703:172–178

    Article  CAS  Google Scholar 

  167. Rajkumar M, Thiagarajan S, Chen SM (2011) Electrochemical fabrication of Rh–Pd particles and electrocatalytic applications. J Appl Electrochem 41:663–668

    Article  CAS  Google Scholar 

  168. Janasek D, Vastarella W, Teuscher USN, Heilmann A (2002) Ruthenium/rhodium modified gold electrodes for the amperometric detection of hydrogen peroxide at low potentials. Anal Bioanal Chem 374:1267–1273

    Article  CAS  Google Scholar 

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Acknowledgments

This work is supported by National Natural Science Foundation of China (21075100, 21275119), Ministry of Education of China (708073), Specialized Research Fund for the Doctoral Program of Higher Education (20100182110015), State Key Laboratory of Electroanalytical Chemistry (SKLEAC 2010009), Natural Science Foundation Project of Chongqing City (CSTC-2011BA7003, CSTC-2009BA1003) and Fundamental Research Funds for the Central Universities (XDJK2012A004).

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  1. Education Ministry Key Laboratory on Luminescence and Real-Time Analysis, School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, China

    Shihong Chen, Ruo Yuan & Yaqin Chai

  2. Chongqing Key Laboratory for Advanced Materials & Technologies of Clean Energies, Institute for Clean Energy & Advanced Materials, Southwest University, Chongqing, 400715, People’s Republic of China

    Fangxin Hu

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  1. Shihong Chen
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  2. Ruo Yuan
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Correspondence to Ruo Yuan.

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Chen, S., Yuan, R., Chai, Y. et al. Electrochemical sensing of hydrogen peroxide using metal nanoparticles: a review. Microchim Acta 180, 15–32 (2013). https://doi.org/10.1007/s00604-012-0904-4

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