Microchimica Acta

, Volume 179, Issue 1–2, pp 157–161 | Cite as

Non-enzymatic analysis of glucose on printed films based on multi-walled carbon nanotubes

  • Nikos G. Tsierkezos
  • Uwe Ritter
  • Nora Wetzold
  • Arved Carl Hübler
Original Paper


We report on the fabrication of an enzyme–free electrochemical sensor for glucose based on a printed film consisting of multi–walled carbon nanotubes (MWCNTs). The MWCNT–based film can be produced by means of a flexographic printing process on a polycarbonate (PC) substrate. The electrochemical response of the MWCNT–based film (referred to as MWCNT–PC) towards the oxidation of glucose at pH 7 was studied by means of cyclic voltammetry and electrochemical impedance spectroscopy. The MWCNT–PC film exhibits substantial electrocatalytic activity towards the oxidation of glucose at an anodic potential of 0.30 V (vs. Ag/AgCl). The findings reveal that the MWCNT–PC film enables non–enzymatic sensing of glucose with a detection limit as low as 2.16 μM and a sensitivity of 1045 μA∙mM−1∙cm−2.


Enzyme–free electrochemical sensor for glucose consisting of multi–walled carbon nanotubes was fabricated by means of flexographic printing process on polycarbonate substrate. The sensor exhibits electrocatalytic activity for glucose oxidation at an anodic potential of 0.30 V (vs. Ag/AgCl) with detection limit of 2.16 μM and sensitivity of 1045 μA∙mM−1∙cm−2.


Enzyme-free sensor Glucose Multi-walled carbon nanotubes Flexographic printing process Polycarbonate substrate 

Supplementary material

604_2012_881_MOESM1_ESM.docx (1.3 mb)
ESM 1(DOCX 1295 kb)


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Copyright information

© Springer-Verlag 2012

Authors and Affiliations

  • Nikos G. Tsierkezos
    • 1
  • Uwe Ritter
    • 1
  • Nora Wetzold
    • 2
  • Arved Carl Hübler
    • 2
  1. 1.Institut für Chemie und BiotechnikTechnische Universität IlmenauIlmenauGermany
  2. 2.Institut für Print- und Medientechnik, Fakultät für MaschinenbauTechnische Universität ChemnitzChemnitzGermany

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