Non-enzymatic analysis of glucose on printed films based on multi-walled carbon nanotubes
We report on the fabrication of an enzyme–free electrochemical sensor for glucose based on a printed film consisting of multi–walled carbon nanotubes (MWCNTs). The MWCNT–based film can be produced by means of a flexographic printing process on a polycarbonate (PC) substrate. The electrochemical response of the MWCNT–based film (referred to as MWCNT–PC) towards the oxidation of glucose at pH 7 was studied by means of cyclic voltammetry and electrochemical impedance spectroscopy. The MWCNT–PC film exhibits substantial electrocatalytic activity towards the oxidation of glucose at an anodic potential of 0.30 V (vs. Ag/AgCl). The findings reveal that the MWCNT–PC film enables non–enzymatic sensing of glucose with a detection limit as low as 2.16 μM and a sensitivity of 1045 μA∙mM−1∙cm−2.
KeywordsEnzyme-free sensor Glucose Multi-walled carbon nanotubes Flexographic printing process Polycarbonate substrate
- 2.Reach G, Wilson GS (1992) Can continuous glucose monitoring be used for the treatment of diabetes. Anal Chem 64:381–386Google Scholar
- 3.Kuhn LS (1998) Biosensors: blockbuster or bomb? Electrochemical biosensors for diabetes monitoring. Electrochem Soc Interface 7:26–33Google Scholar
- 24.Tsierkezos NG, Ritter U (2012) Simultaneous detection of ascorbic acid and uric acid at MWCNT modified electrodes. J Nanosci Lett 2:25 (12 pages)Google Scholar
- 28.Tsierkezos NG, Wetzold N, Ritter U (2012) Electrochemical responses of carbon nanotubes-based films printed on polymer substances. Ionics. doi:10.1007/s11581-012-0729-5
- 30.Danaee I, Jafarian M, Forouzandeh F, Gobal F (2012) Kinetic studies of glucose electrocatalytic oxidation on GC/Ni electrode. Int J Chem Kinet. doi:10.1002/kin.20721