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A novel one-step electrochemical codeposition of carbon nanotubes-DNA hybrids and tiron doped polypyrrole for selective and sensitive determination of dopamine

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Abstract

We describe a novel sensor for dopamine. It is based on the use of polypyrrole doped with a carbon nanotube-DNA hybrid. The composite material can be used as a matrix for immobilizing doping anions such as tiron which assist in electrostatic repulsion of anions such as ascorbate and others. The sensor was used for highly selective and sensitive determination of dopamine. Parameters affecting the response were optimized. The sensor displays a wide dynamic range, a detection limit as low as 0.5 pM, high stability, and good reproducibility.

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Acknowledgements

The financial support from National Outstanding Youth Foundations of China, National Science Foundation of China (50725825) and Special Research Found for the Doctoral Program of Higher Education of China (20060532006) is acknowledged.

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Authors and Affiliations

  1. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China

    Jing Li, Wanzhi Wei & Shenglian Luo

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  1. Jing Li
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  2. Wanzhi Wei
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  3. Shenglian Luo
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Correspondence to Shenglian Luo.

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Li, J., Wei, W. & Luo, S. A novel one-step electrochemical codeposition of carbon nanotubes-DNA hybrids and tiron doped polypyrrole for selective and sensitive determination of dopamine. Microchim Acta 171, 109–116 (2010). https://doi.org/10.1007/s00604-010-0412-3

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  • DOI: https://doi.org/10.1007/s00604-010-0412-3

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