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Development and application of a nano-alumina based nitric oxide sensor

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Abstract

A novel sensor is described for the sensitive determination of nitric oxide (NO) based on a nano-alumina (nano-Al2O3) modified glassy carbon electrode. Cyclic voltammetry, chronocoulometry and linear sweep voltammetry were used to investigate the electrochemical response of the sensor and the reaction mechanism of NO at the nano-Al2O3 film based sensor. The surface morphologies of different electrodes were characterized by scanning electron microscopy. Under optimal working conditions, the peak current of NO oxidation linearly increased with its concentration in the range 0.04∼210 μmol L−1 with a detection limit of 7.2 nM. The nano-Al2O3 film based sensor was applied to the determination of NO released from rat lung, and the results were satisfactory, which indicates that it may have practical applications in NO monitoring systems.

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Acknowledgements

This research is supported by the Nature Science Foundation of Education Department of Yunnan Province of China (No. 06Z048A), National Nature Science Foundation of China (Nos. 60571042 and 30770549) and the Physical Chemistry Key Discipline Construction Fund Grants of Yunnan Province of China.

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Authors and Affiliations

  1. Department of Chemistry, Qujing Normal College, Qujing, 655011, China

    Qiong He

  2. College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, 430072, China

    Qiong He, Dongyun Zheng & Shengshui Hu

  3. State Key Laboratory of Transducer Technology, Chinese Academy of Sciences, Beijing, 100080, China

    Qiong He & Shengshui Hu

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  1. Qiong He
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  2. Dongyun Zheng
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  3. Shengshui Hu
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Correspondence to Shengshui Hu.

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He, Q., Zheng, D. & Hu, S. Development and application of a nano-alumina based nitric oxide sensor. Microchim Acta 164, 459–464 (2009). https://doi.org/10.1007/s00604-008-0086-2

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