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Oxygen plasma-treated gold nanoparticle-based field-effect devices as transducer structures for bio-chemical sensing

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Abstract

EIS (electrolyte-insulator-semiconductor) sensors based on the functionalization of uncoated gold nanoparticles supported on a Si/SiO2 structure are presented. Oxygen plasma etching at moderate power (<200 W) provides a convenient and efficient way to remove organic capping agents from the gold nanoparticles without significant damage. Higher power intensities destroy the linkage between the SiO2 and the gold nanoparticles, and some of the gold nanoparticles are removed from the surface. The flat-band potential shift, i.e. the pH dependence of the gold-coated EIS sensors is similar (33 mV/pH) to the uncoated EIS pH-sensor. Lead, penicillin and glucose sensors were prepared by immobilization of β-cyclodextrin, penicillinase and glucose oxidase by various immobilization techniques.

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Acknowledgements

The authors are grateful for the technical assistance of H.-P. Bochem and A. Besmehn for the surface characterization with HRSEM and XPS and to A. Voskevich for the very useful discussions. J. Gun thanks the Alexander von Humboldt Foundation for the financial support.

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Authors and Affiliations

  1. Institute of Chemistry, The Hebrew University of Jerusalem, Givat Ram, Jerusalem, IL-91904, Israel

    Jenny Gun, Dan Rizkov & Ovadia Lev

  2. Institute of Nano- and Biotechnologies (INB), Aachen University of Applied Sciences, Campus Jülich, Ginsterweg 1, DE-52428, Jülich, Germany

    Jenny Gun

  3. Research Centre Jülich, Institute of Bio- and Nanosystems (IBN2), DE-52425, Jülich, Germany

    Maryam H. Abouzar, Arshak Poghossian & Michael J. Schöning

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  1. Jenny Gun
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  2. Dan Rizkov
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  3. Ovadia Lev
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  4. Maryam H. Abouzar
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  5. Arshak Poghossian
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  6. Michael J. Schöning
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Correspondence to Ovadia Lev or Michael J. Schöning.

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Gun, J., Rizkov, D., Lev, O. et al. Oxygen plasma-treated gold nanoparticle-based field-effect devices as transducer structures for bio-chemical sensing. Microchim Acta 164, 395–404 (2009). https://doi.org/10.1007/s00604-008-0073-7

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  • DOI: https://doi.org/10.1007/s00604-008-0073-7

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