Skip to main content
SpringerLink
Log in

Electrogenerated Chemiluminescence (ECL) Determination of Ephedrine with a Self-Assembly Multilayer Ni(II)-Polyluminol Modified Electrode

  • Original Paper
  • Published:
Microchimica Acta Aims and scope Submit manuscript

Abstract.

By combining the layer-by-layer (LBL) self-assembly technique with the electrochemical polymerization method, multilayer Ni(II)-polyluminol films were modified on the surface of a vaseline-impregnated graphite electrode. It was found that, compared with an electrode modified by direct electrochemical polymerization, this modified electrode offered a suitable ECL reaction micro-environment created by the special multilayer films, which was beneficial to the ephedrine hydrochloride enhancing effect for luminol ECL intensity. The ECL enhancing effect of ephedrine hydrochloride on the electro-oxidation luminol was improved on this modified electrode. Based on this finding, a new sensitive ECL method was developed for ephedrine hydrochloride determination under the optimal conditions. At the same time, a new idea is proposed for improving the analytical performance of the luminol ECL system by modifying the ECL reaction micro-environment with the layer-by-layer self- assembly method. Under the optimum experimental conditions, the ephedrine hydrochloride concentration in the range of 2.0 × 10−8–7.0 × 10−6 mol L−1 was proportional to the enhanced ECL signal, and it offered an 8.0 × 10−9 mol L−1 detection limit for ephedrine hydrochloride.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • G B Li Z P Zhang X G Chen Z D Hu Z F Zhao M Hooper (1999) Talanta 48 1023 Occurrence Handle1:CAS:528:DyaK1MXit1OnsLo%3D

    CAS  Google Scholar 

  • D P Nikolelis S E Petropoulou G Theoharis (2002) Electrochim Acta 47 3457 Occurrence Handle10.1016/S0013-4686(02)00282-7 Occurrence Handle1:CAS:528:DC%2BD38Xmt1yhsL8%3D

    Article  CAS  Google Scholar 

  • G Aymard B Labarthe D Warot I Berlin B Diquet (2000) B Biomed Appl 744 25 Occurrence Handle1:CAS:528:DC%2BD3cXks12mtbg%3D

    CAS  Google Scholar 

  • Y Wang D S Fice P K F Yeung (1999) J Pharm Biomed Anal 21 519 Occurrence Handle10.1016/S0731-7085(99)00117-X Occurrence Handle1:CAS:528:DC%2BD3cXhtVyqug%3D%3D

    Article  CAS  Google Scholar 

  • P Van Eenoo F T Delbeke K Roels P De Backer (2001) J Chromatogr B 760 255 Occurrence Handle1:CAS:528:DC%2BD3MXlsFykurw%3D

    CAS  Google Scholar 

  • M H E Spyridaki C J Tsitsimpikou P A Siskos C G Georgakopoulos (2001) J Chromatogr B 758 311 Occurrence Handle1:CAS:528:DC%2BD3MXktV2nsbk%3D

    CAS  Google Scholar 

  • M Marazuela L Aqui A Gonzalez-Cortez P Yanez-Sedeno J M Pingarron (1999) Electroanalysis 11 1333 Occurrence Handle10.1002/(SICI)1521-4109(199912)11:18<1333::AID-ELAN1333>3.0.CO;2-6 Occurrence Handle1:CAS:528:DC%2BD3cXjtFKitA%3D%3D

    Article  CAS  Google Scholar 

  • D P Nikolelis S E Petropoulou G Theoharis (2002) Electrochim Acta 47 3457 Occurrence Handle10.1016/S0013-4686(02)00282-7 Occurrence Handle1:CAS:528:DC%2BD38Xmt1yhsL8%3D

    Article  CAS  Google Scholar 

  • N N Rozhitskii (1992) J Anal Chem USSR 47 1288

    Google Scholar 

  • A W Knight G M Greenway (1994) Analyst 119 879 Occurrence Handle10.1039/an9941900879 Occurrence Handle1:CAS:528:DyaK2cXlt1Cjt7s%3D

    Article  CAS  Google Scholar 

  • W Y Lee (1997) Mikrochim Acta 127 19 Occurrence Handle10.1007/BF01243160 Occurrence Handle1:CAS:528:DyaK2sXkvVeisLo%3D

    Article  CAS  Google Scholar 

  • L J Kricka P E Stanley (1999) Luminescence 14 107 Occurrence Handle1:STN:280:DC%2BD3czhtVKntg%3D%3D

    CAS  Google Scholar 

  • A W Knight (1999) Trends Anal Chem 18 47 Occurrence Handle10.1016/S0165-9936(98)00086-7 Occurrence Handle1:CAS:528:DyaK1MXltFShsw%3D%3D

    Article  CAS  Google Scholar 

  • R G Gerardi N W Barnett S W Lewis (1999) Anal Chim Acta 378 1 Occurrence Handle10.1016/S0003-2670(98)00545-5 Occurrence Handle1:CAS:528:DyaK1cXntVGjsrk%3D

    Article  CAS  Google Scholar 

  • K A Fähnrich M Pravda G G Guilbault (2001) Talanta 54 531 Occurrence Handle10.1016/S0039-9140(01)00312-5

    Article  Google Scholar 

  • M M Richter (2004) Chem Rev 104 3003 Occurrence Handle10.1021/cr020373d Occurrence Handle1:CAS:528:DC%2BD2cXitlWmsLw%3D

    Article  CAS  Google Scholar 

  • M Yamada S Suzuki (1984) Anal Letter 17 251 Occurrence Handle1:CAS:528:DyaL2cXksVOrtLY%3D

    CAS  Google Scholar 

  • M Yamada T Hobo (1995) Dojin News 54 3

    Google Scholar 

  • K Matsue M Yadama T Suzuki T Hobo (1989) Anal Letter 22 2445 Occurrence Handle1:CAS:528:DyaK3cXntVWnsw%3D%3D

    CAS  Google Scholar 

  • Z J Gao C W Lau J Z Lu (2004) Analyst 129 1262

    Google Scholar 

  • G P Jirka A F Martin T A Nieman (1993) Anal Chim Acta 284 345 Occurrence Handle10.1016/0003-2670(93)85319-F Occurrence Handle1:CAS:528:DyaK2cXhsFant74%3D

    Article  CAS  Google Scholar 

  • B Leca L Blum (2000) J Analyst 125 789 Occurrence Handle1:CAS:528:DC%2BD3cXivFemtr0%3D

    CAS  Google Scholar 

  • S Sakura H Imai (1988) Anal Sci 4 9 Occurrence Handle1:CAS:528:DyaL1cXhsVansLk%3D

    CAS  Google Scholar 

  • C A Marquette L Blum (1999) J Anal Chim Acta 381 1 Occurrence Handle1:CAS:528:DyaK1MXhsVSlsQ%3D%3D

    CAS  Google Scholar 

  • R Wilson D J Schiffrin (1998) J Electroanal Chem 448 125 Occurrence Handle10.1016/S0022-0728(98)00024-2 Occurrence Handle1:CAS:528:DyaK1cXivF2rsL0%3D

    Article  CAS  Google Scholar 

  • C E Taylor SuffixIV S E Creager (2000) J Electroanal Chem 485 114 Occurrence Handle10.1016/S0022-0728(00)00097-8 Occurrence Handle1:CAS:528:DC%2BD3cXkslKit7w%3D

    Article  CAS  Google Scholar 

  • C S Ouyang C M Wang (1998) J Electrochem Soc 145 2654 Occurrence Handle1:CAS:528:DyaK1cXltFGgtbc%3D

    CAS  Google Scholar 

  • C S Ouyang C M Wang (1999) J Electroanal Chem 474 82

    Google Scholar 

  • L D Zhu Y X Li G Y Zhu (2002) Sens Actuators B 86 209 Occurrence Handle10.1016/S0925-4005(02)00173-9

    Article  Google Scholar 

  • L D Zhu Y X Li G Y Zhu (2004) Sens Actuators B 98 115 Occurrence Handle10.1016/S0925-4005(03)00640-3

    Article  Google Scholar 

  • L D Zhu Y X Li F M Tian B Xu G Y Zhu (2002) Sens Actuators B 84 265 Occurrence Handle10.1016/S0925-4005(01)01080-2

    Article  Google Scholar 

  • X W Zheng Z J Zhang Q Wang (2003) Chem J Chinese Universities 24 1385 Occurrence Handle1:CAS:528:DC%2BD3sXmvVymt7o%3D

    CAS  Google Scholar 

  • G F Zhang H Y Chen (2000) Anal Chim Acta 419 25 Occurrence Handle1:CAS:528:DC%2BD3cXlsFGrsbg%3D

    CAS  Google Scholar 

  • J H Li G J Cheng S J Dong (1996) Fenxi Huaxue 24 1093 Occurrence Handle1:CAS:528:DyaK28XlvFOntb8%3D

    CAS  Google Scholar 

  • I Willner A Riklin (1994) Anal Chem 66 1535 Occurrence Handle10.1021/ac00081a028 Occurrence Handle1:CAS:528:DyaK2cXis1Cqs7k%3D

    Article  CAS  Google Scholar 

  • I Wllner V Heleg-shabtai R Blonder (1996) J Am Chem Soc 118 10321

    Google Scholar 

  • A Riklin I Willner (1995) Anal Chem 67 4118 Occurrence Handle10.1021/ac00118a014 Occurrence Handle1:CAS:528:DyaK2MXosF2jsr8%3D

    Article  CAS  Google Scholar 

  • S E Creager K G Olsen (1995) Anal Chim Acta 307 277 Occurrence Handle10.1016/0003-2670(94)00506-H Occurrence Handle1:CAS:528:DyaK2MXlvFKjtbo%3D

    Article  CAS  Google Scholar 

  • S K Jung G S Wilson (1996) Anal Chem 68 591 Occurrence Handle10.1021/ac950424p Occurrence Handle1:CAS:528:DyaK28Xjt1OltQ%3D%3D

    Article  CAS  Google Scholar 

  • K Takehara Y Ide M Aihara (1992) Bioelectrochem Bioenerg 29 103 Occurrence Handle1:CAS:528:DyaK2cXivVyq

    CAS  Google Scholar 

  • N Ferreyra L Coche-Guérente P Labb (2004) Electrochimica Acta 49 477 Occurrence Handle10.1016/j.electacta.2003.09.004 Occurrence Handle1:CAS:528:DC%2BD3sXptlCju7c%3D

    Article  CAS  Google Scholar 

  • C Q Sun G J Liu H A Zhang (1998) Chem J Chinese Universities 19 382 Occurrence Handle1:CAS:528:DyaK1cXitV2mt7o%3D

    CAS  Google Scholar 

  • J H Yan J H Li S J Dong (1996) J Chem Soc 92 1001 Occurrence Handle1:CAS:528:DyaK28XitFaqtro%3D

    CAS  Google Scholar 

  • K Takethara H Takemura Y J Ide (1993) J Colloid Interface Sci 156 274

    Google Scholar 

  • L M Niu H Q Luo N B Li (2005) Microchim Acta 150 87 Occurrence Handle10.1007/s00604-005-0331-x Occurrence Handle1:CAS:528:DC%2BD2MXktlCit7k%3D

    Article  CAS  Google Scholar 

  • H Cui Y Xu Z F Zhang (2004) Anal Chem 76 4002 Occurrence Handle1:CAS:528:DC%2BD2cXltVCgt7c%3D

    CAS  Google Scholar 

  • Z H Guo Y Shen M K Wang F Zhao S J Dong (2004) Anal Chem 76 184 Occurrence Handle1:CAS:528:DC%2BD3sXpt1Wru7k%3D

    CAS  Google Scholar 

  • T Okajima T Ohsaka (2002) J Electroanal Chem 534 181 Occurrence Handle10.1016/S0022-0728(02)01098-7 Occurrence Handle1:CAS:528:DC%2BD38XotFOjt7w%3D

    Article  CAS  Google Scholar 

  • Y Sato K Uosaki (1993) Denki Kagaku (Electrochemistry) 61 816 Occurrence Handle1:CAS:528:DyaK3sXmsFygsbY%3D

    CAS  Google Scholar 

  • Y Sato K Uosaki (1995) J Electroanal Chem 384 57 Occurrence Handle10.1016/0022-0728(94)03731-H Occurrence Handle1:CAS:528:DyaK2MXkvFKju7w%3D

    Article  CAS  Google Scholar 

  • Y Sato T Sawaguchi F Mizutani (2001) Electrochem Com 3 131

    Google Scholar 

  • C E Taylor SuffixIV S E Creager (2000) J Electroanal Chem 485 114 Occurrence Handle10.1016/S0022-0728(00)00097-8 Occurrence Handle1:CAS:528:DC%2BD3cXkslKit7w%3D

    Article  CAS  Google Scholar 

  • L H Bi H Y Wang Y Shen E K Wang S J Dong (2003) Electrochem Com 5 913 Occurrence Handle1:CAS:528:DC%2BD3sXotVWlt7k%3D

    CAS  Google Scholar 

  • Z H Guo Y Shen F Zhao Mk Wang S J Dong (2004) Analyst 129 657 Occurrence Handle10.1039/b314645f Occurrence Handle1:CAS:528:DC%2BD2cXltVahsb8%3D

    Article  CAS  Google Scholar 

  • Y R Ma Q X Yang W He X L Wang (2001) J Natural Gas Chemistry 10 147 Occurrence Handle1:CAS:528:DC%2BD3MXotVWqsrY%3D

    CAS  Google Scholar 

  • White E H, Roswell D F (1985) Chemi- and bioluminescence. In: Burr J G (ed) Marcel Dekker, New York, p 215

Download references

Author information

Authors and Affiliations

  1. College of Chemistry and Materials Science, Shaanxi Normal University, 710062, Xi’an, P.R. China

    Guixin Li, Xingwang Zheng & Zhujun Zhang

Authors
  1. Guixin Li
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Xingwang Zheng
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Zhujun Zhang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Xingwang Zheng.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Li, G., Zheng, X. & Zhang, Z. Electrogenerated Chemiluminescence (ECL) Determination of Ephedrine with a Self-Assembly Multilayer Ni(II)-Polyluminol Modified Electrode. Microchim Acta 154, 153–161 (2006). https://doi.org/10.1007/s00604-005-0480-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00604-005-0480-y

Search

Navigation