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Preparation, Characterization, and Evaluation of Immuno Carbon Nanotubes

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Abstract.

Single-walled and multiple-walled carbon nanotubes were functionalized with bovine serum albumin protein to attain aqueous solubility and biocompatibility. These aqueous soluble carbon nanotube-protein conjugates were further conjugated with pathogen-specific antibody to form immuno carbon nanotubes. The experimental details on the conjugation and results from the characterization of the conjugates are presented. The potential of these immuno carbon nanotubes in the detection of pathogenic Escherichia coli O157:H7 was evaluated, and the evaluation results are discussed.

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Correspondence to Ya-Ping Sun.

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Lin, Y., Elkin, T., Taylor, S. et al. Preparation, Characterization, and Evaluation of Immuno Carbon Nanotubes. Microchim Acta 152, 249–254 (2006). https://doi.org/10.1007/s00604-005-0443-3

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