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Determination of Na, K, Rb and Cs Distribution in Human Brain Using Neutron Activation Analysis

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Abstract.

This study aims to investigate the distribution of Na, K, Rb and Cs in human brains (5 individuals, 12 brain parts, mean age: 75 years). Distribution of the trace metals between lipid fraction and brain tissue was investigated in solvent extraction experiments. Determinations were carried out by instrumental neutron activation analysis. The present results show a rather non-homogeneous distribution for Na and a relatively uniform distribution for K, Rb and Cs. The mean concentrations found are 7440 µg Na g−1 dry weight, 12800 µg K g−1, 14 µg Rb g−1 and 50 ng Cs g−1. A highly significant positive correlation was found between Rb and Cs. Solvent extraction experiments showed that 19% of Rb and 26% of Cs of the total content is located in lipid fraction.

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Authors and Affiliations

  1. Institute of Inorganic and Analytical Chemistry, L. Eötvös University, Pázmány Péter stny 1/A, H-1117, Budapest, Hungary

    Csilla Bélavári & Erzsébet Andrási

  2. Institute of Nuclear Techniques, Budapest University of Technology and Economics, Mûegyetem rkp. 9., H-1111, Budapest, Hungary

    Zsuzsa Molnár

  3. Department of Trace Elements in Health and Nutrition, Hahn-Meitner Institute für Kernforschung, Glienicker Straße 100, D-14109, Berlin, Germany

    Dieter Gawlik

Authors
  1. Csilla Bélavári
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  2. Erzsébet Andrási
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  3. Zsuzsa Molnár
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  4. Dieter Gawlik
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Correspondence to Erzsébet Andrási.

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Bélavári, C., Andrási, E., Molnár, Z. et al. Determination of Na, K, Rb and Cs Distribution in Human Brain Using Neutron Activation Analysis. Microchim. Acta 146, 187–191 (2004). https://doi.org/10.1007/s00604-004-0219-1

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  • DOI: https://doi.org/10.1007/s00604-004-0219-1

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