Abstract
We reported previously that a large vertical interval between the hepatic segment of the inferior vena cava (IVC) and right atrium (RA), referred to as the IVC-RA gap, was associated with more intraoperative bleeding during hemi-hepatectomy. We conducted a computational fluid dynamics (CFD) study to clarify the impact of fluid dynamics resulting from morphologic variations around the liver. The subjects were 10 patients/donors with a large IVC-RA gap and 10 patients/donors with a small IVC-RA gap. Three-dimensional reconstructions of the IVC and hepatic vessels were created from CT images for the CFD study. Median pressure in the middle hepatic vein was significantly higher in the large-gap group than in the small-gap group (P = 0.008). Differences in hepatic vein pressure caused by morphologic variation in the IVC might be one of the mechanisms of intraoperative bleeding from the hepatic veins.
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Abbreviations
- CFD:
-
Computational fluid dynamics
- CT:
-
Computed tomography
- IVC:
-
Inferior vena cava
- RA:
-
Right atrium
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Acknowledgements
This work was supported by JSPS KAKENHI grant no. 21K16450.
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This work was supported by JSPS KAKENHI grant no. 21K16450.
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Study conception and design: YI, YT, KS. Acquisition of data: YI, KT, KS. Analysis and interpretation of data: YI, KS. Drafting the manuscript: YI, KS. Critical revisions: YI, YT, KO, FN, KT, MH, TN, MU, YN, MS, AS, CI, MI. All authors have read and approved the final manuscript.
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Sakamoto, K., Iwamoto, Y., Ogawa, K. et al. Impact of the inferior vena cava morphology on fluid dynamics of the hepatic veins. Surg Today 54, 205–209 (2024). https://doi.org/10.1007/s00595-023-02733-6
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DOI: https://doi.org/10.1007/s00595-023-02733-6