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Laparoscopic multivisceral resection for locally advanced colon cancer: a single-center analysis of short- and long-term outcomes

Surgery Today volume 50, pages 1024–1031 (2020)Cite this article

Abstract

Purpose

We evaluated the technical and oncological safety of laparoscopic multivisceral resection (MVR) in selected patients with locally advanced colon cancer (LACC).

Methods

We compared the clinical backgrounds, and short- and long-term outcomes of patients who underwent laparoscopic vs. those who underwent open MVR for LACC en bloc at our hospital.

Results

Between January, 2004 and December, 2015, 140 patients underwent MVR of the primary tumor en bloc via laparoscopic surgery (laparoscopic group; LG, n = 69) or open surgery (open group; OG, n = 71). Laparoscopic surgery was selected mainly for tumors that invaded the bladder and abdominal wall. The LG patients had smaller tumors (60 vs. 80 mm, p < 0.001), less blood loss (30 vs. 181 g, p < 0.001), and shorter hospital stays (12 vs. 19 days, p < 0.001) than the OG patients. Open conversion was required for two patients. Postoperative complications and R0 resection were comparable between the groups. Local recurrence occurred in two LG patients and two OG patients. The 5-year cancer-specific survival, disease-free survival, and local disease-free survival of patients with pT4b disease were not significantly different between the LG and OG groups (90.3% vs. 75.2%, 71.2% vs. 67.6%, and 97.1% vs. 94.2%).

Conclusion

Although the LG included patients with lower risk, the short- and long-term outcomes were equivalent to those of the OG, which included patients with higher risk.

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Funding

We have no financial ties to disclose.

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Affiliations

  1. Department of Gastroenterological Surgery, Cancer Institute Hospital of the Japanese Foundation for Cancer Research, 3-10-6 Ariake, Koto-ku, Tokyo, 135-8550, Japan

    Toshiki Mukai, Toshiya Nagasaki, Takashi Akiyoshi, Yosuke Fukunaga, Tomohiro Yamaguchi, Tsuyoshi Konishi, Satoshi Nagayama & Masashi Ueno

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  1. Toshiki Mukai
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  2. Toshiya Nagasaki
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  3. Takashi Akiyoshi
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  4. Yosuke Fukunaga
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  5. Tomohiro Yamaguchi
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  6. Tsuyoshi Konishi
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  7. Satoshi Nagayama
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  8. Masashi Ueno
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by TM, TN, and TA. The first draft of the manuscript was written by TM and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Toshiki Mukai.

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Conflict of interest

We have no conflicts of interest to declare.

Ethical approval

This study was approved by the ethical committee of Cancer Institute Hospital (approval number: 2018-1109).

Informed consent

Informed consent was obtained from all participants in the study.

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Cite this article

Mukai, T., Nagasaki, T., Akiyoshi, T. et al. Laparoscopic multivisceral resection for locally advanced colon cancer: a single-center analysis of short- and long-term outcomes. Surg Today 50, 1024–1031 (2020). https://doi.org/10.1007/s00595-020-01986-9

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  • DOI: https://doi.org/10.1007/s00595-020-01986-9

Keywords

  • Laparoscopic surgery
  • Multivisceral resection
  • Colon cancer
  • Survival