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Surgery Today

, Volume 49, Issue 5, pp 394–400 | Cite as

Laparoscopic versus open distal pancreatectomy for benign and low-grade malignant lesions of the pancreas: a single-center comparative study

  • Ippei MatsumotoEmail author
  • Keiko Kamei
  • Shumpei Satoi
  • Takaaki Murase
  • Masataka Matsumoto
  • Kohei Kawaguchi
  • Yuta Yoshida
  • Toshimitsu Iwasaki
  • Atsushi Takebe
  • Takuya Nakai
  • Yoshifumi Takeyama
Original Article

Abstract

Purpose

The purpose of the study was to compare the outcomes of laparoscopic distal pancreatectomy (LDP) and open distal pancreatectomy (ODP) for benign and low-grade malignant lesions to determine the safety and efficacy of LDP.

Methods

This retrospective comparative study included 67 consecutive patients who underwent LDP (n = 32) and ODP (n = 35) for benign or low-grade malignant lesions of the pancreas from January 2012 to March 2017. Thirty-five patients who were eligible for LDP in the ODP group were carefully selected. The clinical outcomes were compared in an intention-to-treat analysis.

Results

LDP was associated with significantly less operative blood loss (182 ± 232 vs. 505 ± 376 ml, P < 0.001) but a longer operation time (327 ± 89 vs. 173 ± 48 min, P < 0.001), than ODP. There were no significant differences between the 2 groups in the overall morbidity rates defined by Clavien–Dindo classification ≥ grade II (13% vs. 11%), clinically relevant postoperative pancreatic fistula rates (6% vs. 9%), and lengths of postoperative hospital stay (11 vs. 11 days).

Conclusion

The study showed that LDP was safe and feasible. LDP should be considered as the first-line treatment for benign and low-grade malignant lesions in the left side of the pancreas.

Keywords

Laparoscopic distal pancreatectomy Laparoscopic pancreatectomy: benign and low-grade malignant lesions 

Notes

Acknowledgements

No grant support was provided for this study.

Compliance with ethical standards

Conflict of interest

The authors have no conflicts of interest to disclose.

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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Ippei Matsumoto
    • 1
    Email author
  • Keiko Kamei
    • 1
  • Shumpei Satoi
    • 1
  • Takaaki Murase
    • 1
  • Masataka Matsumoto
    • 1
  • Kohei Kawaguchi
    • 1
  • Yuta Yoshida
    • 1
  • Toshimitsu Iwasaki
    • 1
  • Atsushi Takebe
    • 1
  • Takuya Nakai
    • 1
  • Yoshifumi Takeyama
    • 1
  1. 1.Department of SurgeryKindai University Faculty of MedicineOsakasayamaJapan

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