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Single lung transplantation for lymphangioleiomyomatosis: a single-center experience in Japan

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A Correction to this article was published on 13 June 2018

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Abstract

Purpose

Lung transplantation is accepted as an effective modality for patients with end-stage pulmonary lymphangioleiomyomatosis (LAM). Generally, bilateral lung transplantation is preferred to single lung transplantation (SLT) for LAM because of native lung-related complications, such as pneumothorax and chylothorax. It remains controversial whether SLT is a suitable surgical option for LAM. The objective of this study was to evaluate the morbidity, mortality and outcome after SLT for LAM in a lung transplant center in Japan.

Methods

We reviewed the records of 29 patients who underwent SLT for LAM in our hospital between March, 2000 and November, 2017. The data collected included the pre-transplant demographics of recipients, surgical characteristics, complications, morbidity, mortality and survival after SLT for LAM.

Results

The most common complication after SLT for LAM was contralateral pneumothorax (n = 7; 24.1%). Six of these recipients were treated successfully with chest-tube placement and none required surgery for the pneumothorax. The second-most common complication was chylous pleural effusion (n = 6; 20.7%) and these recipients were all successfully treated by pleurodesis. The 5-year survival rate after SLT for LAM was 79.5%.

Conclusion

LAM-related complications after SLT for this disease can be managed. SLT is a treatment option and may improve access to lung transplantation for patients with end-stage LAM.

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Change history

  • 13 June 2018

    In the original publication, Fig. 3 has been incorrectly published. The correct version of Fig. 3 is given in this Correction.

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Acknowledgements

We thank Brent Bell for assistance with editing this manuscript.

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Authors and Affiliations

  1. Department of Thoracic Surgery, Institute of Development, Aging and Cancer, Tohoku University, 4-1 Seiryomachi, Aobaku, Sendai, 980-8575, Japan

    Hisashi Oishi, Tatsuaki Watanabe, Yasushi Matsuda, Masafumi Noda & Yoshinori Okada

  2. Department of Anesthesiology, Tohoku University Hospital, Sendai, Japan

    Yutaka Ejima

  3. Department of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan

    Yoshikatsu Saiki

  4. Division of Respiratory Medicine, Faculty of Medicine and Graduate School of Medicine, Juntendo University, Tokyo, Japan

    Kuniaki Seyama

  5. Department of Thoracic Surgery, Tohoku Medical and Pharmaceutical University, Sendai, Japan

    Takashi Kondo

Authors
  1. Hisashi Oishi
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  2. Tatsuaki Watanabe
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  3. Yasushi Matsuda
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  4. Masafumi Noda
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  5. Yutaka Ejima
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  6. Yoshikatsu Saiki
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  7. Kuniaki Seyama
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  8. Takashi Kondo
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  9. Yoshinori Okada
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Corresponding author

Correspondence to Hisashi Oishi.

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Conflict of interest

Hisashi Oishi and his co-authors have no conflicts of interest.

Additional information

The original version of this article was revised: In the original publication, Fig. 3 has been incorrectly published. Figure 3 is replaced.

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Oishi, H., Watanabe, T., Matsuda, Y. et al. Single lung transplantation for lymphangioleiomyomatosis: a single-center experience in Japan. Surg Today 48, 944–950 (2018). https://doi.org/10.1007/s00595-018-1678-z

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  • DOI: https://doi.org/10.1007/s00595-018-1678-z

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