Surgery Today

, Volume 48, Issue 5, pp 525–533 | Cite as

Risk and incidence of perioperative deep vein thrombosis in patients undergoing gastric cancer surgery

  • Tomohiro Osaki
  • Hiroaki Saito
  • Yoji Fukumoto
  • Yusuke Kono
  • Yuki Murakami
  • Yuji Shishido
  • Hirohiko Kuroda
  • Tomoyuki Matsunaga
  • Kengo Sato
  • Yasuaki Hirooka
  • Yoshiyuki Fujiwara
Original Article
  • 189 Downloads

Abstract

Background and purpose

Venous thromboembolism (VTE) is a potentially fatal perioperative complication. Understanding the risk factors for deep vein thrombosis (DVT) and initiating appropriate prophylaxis is pivotal for reducing the risk of VTE. The purpose of this study was to clarify the perioperative risk factors for DVT in patients undergoing surgery for gastric cancer.

Methods

We reviewed the findings of lower limb ultrasonography performed in 160 patients who underwent gastrectomy for gastric cancer.

Results

The preoperative and postoperative incidence of DVT was 4.4% (7/160) and 7.2% (11/153), respectively. All postoperative DVTs were of the distal type, whereas preoperative DVTs were of the proximal (n = 3) and distal type (n = 4). None of the patients suffered symptomatic VTE. Multivariate analysis indicated that depth of invasion and D-dimer concentration were independent risk factors for preoperative DVT and that gender and performance status were risk factors for postoperative DVT. Receiver operating characteristic analysis revealed that the optimal cut-off D-dimer concentration was 1.4 μg/mL.

Conclusions

The incidence of perioperative DVT was low for patients undergoing gastric cancer surgery. Therefore, the risk-stratified application of perioperative pharmacologic thromboprophylaxis is thought to be more appropriate than routine pharmacologic thromboprophylaxis for Japanese patients undergoing surgery for gastric cancer.

Keywords

Deep vein thrombosis Gastric cancer Thromboprophylaxis 

Notes

Compliance with ethical standards

Conflict of interest

The authors have no conflicting financial interests.

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Copyright information

© Springer Japan KK, part of Springer Nature 2017

Authors and Affiliations

  • Tomohiro Osaki
    • 1
  • Hiroaki Saito
    • 1
  • Yoji Fukumoto
    • 1
  • Yusuke Kono
    • 1
  • Yuki Murakami
    • 1
  • Yuji Shishido
    • 1
  • Hirohiko Kuroda
    • 1
  • Tomoyuki Matsunaga
    • 1
  • Kengo Sato
    • 2
  • Yasuaki Hirooka
    • 2
  • Yoshiyuki Fujiwara
    • 1
  1. 1.Division of Surgical Oncology, Department of Surgery, School of MedicineTottori University Faculty of MedicineYonagoJapan
  2. 2.Department of Pathobiological Science and Technology, School of Health SciencesTottori University Faculty of MedicineYonagoJapan

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