Skip to main content

Advertisement

Log in

Outcome and risk factors of recurrence after thoracoscopic bullectomy in young adults with primary spontaneous pneumothorax

  • Original Article
  • Published:
Surgery Today Aims and scope Submit manuscript

Abstract

Purpose

To investigate the risk factors of recurrence of pneumothorax following thoracoscopic bullectomy in young adults.

Methods

Between January, 2005 and September, 2015, 167 patients aged ≤40 years underwent initial thoracoscopic bullectomy for primary spontaneous pneumothorax (PSP) at our hospital. Recurrence-free probability was calculated from the date of surgery to recurrence or last follow-up, using the Kaplan–Meier method.

Results

Sixteen (9.6%) of the 167 patients suffered a recurrence (collective total, 16 recurrences). The recurrence-free intervals were 3–107 months (median 25.8 months), and the 5-year recurrence-free probability was 85.9%. Multivariate Cox analysis demonstrated that age ≤23 years (p = 0.029) and a history of ipsilateral pneumothorax before surgery (p = 0.029) were significantly associated with higher risk of recurrence. The 5-year recurrence-free probability was 72.3% for patients aged ≤23 years and a history of ipsilateral pneumothorax before surgery and 94.1% for those with neither of these factors (p = 0.001). Recurrence developed within 3 years after surgery in 14 of the 16 patients.

Conclusions

Patients ≤23 years of age with a history of ipsilateral pneumothorax before surgery are at significantly high risk of its recurrence, frequently within 3 years; thus, the risk of postoperative recurrence of a pneumothorax must be kept in mind.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Subscribe and save

Springer+ Basic
$34.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or eBook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Sahn SA, Heffner JE. Spontaneous pneumothorax. N Engl J Med. 2000;23(342):868–74.

    Article  Google Scholar 

  2. Zarogoulidis P, Kioumis I, Pitsiou G, Porpodis K, Lampaki S, Papaiwannou A, et al. Pneumothorax: from definition to diagnosis and treatment. J Thorac Dis. 2014;6(Suppl 4):S372–6.

    PubMed  PubMed Central  Google Scholar 

  3. Uramoto H, Shimokawa H, Tanaka F. What factors predict recurrence of a spontaneous pneumothorax? J Cardiothorac Surg. 2012;7:112.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Santillan-Doherty P, Argote-Greene LM, Guzman-Sanchez M. Thoracoscopic management of primary spontaneous pneumothorax. Am Surg. 2006;72:145–9.

    PubMed  Google Scholar 

  5. Barker A, Maratos EC, Edmonds L, Lim E. Recurrence rates of video-assisted thoracoscopic versus open surgery in the prevention of recurrent pneumothoraces: a systematic review of randomized and non-randomised trials. Lancet. 2007;370:329–35.

    Article  PubMed  Google Scholar 

  6. Muramatsu T, Nishii T, Takeshita S, Ishimoto S, Morooka H, Shiono M. Preventing recurrence of spontaneous pneumothorax after thoracoscopic surgery: a review of recent results. Surg Today. 2010;40:696–9.

    Article  PubMed  Google Scholar 

  7. Sakamoto K, Takei H, Nishii T, Maehara T, Omori T, Tajiri M, et al. Staple line coverage with absorbable mesh after thoracoscopic bullectomy for spontaneous pneumothorax. Surg Endosc. 2004;18:478–81.

    Article  CAS  PubMed  Google Scholar 

  8. Lee S, Kim HR, Cho S, Huh DM, Lee EB, Ryu KM, et al. Staple line coverage after bullectomy for primary spontaneous pneumothorax: a randomized trial. Ann Thorac Surg. 2014;98:2005–11.

    Article  PubMed  Google Scholar 

  9. Casadio C, Rena O, Giobbe R, Rigoni R, Maggi G, Oliaro A. Stapler blebectomy and pleural abrasion by video-assisted thoracoscopy for spontaneous pneumothorax. J Cardiovasc Surg. 2002;43:259–62.

    CAS  Google Scholar 

  10. Herrmann D, Klapdor B, Ewig S, Hecker E. Initial management of primary spontaneous pneumothorax with video-assisted thoracoscopic surgery: a 10-year experience. Eur J Cardiothorac Surg. 2015;. doi:10.1093/ejcts/ezv206.

    PubMed  Google Scholar 

  11. Cutler SJ, Ederer F. Maximum utilization of the life table method in analyzing survival. J Chronic Dis. 1958;8:699–712.

    Article  CAS  PubMed  Google Scholar 

  12. Kennecke HF, Olivotto IA, Speers C, Norris B, Chia SK, Bryce C, et al. Late risk of relapse and mortality among postmenopausal women with estrogen responsive early breast cancer after 5 years of tamoxifen. Ann Oncol. 2007;18:45–51.

    Article  CAS  PubMed  Google Scholar 

  13. Maeda R, Yoshida J, Ishii G, Aokage K, Hishida T, Nishimura M, et al. Long-term outcome and late recurrence in patients with completely resected stage IA non-small cell lung cancer. J Thorac Oncol. 2010;5:1246–50.

    Article  PubMed  Google Scholar 

  14. Schramel FM, Postmus PE, Vanderschueren RG. Current aspects of spontaneous pneumothorax. Eur Respir J. 1997;10:1372–9.

    Article  CAS  PubMed  Google Scholar 

  15. Choi SY, Kim YH, Jo KH, Kim CK, Park JK, Cho DG, et al. Video-assisted thoracoscopic surgery for primary spontaneous pneumothorax in children. Pediatr Surg Int. 2013;29:505–9.

    Article  PubMed  Google Scholar 

  16. West JB. Distribution of mechanical stress in the lung, a possible factor in localisation of pulmonary disease. Lancet. 1971;24(1):839–41.

    Article  Google Scholar 

  17. Moriyama S, Okutani D. Analysis of risk factors of recurrence of primary spontaneous pneumothorax (in Japanese with English abstract). Nihon Kikyo Nouhousei Haisikkann Gakkaizasshi (J Jpn Soc Pneumothorax Cystic Lung Dis). 2010; 10:96–100.

  18. Tschopp JM, Bintcliffe O, Astoul P, Canalis E, Driesen P, Janssen J, et al. ERS task force statement: diagnosis and treatment of primary spontaneous pneumothorax. Eur Respir J. 2015;46:321–35.

    Article  PubMed  Google Scholar 

  19. Huang TW, Lee SC, Cheng YL, Tzao C, Hsu HH, Chang H, et al. Contralateral recurrence of primary spontaneous pneumothorax. Chest. 2007;132:1146–50.

    Article  PubMed  Google Scholar 

  20. Imperatori A, Rotolo N, Spagnoletti M, Festi L, Berizzi F, Di Natale D, et al. Risk factors for postoperative recurrence of spontaneous pneumothorax treated by video-assisted thoracoscopic surgerydagger. Interact CardioVasc Thorac Surg. 2015;20:647–52.

    Article  PubMed  Google Scholar 

  21. Min X, Huang Y, Yang Y, Chen Y, Cui J, Wang C, et al. Mechanical pleurodesis does not reduce recurrence of spontaneous pneumothorax: a randomized trial. Ann Thorac Surg. 2014;98:1790–6.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Takashi Nakayama.

Ethics declarations

Conflict of interest

We have no competing interests to disclose.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Nakayama, T., Takahashi, Y., Uehara, H. et al. Outcome and risk factors of recurrence after thoracoscopic bullectomy in young adults with primary spontaneous pneumothorax. Surg Today 47, 859–864 (2017). https://doi.org/10.1007/s00595-016-1452-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00595-016-1452-z

Keywords

Navigation