Skip to main content
SpringerLink
Log in

An anisakis larva attached to early gastric cancer: report of a case

Surgery Today volume 45, pages 1321–1325 (2015)Cite this article

Abstract

Gastrointestinal anisakidosis is a nematode infection caused by the ingestion of larvae-infected raw or undercooked fish. The Japanese like to eat raw or undercooked fish, so gastric anisakiasis is a common disease in Japan. However, reports of anisakiasis with gastrointestinal cancer are rare. A 63-year-old Japanese male was diagnosed with a small early gastric cancerous lesion associated with gastric anisakiasis. From our experience and based on a review of the literature, the attachment of an anisakis larva to early gastric cancer is not considered accidental.

This is a preview of subscription content, access via your institution.

Access options

Buy single article

Instant access to the full article PDF.

USD 39.95

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Fig. 1
Fig. 2

References

  1. Matsui T, Iida M, Murakami M, Kimura Y, Fujishima M, Yao Y, et al. Intestinal anisakiasis: clinical and radiologic features. Radiology. 1985;157(2):299–302.

    Article  CAS  PubMed  Google Scholar 

  2. Bouree P, Paugam A, Petithory JC. Anisakidosis: report of 25 cases and review of the literature. Comp Immunol Microbiol Infect Dis. 1995;18(2):75–84.

    Article  CAS  PubMed  Google Scholar 

  3. van TP, Kuipers FC, Roskam RT. A nematode parasitic to herring, causing acute abdominal syndromes in man. Trop Geogr Med. 1960;12:97–113.

    Google Scholar 

  4. Hochberg NS, Hamer DH. Anisakidosis: perils of the deep. Clin Infect Dis. 2010;51(7):806–12.

    Article  PubMed  Google Scholar 

  5. Couture C, Measures L, Gagnon J, Desbiens C. Human intestinal anisakiosis due to consumption of raw salmon. Am J Surg Pathol. 2003;27(8):1167–72.

    Article  PubMed  Google Scholar 

  6. McKerrow JH, Sakanari J, Deardorff TL. Anisakiasis: revenge of the sushi parasite. N Engl J Med. 1988;319(18):1228–9.

    CAS  PubMed  Google Scholar 

  7. Smith JW. Thysanoessa inermis and T. longicaudata (Euphausiidae) as first intermediate hosts of Anisakis sp. (Nematoda: Ascaridata) in the northern North Sea, to the north of Scotland and at Faroe. Nature. 1971;234(5330):478.

    Article  CAS  PubMed  Google Scholar 

  8. Moore DA, Girdwood RW, Chiodini PL. Treatment of anisakiasis with albendazole. Lancet. 2002;360(9326):54.

    Article  PubMed  Google Scholar 

  9. Murata R, Suzuki J, Sadamasu K, Kai A. Morphological and molecular characterization of Anisakis larvae (Nematoda: Anisakidae) in Beryx splendens from Japanese waters. Parasitol Int. 2011;60(2):193–8.

    Article  CAS  PubMed  Google Scholar 

  10. Sugimachi K, Inokuchi K, Ooiwa T, Fujino T, Ishii Y. Acute gastric anisakiasis. Analysis of 178 cases. JAMA. 1985;253(7):1012–3.

    Article  CAS  PubMed  Google Scholar 

  11. Akbar A, Ghosh S. Anisakiasis—a neglected diagnosis in the West. Dig Liver Dis. 2005;37(1):7–9.

    Article  CAS  PubMed  Google Scholar 

  12. Kim H. Chronic gastric anisakiasis: radiologic and endoscopic features. AJR Am J Roentgenol. 1994;162(2):468–9.

    Article  CAS  PubMed  Google Scholar 

  13. Takei H, Powell SZ. Intestinal anisakidosis (anisakiosis). Ann Diagn Pathol. 2007;11(5):350–2.

    Article  PubMed  Google Scholar 

  14. Hayakawa H, Suzuki K, Maeda T, Oikawa K, Iishidate T. A case of IIa Type Early gastric cancer associated with eosinophilic granuloma (In Japanese). Stomach Intestine. 1970;5(2):223–7.

    Google Scholar 

  15. Nakajima H, Hamajima T. A case of early gastric cancer associated with eosinophlic granuloma (In Japanese). Akita J Rural Med. 1973;20:136–9.

    Google Scholar 

  16. Shinohara S, Ito Y, Hidaka Y, Sueo K, Katsura Y. A case of stomach cancer and coexistence of gastric anisakiasis (In Japanese). Jan J Clin Exp Med. 1973;48(5):1218–21.

    Google Scholar 

  17. Tsutsumi Y, Fujimoto Y. Early gastric cancer superimposed on infestation of an anisakis-like larva: a case report. Tokai J Exp Clin Med. 1983;8(3):265–73.

    CAS  PubMed  Google Scholar 

  18. Hirata N, Kim M, Maeda K, Nishiyama M, Akamatsu H, Kitagawa A, et al. A case of perforated duodenal ulcer, in which observed signet ring cell carcinoma and anisakis like larva (In Japanese). Jpn J Gastroenterol. 1988;21(5):1323–6.

    Article  Google Scholar 

  19. Hata Y, Matsukawa M, Nomura M, Yamashita K, Irie H. A case of early gastric cancer associated with eosinophilic granuloma. (In Japanese). Intern Med. 1988;62(4):755–8.

    Google Scholar 

  20. Kitamura A, Nakamura A, Nakata E, Nomura E, Minami M, Kawai T. Gastric anisakiasis and the properties of its background mucosa (In Japanese). Med Postgrad. 1991;29(2):62–6.

    Google Scholar 

  21. Yazaki S, Fukumoto S, Maejima J, Watanabe T, Takebayashi M, Matsui K. Anisakis larva found in the extirpated lymph node of a patient with gastric cancer. Yonago Acta Media. 1991;34(2):193–200.

    Google Scholar 

  22. Masuda K, Sakanoue K, Itakura S, Kagawa K, Itagaki T, Ishida H, et al. A case of parasitic eosinophilic granuloma of the stomach early gastric cancer(In Japanese). Matsue Red Cross Hosp Med J. 1991;3(1):65–8.

    Google Scholar 

  23. Hashiguthi J, Itho M, Sekine I, Yano A, Harada Y. A case of the anisakiasis on celiac lymph node with eosinophilia. (In Japanese). Nagasaki Igakkai Zasshi. 1992;67(4):258–60.

    Google Scholar 

  24. Shirasaki S, Miura M, Aida T, Fujino S, Sato F, Madoiwa S, et al. A case of early gastric cancer producing alpha-petoprotein associated with gastric anisakiasis. (In Japanese). Gastroenterol Endosc. 1992;34(3):576–9.

    Google Scholar 

  25. Nishikawa Y, Tokusa Y, Nishimori H, Ogawa K, Miyamoto K. A case of anisakiasis granuloma in omentum minus of gastrectomy. (In Japanese). Off J JpneAssoc Pathol. 1992;10(2):212.

    Google Scholar 

  26. Tochika N, Kumon M, Araki K. A case of ectopic anisakiasis complicating by an advanced gastric cancer. (In Japanese). J Jpn Surg Assoc. 1996;57(1):213–5.

    Google Scholar 

  27. Kuramochi J, Goseki N. A case of gastric anisakiasis embedded to gastric cancer. (In Japanese). J Jpn Surg Assoc. 2000;61(12):3236–8.

    Article  Google Scholar 

  28. Maggi P, Caputi-Iambrenghi O, Scardigno A, Scoppetta L, Saracino A, Valente M, et al. Gastrointestinal infection due to Anisakis simplex in southern Italy. Eur J Epidemiol. 2000;16(1):75–8.

    Article  CAS  PubMed  Google Scholar 

  29. Sakurai T, Niina I, Fujiwara M, Yamanari H, Shimayama T, Chijiiwa K. A case of ectopic anisakiasis associated with early gastric cancer. (In Japanese). J Jpn Surg Assoc. 2003;64(4):855–9.

    Article  Google Scholar 

  30. Saitho K, Hashida H, Iwashiro N, Ohrara M, Ishizaka M, Kondo S, et al. A case of IIc type early gastric cancer associated with eosinophilic granuloma produced by gastric anisakiasis. (In Japanese). J Jpn Surg Assoc. 2004;37(12):1829–33.

    Google Scholar 

  31. Shibahara K, Amaya S, Kurokawa M, Yagi S, Uozu K, Hasegawa H, et al. A surgical case of advanced gastric cancer with scirrhous like endoscopic finding probably due to anisakiasis of the stomach. (In Japanese). J Jpn Surg Assoc. 2004;65(5):1241–4.

    Article  Google Scholar 

  32. Meguro E, Inaba T, Irinoda T, Hayakawa Y, Okada S, Kaizuka H. A patient with early gastric cancer incidentally detected during treatment for acute anisakiasis. (In Japanese). Geka. 2005;62(2):226–9.

    Google Scholar 

  33. Ohishi T, Hasuoka H, Kagei N. A case of anisakis laeva in lymph node of gastrectomy for gastric cancer. (In Japanese). Clin Parasitol. 2005;15(1):57–8.

    Google Scholar 

  34. Mineta S, Shimanuki K, Sugiura A, Tsuchiya Y, Kaneko M, Sugiyama Y, et al. Chronic anisakiasis of the ascending colon associated with carcinoma. J Nippon Med Sch. 2006;73(3):169–74.

    Article  PubMed  Google Scholar 

  35. Katho T, Matsui T. Clinical study of 101 cases of early gastric cancer, which was discovered in 20 years in our hospital. (In Japanese). J Med Assoc South Hokkaido. 2005;40:13.

    Google Scholar 

  36. Sunagawa K, Fuchinoue F, Homma T, Kinukawa N, Oinuma T, Hayashi K, et al. Clinical and pathological study of intestinal anisakiasis. (In Japanese). Jpn J Diagn Pathol. 2007;24(2):175–7.

    Google Scholar 

  37. Satho M, Hiraga M, Shiiba K. A case of asymptomatic colonic anisakiasis during colonoscopy for preoperation of gastric cancer (In Japanese). J Jpn Soc Coloproctol. 2007;60(7):421–5.

    Article  Google Scholar 

  38. Yoo HJ, Kim SH, Lee JM, Kim MA, Han JK, Choi BI. The association of anisakiasis in the ascending colon with sigmoid colon cancer: CT colonography findings. Korean J Radiol. 2008;9(Suppl):S56–60.

    Article  PubMed Central  PubMed  Google Scholar 

  39. Ohira T, Hirasawa D, Noda Y, Suzuki T, Sugawara T, Harada Y, et al. A case of early gastric cancer associated with granuloma due to anisakis directly under the tumor. (In Japanese). Endoscopia Digestiva. 2009;21(11):1757–62.

    Google Scholar 

  40. Hiramoto K, Kuriki M, Nakano E, Nanno N, Matsumura Y, Miura A, et al. A case of ascending colon cancer in which an anisakis parasite was revealed protruding from the tumor during colonoscopy. (In Japanese). Gastroenterol Endosc. 2012;54(5):1656–61.

    Google Scholar 

  41. Hernandez-Prera JC, Polydorides AD. Anisakidosis of the sigmoid colon disguising as metastatic carcinoma: a case report and review of the literature. Pathol Res Pract. 2012;208(7):433–5.

    Article  PubMed  Google Scholar 

  42. Iino H, Tomioka T, Akaiwa J. About parasitic granuloma, anisakiasis and anisakis-like larva of stomach. (In Japanese). Stomach Intestine. 1969;4:601–8.

    Google Scholar 

Download references

Conflict of interest

None declared.

Author information

Authors and Affiliations

  1. Department of General Surgery, Imari Arita Kyoritsu Hospital, Saga, 849-4193, Japan

    Hideto Sonoda, Kazuharu Yamamoto, Kazuyuki Ozeki & Humio Inoye

  2. Department of Pathology and Microbiology, Saga University, Saga, 849-8501, Japan

    Shuji Toda

  3. Departments of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812-8582, Japan

    Yoshihiko Maehara

Authors
  1. Hideto Sonoda
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Kazuharu Yamamoto
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Kazuyuki Ozeki
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Humio Inoye
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Shuji Toda
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Yoshihiko Maehara
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Hideto Sonoda.

Rights and permissions

Reprints and Permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sonoda, H., Yamamoto, K., Ozeki, K. et al. An anisakis larva attached to early gastric cancer: report of a case. Surg Today 45, 1321–1325 (2015). https://doi.org/10.1007/s00595-014-1012-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00595-014-1012-3

Keywords

search

Navigation