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Acute malignant intestinal obstruction accompanied by synchronous multifocal intestinal cancer in Peutz–Jeghers syndrome: report of a case

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Abstract

Acute mechanical intestinal obstruction is one of the most common modes of presentation in patients with Peutz–Jeghers syndrome (PJS). This report presents a case of PJS with malignant acute jejunal obstruction accompanied by synchronous foci of duodenal, jejunal, and ileal cancer originated from hamartomatous polyps. The follow-up endoscopic findings of the patient also revealed severe polyposis of the entire gastrointestinal tract, including the stomach and colon, in addition to the small intestine. Very few cases of multifocal synchronous small intestinal cancer in PJS patients have been reported in the previous literature.

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References

  1. Giardiello FM, Trimbath JD. Peutz–Jeghers syndrome and management recommendations. Clin Gastroenterol Hepatol. 2006;4:408–15.

    Article  PubMed  Google Scholar 

  2. Ben Brahim E, Jouini R, Khayat O, Labbène N, Bel Haj Salah M, Koubâa W, et al. Adenomatous transformation in hamartomatous polyps cases of two patients with Peutz–Jeghers syndrome. Int J Colorectal Dis 2009;24:1361–63.

    Google Scholar 

  3. Derici H, Peker Y, Tatar F, Cin N, Deniz V. Multiple malign gastrointestinal polyps and rectal carcinoma in a young patient with Peutz–Jeghers syndrome. Int J Colorectal Dis. 2007;22:85–6.

    Article  PubMed  Google Scholar 

  4. Aiyappan SK, Kang M, Yadav TD, Radotra BD, Khandelwal N. Duodenojejunal intussusception in Peutz–Jeghers syndrome: report of a case. Surg Today. 2010;40:1179–82.

    Article  PubMed  Google Scholar 

  5. Akimaru K, Katoh S, Ishiguro S, Miyake K, Shimanuki K, Tajiri T. Resection of over 290 polyps during emergency surgery for four intussusceptions with Peutz–Jeghers syndrome: report of a case. Surg Today. 2006;36:997–1002.

    Article  PubMed  Google Scholar 

  6. Buck JL, Harned RK, Lichtenstein JE, Sobin LH. Peutz–Jeghers syndrome. Radiographics. 1992;12:365–8.

    PubMed  CAS  Google Scholar 

  7. Zbuk KM, Eng C. Hamartomatous polyposis syndromes. Natl Clin Pract Gastroenterol Hepatol. 2007;4:492–502.

    Article  CAS  Google Scholar 

  8. Jamaludin AZ, Telisinghe PU, Yapp SK, Chong VH. Solitary duodenal hamartomatous polyp with malignant transformation: report of a case. Surg Today. 2009;39:527–32.

    Article  PubMed  Google Scholar 

  9. McGarrity TJ, Kulin HE, Zaino RJ. Peutz–Jeghers syndrome. Am J Gastroenterol. 2000;95:596–604.

    Article  PubMed  CAS  Google Scholar 

  10. Giardiello FM, Welsh SB, Hamilton SR, Offerhaus GJ, Gittelsohn AM, Booker SV, et al. Increased risk of cancer in the Peutz-Jeghers syndrome. N Engl J Med. 1987;316(24):1511–4.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of General Surgery, Istanbul Medeniyet University Goztepe Education and Research Hospital, Dr. Erkin Street, Kadikoy, Istanbul, Turkey

    Tunc Eren, Baris Bayraktar, Yahya Celik & Salih Boluk

  2. Department of Gastroenterology, Istanbul Medeniyet University Goztepe Education and Research Hospital, Istanbul, Turkey

    Gupse Adali

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  1. Tunc Eren
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  2. Baris Bayraktar
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  3. Yahya Celik
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  4. Salih Boluk
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  5. Gupse Adali
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Correspondence to Tunc Eren.

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Eren, T., Bayraktar, B., Celik, Y. et al. Acute malignant intestinal obstruction accompanied by synchronous multifocal intestinal cancer in Peutz–Jeghers syndrome: report of a case. Surg Today 42, 1125–1129 (2012). https://doi.org/10.1007/s00595-012-0165-1

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  • DOI: https://doi.org/10.1007/s00595-012-0165-1

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