Abstract
We herein report a case of a gastric schwannoma with elevated preoperative serum carbohydrate antigen 19-9 (CA19-9) (155.2 U/ml, normal range 0–36.9 U/ml). A 59-year-old Japanese man was admitted to our hospital for treatment of a submucosal tumor of the stomach detected by barium meal, upper gastrointestinal endoscopy, and computed tomography. Endoscopic examination revealed a 3-cm diameter submucosal tumor in the antrum of the stomach, but biopsy of the lesion was unable to confirm the diagnosis. Positron emission tomography to evaluate the malignant potential showed a high uptake of 18F-fluorodeoxyglucose in the tumor. Laparoscopy-assisted distal gastrectomy was therefore performed. The histopathological findings of the surgical specimen revealed a benign gastric schwannoma, positive for S-100 protein. The postoperative serum CA19-9 levels gradually decreased and normalized. To the best of our knowledge, this is the first report of a gastric schwannoma with elevated serum CA19-9.
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Minoru Fukuchi and co-authors (Hiroshi Naitoh, Hisanori Shoji, Junko Yamagishi, Masaki Suzuki, Toru Yanoma, Shinsuke Kiriyama, and Hiroyuki Kuwano) have no conflict of interest.
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Fukuchi, M., Naitoh, H., Shoji, H. et al. Schwannoma of the stomach with elevated preoperative serum carbohydrate antigen 19-9: report of a case. Surg Today 42, 788–792 (2012). https://doi.org/10.1007/s00595-011-0066-8
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DOI: https://doi.org/10.1007/s00595-011-0066-8