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Solid pseudopapillary tumor of the pancreas: The surgical procedures

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Abstract

Purpose

To evaluate the clinicopathological characteristics of solid pseudopapillary tumor and assess the curative effects of different procedures.

Methods

A retrospective review was performed in 34 patients with this tumor surgically treated between January 2000 and June 2008. These patients were divided into minimized and standard resection groups. The clinical data of the two groups were analyzed.

Results

Thirty-one females and three males were included in this study. There were no significant differences in age, blood glucose, hemoglobin, and albumin between the two groups. The surgical time for patients with a standard resection was longer (225 vs 124 min, P = 0.004), the transfusion rate was higher (52.6% vs 13.3%, P = 0.030), and the hospital stay was prolonged (21 vs 16 days, P = 0.034) in comparison to those who underwent a minimized resection. The complications rate in the standard resection group was higher than that in the minimized resection group, although no significant difference was found (42.1% vs 26.7%, P = 0.476). The long-term follow-up showed that all of the patients survived without recurrence except for one patient who died of other diseases 29 months after surgery.

Conclusion

A solid pseudopapillary tumor is a latent malignant tumor with excellent prognosis after its complete removal. When feasible, a minimized resection, such as enucleation and a segmental pancreatectomy, is a suitable approach, with excellent early and long-term results.

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References

  1. Santini D, Poli F, Lega S. Solid-papillary tumours of the pancreas: histopathology. JOP J Pancreas (Online) 2006;7:131–136.

    Google Scholar 

  2. Kloppel G, Solcia E, Longnecker DS, Capella C, Sobin LH. Histological typing of tumours of the exocrine pancreas. In: World Health Organization: international histological classification of tumours. Berlin: Springer; 1996. p. 11–20.

    Google Scholar 

  3. Bassi C, Dervenis C, Butturini G, Fingerhut A, Yeo C, Izbicki J, et al. Postoperative pancreatic fistula: an international study group (ISGPF) definition. Surgery 2005;138:8–13.

    Article  PubMed  Google Scholar 

  4. Frantz VK. Tumours of the pancreas. In: Atlas of tumor pathology. Washington, DC: Armed Forces Institute of Pathology; 1959. p. 32–33.

    Google Scholar 

  5. Sun CD, Lee WJ, Choi JS, Oh JT, Choi SH. Solid-pseudopapillary tumours of the pancreas: 14 years experience. ANZ J Surg 2005;75:684–689.

    Article  PubMed  Google Scholar 

  6. Rebhandl W, Felberbauer FX, Puig S, Paya K, Hochschorner S, Barlan M, et al. Solid-pseudopapillary tumor of the pancreas (Frantz tumor) in children: report of four cases and review of the literature. J Surg Oncol 2001;76:289–296.

    Article  CAS  PubMed  Google Scholar 

  7. Madan AK, Weldon CB, Long WP, Johnson D, Raafat A. Solid and papillary epithelial neoplasm of the pancreas. J Surg Oncol 2004;85:193–198.

    Article  PubMed  Google Scholar 

  8. Salvia R, Bassi C, Festa L, Falconi M, Crippa S, Butturini G, et al. Clinical and biological behavior of pancreatic solid pseudopapillary tumors: report on 31 consecutive patients. J Surg Oncol 2007;95:304–310.

    Article  PubMed  Google Scholar 

  9. Zhang H, Liang TB, Wang WL, Shen Y, Ren GP, Zheng SS. Diagnosis and treatment of solid-pseudopapillary tumor of the pancreas. Hepatobiliary Pancreat Dis Int 2006;5:454–458.

    PubMed  Google Scholar 

  10. Aydiner F, Erinanç H, Sava B, Erden E, Karayalçin K. Solid pseudopapillary tumor of the pancreas: emphasis on differential diagnosis from aggressive tumors of the pancreas. Turk J Gastroenterol 2006;17:219–222.

    PubMed  Google Scholar 

  11. Ng KH, Tan PH, Thng CH, Ooi LL. Solid pseudopapillary tumor of the pancreas. ANZ J Surg 2003;73:410–415.

    Article  PubMed  Google Scholar 

  12. Seo HE, Lee MK, Lee YD, Jeon SW, Cho CM, Tak WY, et al. Solid-pseudopapillary tumor of the pancreas. J Clin Gastroenterol 2006;40:919–922.

    Article  PubMed  Google Scholar 

  13. Sperti C, Berselli M, Pasquali C, Pastorelli D, Pedrazzoli S. Aggressive behaviour of solid-pseudopapillary tumor of the pancreas in adults: a case report and review of the literature. World J Gastroenterol 2008;14:960–965.

    Article  PubMed  Google Scholar 

  14. Chen X, Zhou GW, Zhou HJ, Peng CH, Li HW. Diagnosis and treatment of solid-pseudopapillary tumors of the pancreas. Hepatobiliary Pancreat Dis Int 2005;4:456–459.

    PubMed  Google Scholar 

  15. Kasem A, Ali Z, Ellul J. Papillary cystic and solid tumor of the pancreas: report of a case and literature review. World J Surg Oncol 2005;3:62.

    Article  PubMed  Google Scholar 

  16. Karagülle E, Yildirim E, Türk E, Kiyici H, Karakayali H. Solid pseudopapillary tumor of the pancreas: a case report. Turk J Gastroenterol 2006;17:316–319.

    PubMed  Google Scholar 

  17. Adamthwaite JA, Verbeke CS, Stringer MD, Guillou PJ, Menon KV. Solid pseudopapillary tumour of the pancreas: diverse presentation, outcome and histology. JOP J Pancreas (Online) 2006;7:635–642.

    Google Scholar 

  18. Tang LH, Aydin H, Brennan MF, Klimstra DS. Clinically aggressive solid pseudopapillary tumors of the pancreas: a report of two cases with components of undifferentiated carcinoma and a comparative clinicopathologic analysis of 34 conventional cases. Am J Surg Pathol 2005;29:512–519.

    Article  PubMed  Google Scholar 

  19. De Castro SM, Singhal D, Aronson DC, Busch OR, van Gulik TM, Obertop H, et al. Management of solid-pseudopapillary neoplasms of the pancreas: a comparison with standard pancreatic neoplasms. World J Surg 2007;31:1130–1135.

    Article  PubMed  Google Scholar 

  20. Casadei R, Santini D, Calculli L, Pezzilli R, Zanini N, Minni F. Pancreatic solid-cystic papillary tumor: clinical features, imaging findings and operative management. JOP J Pancreas (Online) 2006;7:137–144.

    Google Scholar 

  21. Shaikh S, Arya S, Ramadwar M, Barreto SG, Shukla PJ, Shrikhande SV. Three cases of unusual solid pseudopapillary tumors. Can radiology and histology aid decision-making? JOP J Pancreas (Online) 2008;9:150–159.

    Google Scholar 

  22. Rund CR, Moser AJ, Lee KK, Zeh HJ, Teot LA, Dacic S, et al. Array comparative genomic hybridization analysis of solid pseudopapillary neoplasms of the pancreas. Mod Pathol 2008;21:559–564.

    Article  CAS  PubMed  Google Scholar 

  23. Kang CM, Kim KS, Choi JS, Kim H, Lee WJ, Kim BR. Solid pseudopapillary tumor of the pancreas suggesting malignant potential. Pancreas 2006;32:276–280.

    Article  PubMed  Google Scholar 

  24. Balaratnasingam C, Samnakay N, Hamdorf JM. Solid-pseudopapillary neoplasm of pancreas. ANZ J Surg 2004;74:914–915.

    Article  PubMed  Google Scholar 

  25. Peng CH, Chen DF, Zhou GW, Yang WP, Tao ZY, Lei RQ, et al. The solid-pseudopapillary tumor of pancreas: the clinical characteristics and surgical treatment. J Surg Res 2006;131:276–282.

    Article  PubMed  Google Scholar 

  26. Mao C, Guvendi M, Domenico DR, Kim K, Thomford NR, Howard JM, et al. Papillary cystic and solid tumors of the pancreas: a pancreatic embryonic tumor? Studies of three cases and cumulative review of the world’s literature. Surgery 1995;118(5):821–828.

    Article  CAS  PubMed  Google Scholar 

  27. Nagri S, Abdu A, Anand S, Krishnaiah M, Arya V. Liver metastasis four years after Whipple’s resection for solid-pseudopapillary tumour of the pancreas. JOP J Pancreas (Online) 2007;8:223–227.

    Google Scholar 

  28. Martin RC, Klimstra DS, Brennan MF, Conlon KC. Solidpseudopapillary tumour of the pancreas: a surgical enigma? Ann Surg Oncol 2002;9:35–40.

    Article  PubMed  Google Scholar 

  29. Vollmer C, Dixon E, Grant D. Management of a solid pseudopapillary tumour of the pancreas with liver metastases. HPB (Oxford) 2003;5:264–267.

    Google Scholar 

  30. Goh BK, Tan YM, Cheow PC, Chung AY, Chow PK, Wong WK, et al. Solid pseudopapillary neoplasms of the pancreas: an updated experience. J Surg Oncol 2007;95:640–644.

    Article  PubMed  Google Scholar 

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Li, Z., Zhang, Z., Liu, X. et al. Solid pseudopapillary tumor of the pancreas: The surgical procedures. Surg Today 41, 91–96 (2011). https://doi.org/10.1007/s00595-009-4225-0

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  • DOI: https://doi.org/10.1007/s00595-009-4225-0

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