Abstract
A 56-year-old man was referred with lower rectal cancer showing anal canal invasion and liver metastasis. He underwent an abdominoperineal resection and a partial hepatectomy. Adjuvant therapy with tegafur-uracil and leucovorin was administered postoperatively. Lung metastasis was detected 2 years later and was resected. Right mandibular metastasis was diagnosed 2 months after the resection of the lung metastasis. A partial mandibular resection was performed after chemoradiotherapy, followed by reconstruction with a titanium frame and oral cavity reconstruction with a greater pectoral musculocutaneous flap. The pathological diagnosis was metastatic rectal cancer, and the therapeutic effect chemoradiotherapy was Grade 2. He is presently alive without any evidence of cancer, and has maintained a good quality of life 3 years after the mandibular resection and more than 5 years after his first operation. Mandibular metastasis from rectal cancer is very rare and the prognosis is poor according to the literature, so this case is considered to be very unusual.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Kayashima H, Taketomi A, Yamashita Y, Kuroda Y, Kitagawa D, Harimoto N, et al. Liver metastasis with intraductal invasion originating from rectal cancer: report of a case. Surg Today 2008;38:765–768.
Tsuru S, Kurokawa H, Sugimoto T, Kajiyama M, Masuda H, Kusaba I, et al. Liver carcinoma and rectal carcinoma metastatic to the oral region: report of two cases (in Japanese with English abstract). Jpn J Cancer Clin 1995;41:1243–1248.
Nishimura Y, Yakata H, Kawasaki T, Nakajima T. Metastatic tumours of the mouth and jaws. A review of the Japanese literature. J Maxillofac Surg 1982;10:253–258.
Abiko Y, Shibata T, Nagayasu H, Kitajyo H, Ohuchi T, Nakade O, et al. An autopsy case of the rectal carcinoma with metastasis to the oral region (in Japanese with English abstract). Higashi Nippon Dent J 1997;16:295–300.
Yoshimoto K, Toyama Y, Watanabe K, Kashiwagi H, Hirai K, Yanaga K. A case of thyroid metastasis from rectal cancer over 5 years after operation (in Japanese with English abstract). Nihon Rinsho Geka Gakkai Zasshi 2007;68:2831–2835.
Hirshberg A, Shnaiderman-Shapiro A, Kaplan I, Berger R. Metastatic tumours to the oral cavity—pathogenesis and analysis of 673 cases. Oral Oncol 2008;44:743–752.
Lim SY, Kim SA, Ahn SG, Kim HK, Kim SG, Hwang HK, et al. Metastatic tumours to the jaws and oral soft tissues: a retrospective analysis of 41 Korean patients. Int J Oral Maxillofac Surg 2006;35:412–415.
van der Waal RI, Buter J, van der Waal I. Oral metastases: report of 24 cases. Br J Oral Maxillofac Surg 2003;41:3–6.
Bodner L, Sion-Vardy N, Geffen DB, Nash M. Metastatic tumors to the jaws: a report of eight new cases. Med Oral Patol Oral Cir Bucal 2006;11:E132–E135.
Mason AC, Azari KK, Farkas LM, Duvvuri U, Myers EN. Metastatic adenocarcinoma of the colon presenting as a mass in the mandible. Head Neck 2005;27:729–732.
Lowy AM, Rich TA, Skibber JM, Dubrow RA, Curley SA. Preoperative infusional chemoradiation, selective intraoperative radiation, and resection for locally advanced pelvic recurrence of colorectal adenocarcinoma. Ann Surg 1996;223:177–185.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Soda, H., Doi, K., Kinoshita, T. et al. Mandibular bone metastasis of rectal cancer: Report of a case. Surg Today 40, 1188–1191 (2010). https://doi.org/10.1007/s00595-009-4197-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00595-009-4197-0