Abstract
A 58-year-old woman was admitted to our hospital to optimize the management of her diabetes mellitus. A computed tomography (CT) scan showed a 30-mmdiameter, multilocular cyst in the head of the pancreas. The tumor markers, including DUPAN 2, SPAN-1, and carbohydrate antigen 19-9, were within the normal ranges. A contrast-enhanced CT scan showed a nonenhanced, multilocular cyst. Abdominal magnetic resonance imaging showed a multilocular cyst. Endoscopic retrograde cholangiopancreatography showed that the main pancreatic duct was normal. Based on these findings, we suspected a branch duct type intraductal papillary mucinous neoplasm. A distal pancreatectomy with a splenectomy was performed, since more of the mass was located on the dorsolateral side, inconsistent with the preoperative imaging results. On the resected specimen, a 4-cm-diameter, multilocular cyst containing serous fluid was found. Pathologically, the cyst wall was lined with squamous epithelium surrounded by abundant lymphoid tissue with follicles, consistent with a lymphoepithelial cyst of the pancreas, which is an unusual benign cyst.
Similar content being viewed by others
References
Luchtrath H, Schriefers KH. Pankreaszyste unter dem Bild einer Sogenannten Brachiogenen Zyste. Der Pathologe 1985;6:217–219.
Truong LD, Rangdaeng S, Jordan P. Lymphoepithelial cyst of the pancreas. Am J Surg Pathol 1987;11:899–903.
Truong LD, Stewart MG, Hao H, Yutani C, Jordan PH. A comprehensive characterization of lymphoepithelial cyst associated with the pancreas. Am J Surg 1995;170:27–32.
Adsay NV, Hasteh F, Cheng JD, Klimstra DS. Squamous-lined cysts of the pancreas: lymphoepithelial cysts, dermoid cysts (teratomas), and accessory-splenic epidermoid cysts. Semin Diagn Pathol 2000;17:56–65.
Frezza EE, Wachtel MS. Lymphoepithelial cyst of the pancreas tail. Case report and review of the literature. J Pancreas 2008;9:46–49.
Pablo C, Mario LI, Mario M, Patricio M, Favier H, Francisco C, et al. Lymphoepithelial cysts of the pancreas: case report and review of the literature. J Gastrointest Surg 2004;8:342–345.
Kim YH, Auh YH, Kim KW, Lee MG, Kim KS, Park SY. Lymphoepithelial cysts of the pancreas: CT and sonographic findings. Abdom Imaging 1998;23:185–187.
Koga H, Yakayasu K, Mukai K, Muramatsu Y, Mizuguchi Y, Furukawa H, et al. CT of lymphoepithelial cyst of the pancreas. J Comput Assist Tomogr 1995;19:221–224.
Ahlawat SK. Lymphoepithelial cyst of pancreas. role of endoscopic ultrasound guided fine needle aspiration. J Pancreas 2008;9:230–234.
Policarpio-Nicolas ML, Shami VN, Kahaleh M, Adams RB, Malley S, Stanley MW, et al. Fine-needle aspiration cytology of pancreatic lymphoepithelial cysts. Cancer Cytopathol 2006;108:501–506.
Idetsu A, Ojima H, Saito K, Hirayama I, Hosouchi Y, Nishida Y, et al. Lymphoepithelial cyst of the pancreas: report of a case. Surg Today 2008;38:68–71.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Fukunaga, N., Ishikawa, M., Minato, T. et al. Lymphoepithelial cyst of the pancreas that was difficult to distinguish from branch duct-type intraductal papillary mucinous neoplasm: Report of a case. Surg Today 39, 901–904 (2009). https://doi.org/10.1007/s00595-009-3949-1
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00595-009-3949-1