Abstract
We report a case of Horner’s syndrome (HS) occurring as a complication after total thyroidectomy. Horner’s syndrome is characterized by myosis, eyelid ptosis, enophthalmos, and lack of sweating, with vascular dilatation of the lateral part of the face, caused by damage of the cervical sympathetic chain. We found only 28 other reports of HS developing after thyroidectomy, and only seven of these patients recovered completely. Of the 495 thyroidectomies performed at our hospital between 1997 and 2007, only one (0.2%) was complicated by the development of HS. The patient was a 35-year-old woman who underwent total thyroidectomy for Basedow-Graves’ disease. Horner’s syndrome manifested on postoperative day 2, but without anhydrosis or vascular dilatation of the face, and the symptoms resolved spontaneously 3 days later. The possible causes of HS after thyroidectomy include postoperative hematoma, ischemia-induced neural damage, and stretching of the cervical sympathetic chain by the retractor. The prompt and complete recovery of this patient suggests that the cervical sympathetic chain was damaged by retractor stretching.
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Leuchter I, Becker M, Mickel R, Dulguerov P. Horner’s syndrome and thyroid neoplasm. J Otorhinolaryngol 2002;64:49–52.
Chengiz K, Aykin A, Demirci A, Diren B. Intrathoracic goiter with hyperthyroidism, tracheal compression, superior vena cava syndrome, and Horner’s syndrome. Chest 1990;97:1005–1006.
Rios Zambudio A, Rodriguez Gonzalez JM, Balsalobre Salmeron MD, Parrilla Paricio P. Claude-Bernard-Horner syndrome secondary to an intrathoracic toxic multinodular goiter. Rev Clin Esp 2002;202:672–674.
Kezachian B, Lebrun C, Thomas P, Santini J, Freychet P, Sadoul JL. Horner’s syndrome secondary to begin multinodular goitre with hyperthyroidism. Eur J Med 1993;2:440–441.
Levin R, Newman SA, Login IS. Bilateral Horner’s syndrome secondary to multinodular goiter. Ann Intern Med 1986;105:550–551.
Kaelin W. Dtsch Z Chir 1915;194:395.
De Quervain F. Weiteres zur technik der kropfoperation. Dtsch Z Chir 1915;134:475–480.
Fritsche E. Radikale kropfoperation und kropfprophylaxe. Schweiz Med Wschr 1921;2:1016.
Dubs J. Klinische erfahrungen bei 840 kropfoperationen, mit besonderer berucksichtigung der kropf-recidive und recidivoperationen. Schweiz Med Wschr 1922;3:921.
Lange MJ. Morbidity and mortality in thyroidectomy. Proc R Soc Med 1961;54:871–873.
Beahrs OH, Vandertold DJ. Complications of secondary thyroidectomy. Surg Gynecol Obstet 1963;117:535–539.
Smith I, Murley RS. Damage to the cervical sympathetic system during operations on the thyroid gland. Br J Surg 1965;52:673–675.
Solomon P, Irish J, Gullane P. Horner’s syndrome following a thyroidectomy. J Otolaryngol 1993;22:454–456.
Noczynski L, Bielicki F, Dolinski J. Damage of the cervical part of the sympathetic trunk following surgery on the thyroid gland. Pol Przegl Chir 1976;48:883–887.
Rosato L, Avenia N, Bernante P, De Palma M, Gulino G, Nasi PG, et al. Complications of thyroid surgery: analysis of a multicentric study on 14934 patients operated on in Italy over five years. World J Surg 2004;28:271–276.
Raffaelli M, Iacobone M, Henry JF. The false non recurrent inferior laryngeal nerve. Surgery 2000;128:1082–1087.
El Hajjaji M, Deflorenne C, Dachy B. Horner’s syndrome associated with Guillain-Barré syndrome. Rev Neurol 2003;159:799–800.
Riedel A, Braune S, Kerum G, Schulte-Monting J, Lucking CH. Quantitative sudomotor axon reflex test (QSART): a new approach for testing distal sites. Muscle Nerve 1999;22:1257–1264.
Morris JGL, Lee J, Lim CL. Facial sweating in Horner’s syndrome. Brain 1984, 107:751–758.
Weisman AD, Adams RD. The neurological complications of dissecting aortic aneurysm. Brain 1944;67:69–71.
Harding JL, Sywak MS, Sidhu S, Delbridge LW. Horner’s syndrome in association with thyroid and parathyroid disease. Aust NZ J Surg 2004;74:442–445.
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Cozzaglio, L., Coladonato, M., Doci, R. et al. Horner’s syndrome as a complication of thyroidectomy: Report of a case. Surg Today 38, 1114–1116 (2008). https://doi.org/10.1007/s00595-007-3741-z
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DOI: https://doi.org/10.1007/s00595-007-3741-z